Shikalkin

ChemicalBook > CAS DataBase List > Shikalkin

Product Name: Shikalkin
CAS No.: 54952-43-1
Chemical Name: Shikalkin
Synonyms: shiconin;Arnebin-4;SHIKALKIN;Nsc 291845;(+-)-Shikonin;(Rac)-Shikonin;Shikonin >=98% (HPLC);Shikonin (mixture of optical isomers, about 1:1);5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-enyl)naphthalene-1,4-dione;5,8-dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)naphthalene-1,4-dione
CBNumber: CB3273506
Molecular Formula: C16H16O5
Formula Weight: 288.3
MOL File: 54952-43-1.mol

Less

Shikalkin Property

Melting point:: 144-145 °C
Boiling point:: 567.4±50.0 °C(Predicted)
Density: 1.373±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: methanol: soluble1mg/mL
form: powder or solid
pka: 7.34±0.20(Predicted)
color: red to brown
LogP: 4.350 (est)

Less

Safety

Hazard Codes: Xn,N
Risk Statements: 22-50/53
Safety Statements: 61
RIDADR: UN 3077 9 / PGIII
WGK Germany: 3

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S7576
Product name: Shikonin
Purity: ≥98% (HPLC)
Packaging: 10mg
Price: $473
Updated: 2024/03/01

Sigma-Aldrich

Product number: S7576
Product name: Shikonin
Purity: ≥98% (HPLC)
Packaging: 50mg
Price: $1620
Updated: 2024/03/01

TRC

Product number: S357605
Product name: (±)-Shikonin
Packaging: 5mg
Price: $85
Updated: 2021/12/16

AK Scientific

Product number: 0282AQ
Product name: Shikonin
Packaging: 10mg
Price: $162
Updated: 2021/12/16

Arctom

Product number: SY232843
Product name: (±)-Shikonin
Purity: ≥98%
Packaging: 10mg
Price: $74.45
Updated: 2021/12/16

Less

Shikalkin Chemical Properties,Usage,Production

Uses

Shikonin has been used:

to enhance the anti-tumor activity of gefitinib on tyrosine kinase receptor epidermal growth factor receptor (EGFR) in wild-type lung cancer cells
as an inhibitor of renal aerobic glycosis and a potential
as an anti-inflammatory agent to test its role to improve lipopolysaccharide (LPS)-induced cardiac dysfunction
to stimulate bone marrow-derived macrophages (BMDMs) to test the effect of Interferon regulatory factor 1 on cell death

Definition

ChEBI: C.I. Natural Red 20 is a naphthoquinone.

General Description

Shikonin is a major phytochemical compound extracted from the roots of Lithospermum erythrorhizon. It is a natural anthraquinone derivative.

Biochem/physiol Actions

Shikonin is a potent anti-fungal agent against C. albicans biofilms. It displays anti-oxidant and chemotherapeutic properties on human glioma cells.

Shikalkin Preparation Products And Raw materials

Raw materials

Preparation Products

Less

Shikalkin Suppliers

China 52 Japan 2 United Kingdom 1 United States 8 USA 1 Global 64

Nantong Feiyu Biological Technology CO.,LTD

Tel: 0513-68819626; 13813788405
Fax: 0513-68669626
Email: feiyubio2@163.com
Country: China
ProdList: 4821
Advantage: 58

Chengdu Climax Biotech Co., Ltd.

Tel: 028-83311324 1278112614
Fax: 028-83311324
Email: climaxbiotech@gmail.com
Country: China
ProdList: 925
Advantage: 58

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15185
Advantage: 58

AdooQ Bioscience CHINA

Tel: 025-58849295 18951903616;
Fax: 025-68650336
Email: info@adooq.cn
Country: China
ProdList: 2989
Advantage: 60

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51471
Advantage: 80

ATK CHEMICAL COMPANY LIMITED

Tel: 3429815786 13301662590
Fax: +86-21-51619052
Email: sales@atkchemical.com
Country: China
ProdList: 10006
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9709
Advantage: 58

Shandong Xiya Chemical Co., Ltd.

Tel: 4009903999 13395398332
Fax: 0539-6365991
Email: sales@xiyashiji.com
Country: China
ProdList: 20810
Advantage: 60

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12308
Advantage: 58

Chengdu Push Bio-Technology Co., Ltd.

Tel: 028-85370565-229 18080489829
Email: 3004654993@qq.com
Country: China
ProdList: 9175
Advantage: 60

Amatek Scientific Co. Ltd.

Tel: 0512-56316828
Fax: 0512-56316826
Email: info@amateksci.com
Country: China
ProdList: 28821
Advantage: 58

Beijing OKA biological technology co., LTD

Tel: 010-010-62971590 18548936886
Fax: 010-62340519
Email: 3462612863@qq.com
Country: China
ProdList: 6912
Advantage: 58

Wuhan ChemNorm Biotech Co.,Ltd.

Tel: +86-27-8439 4403 18971486879
Fax: +86-27-8439 4403
Email: sales@chemnorm.com
Country: CHINA
ProdList: 2935
Advantage: 58

Chengdu Peter-like Biotechnology Co., Ltd.

Tel: 028-81700200 18108052721
Email: 2850505130@qq.com
Country: China
ProdList: 5182
Advantage: 58

Shanghai Standard Technology Co., Ltd.

Tel: 18502101150
Fax: +86-21-57127007-6606
Email: ft-sales@nature-standard.com
Country: CHINA
ProdList: 1923
Advantage: 58

Chengdu Alfa Biotechnology Co.,Ltd.

Tel: 028-028-85142057 19983342022
Fax: 028-85142057
Email: 3005359975@qq.com
Country: China
ProdList: 1960
Advantage: 58

Guangzhou Younan Technology Co., Ltd

Tel: 020-020-82000279 18988968278
Fax: QQ：3283937693
Email: sales@ubiochem.com
Country: China
ProdList: 2357
Advantage: 58

Absin Bioscience Inc.

Tel: 021-38015121 15000105423
Email: chenjw@absin.cn
Country: China
ProdList: 24734
Advantage: 58

Nanjing shengyilai Chemical Co., Ltd

Tel: 19951936396
Email: 3158688292@qq.com
Country: China
ProdList: 4840
Advantage: 58

Wuxi Helen Biotechnology Co., Ltd.,

Tel: 0510-85629785 18013409632
Fax: 0510-85625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 14092
Advantage: 58

Wuhan ChemNorm co., LTD.

Tel: 18971486879
Email: 279414929@qq.com
Country: CHINA
ProdList: 2925
Advantage: 58

Shanghai Hewu Biotechnology Co., LTD

Tel: 021-57886085 17317861055
Email: shhebio@126.com
Country: CHINA
ProdList: 7975
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44941
Advantage: 58

Nanjing Bencao Yikang Biotechnology Co., Ltd

Tel: +86-025-69790911 18362932668
Email: 522593521@qq.com
Country: China
ProdList: 1163
Advantage: 58

Changzhou Furuisi Biotechnology Co., Ltd

Tel: 0519-85524369
Email: 3477467573@qq.com
Country: China
ProdList: 8618
Advantage: 58

Shaanxi Dideu Medichem Co. Ltd

Tel: 029-81124267 15229202216
Fax: 029-88380327
Email: 1073@dideu.com
Country: China
ProdList: 10011
Advantage: 58

Chengdu Push Bio-Technology Co., Ltd.

Tel: 18080489829
Email: 3004654993@qq.com
Country: China
ProdList: 9209
Advantage: 58

Shanghai Moqi Biological Technology Co., LTD

Tel: 021-38218169 13341702378
Email: 190129269@qq.com
Country: China
ProdList: 9111
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24024
Advantage: 58

Aikon International Limited

Tel: 18626450290
Email: yftan@aikonchem.com
Country: China
ProdList: 10718
Advantage: 58

Shanghai Maclean Biochemical Technology Co., LTD

Tel: 021-50706066 15221275939
Email: shenlinxing@macklin.cn
Country: China
ProdList: 29803
Advantage: 58

Naturewill Biotechnology Co., Ltd.

Tel: 18113192475 18113192475
Email: 3157321941@qq.com
Country: China
ProdList: 5000
Advantage: 58

ShenZhen Trendseen Biological Technology Co.,Ltd.

Tel: 13417589054 13417589054
Email: trendseenbio@gmail.com
Country: China
ProdList: 8941
Advantage: 58

Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 025-85560043 15850508050
Fax: 025-85563444
Email: rose.shi@synzest.com
Country: China
ProdList: 6111
Advantage: 58

Shanghai Aladdin Biochemical Technology Co.,Ltd.

Tel: +86-18521732826
Email: market@aladdin-e.com
Country: China
ProdList: 48518
Advantage: 58

Wuhan Huangzhen Biochemical Co., Ltd

Tel: 13795480948 13795480948
Email: 3450865996@qq.com
Country: China
ProdList: 4958
Advantage: 58

LEAPCHEM CO., LTD.

Tel: +86-852-30606658
Email: market18@leapchem.com
Country: China
ProdList: 43348
Advantage: 58

Shaanxi Haibo Biotechnology Co., Ltd

Tel: +undefined18602966907
Email: qinhe02@xaltbio.com
Country: China
ProdList: 1000
Advantage: 58

ShenZhen Trendseen Biological Technology Co.,Ltd.

Tel: 13417589054
Email: trendseenbio@gmail.com
Country: China
ProdList: 11681
Advantage: 58

Shaanxi Cuikang Pharmaceutical Technology Co., Ltd

Tel: +8618829768577
Email: gao490372054@gamil.com
Country: China
ProdList: 1250
Advantage: 58

Henan Allgreen Chemical Co.,LTD

Tel: +86-37155567971 +86-13633837469
Email: info@allgreenchem.com
Country: China
ProdList: 5986
Advantage: 58

ZHEJIANG JIUZHOU CHEM CO., LTD

Tel: +86-0576225566889 +86-13454675544
Email: admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com
Country: China
ProdList: 20000
Advantage: 58

Nanjing Doge Biomedical Technology Co., Ltd

Tel: +86-25-58227606 +86-15305155328
Email: sales@dogechemical.com
Country: China
ProdList: 4128
Advantage: 58

Shanghai Humin Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: 869248833@qq.com
Country: CHINA
ProdList: 6147
Advantage: 58

Shanghai Hao Zhun Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: info@zzsrm.com
Country: CHINA
ProdList: 6846
Advantage: 58

Xiamen Research Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 1562893815@qq.com
Country: CHINA
ProdList: 6942
Advantage: 58

Shanghai Ziqi Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: 2453006496@qq.com
Country: CHINA
ProdList: 6192
Advantage: 58

Xiamen Huijia Biological Technology Co., Ltd.

Tel: --
Fax: --
Country: CHINA
ProdList: 6979
Advantage: 58

Less

View Lastest Price from Shikalkin manufacturers

Shaanxi Haibo Biotechnology Co., Ltd

Product: Shikalkin 54952-43-1
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000ton
Release date: 2023-08-29

Shanghai Standard Technology Co., Ltd.

Product: Shikalkin 54952-43-1
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-09-16

54952-43-1, ShikalkinRelated Search:

2,6-DIMETHYLNAPHTHALENE ACETYLSHIKONIN Naphthalene Dextran Methyl cyclopentenolone Allethrin Allyl methacrylate CHLOROPHOSPHONAZO III Alkannin 2-Methylnaphthalene Iron-dextran D(+)-Glucose METHYLCYCLOPENTADIENE DIMER 6-Methyl-5-hepten-2-one griffonin lithospermic acid Dihydroechinofuran DIHYDRO CUMINYL ALCOHOL

5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-enyl)naphthalene-1,4-dione

SHIKALKIN

1,4-Naphthalenedione, 5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)- (9ci)

Arnebin-4

Nsc 291845

shiconin

Shikonin (mixture of optical isomers, about 1:1)

1,4-Naphthalenedione, 5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-penten-1-yl)-

Shikonin >=98% (HPLC)

(+-)-Shikonin

(Rac)-Shikonin

5,8-dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)naphthalene-1,4-dione

Inhibitor,inhibit,Shikalkin,(Rac) Shikonin,(Rac)Shikonin,(Rac)-Shikonin

54952-43-1

Inhibitors

Coronavirus