ChemicalBook > CAS DataBase List > Shikalkin
Shikalkin
- Product Name
- Shikalkin
- CAS No.
- 54952-43-1
- Chemical Name
- Shikalkin
- Synonyms
- shiconin;Arnebin-4;SHIKALKIN;Nsc 291845;(+-)-Shikonin;(Rac)-Shikonin;Shikonin >=98% (HPLC);Shikonin (mixture of optical isomers, about 1:1);5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-enyl)naphthalene-1,4-dione;5,8-dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)naphthalene-1,4-dione
- CBNumber
- CB3273506
- Molecular Formula
- C16H16O5
- Formula Weight
- 288.3
- MOL File
- 54952-43-1.mol
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Shikalkin Property
- Melting point:
- 144-145 °C
- Boiling point:
- 567.4±50.0 °C(Predicted)
- Density
- 1.373±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- methanol: soluble1mg/mL
- form
- powder or solid
- pka
- 7.34±0.20(Predicted)
- color
- red to brown
- LogP
- 4.350 (est)
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- S7576
- Product name
- Shikonin
- Purity
- ≥98% (HPLC)
- Packaging
- 10mg
- Price
- $473
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- S7576
- Product name
- Shikonin
- Purity
- ≥98% (HPLC)
- Packaging
- 50mg
- Price
- $1620
- Updated
- 2024/03/01
TRC
- Product number
- S357605
- Product name
- (±)-Shikonin
- Packaging
- 5mg
- Price
- $85
- Updated
- 2021/12/16
AK Scientific
- Product number
- 0282AQ
- Product name
- Shikonin
- Packaging
- 10mg
- Price
- $162
- Updated
- 2021/12/16
Arctom
- Product number
- SY232843
- Product name
- (±)-Shikonin
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $74.45
- Updated
- 2021/12/16
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Shikalkin Chemical Properties,Usage,Production
Uses
Shikonin has been used:
- to enhance the anti-tumor activity of gefitinib on tyrosine kinase receptor epidermal growth factor receptor (EGFR) in wild-type lung cancer cells
- as an inhibitor of renal aerobic glycosis and a potential
- as an anti-inflammatory agent to test its role to improve lipopolysaccharide (LPS)-induced cardiac dysfunction
- to stimulate bone marrow-derived macrophages (BMDMs) to test the effect of Interferon regulatory factor 1 on cell death
Definition
ChEBI: C.I. Natural Red 20 is a naphthoquinone.
General Description
Shikonin is a major phytochemical compound extracted from the roots of Lithospermum erythrorhizon. It is a natural anthraquinone derivative.
Biochem/physiol Actions
Shikonin is a potent anti-fungal agent against C. albicans biofilms. It displays anti-oxidant and chemotherapeutic properties on human glioma cells.
Shikalkin Preparation Products And Raw materials
Raw materials
Preparation Products
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Shikalkin Suppliers
- Tel
- --
- Fax
- --
- info-tech@nacalai.co.jp
- Country
- Japan
- ProdList
- 6046
- Advantage
- 75
- Tel
- --
- Fax
- --
- labchem-tec@wako-chem.co.jp
- Country
- Japan
- ProdList
- 6819
- Advantage
- 80
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View Lastest Price from Shikalkin manufacturers
Shaanxi Haibo Biotechnology Co., Ltd
- Product
- Shikalkin 54952-43-1
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 2000ton
- Release date
- 2023-08-29
Shanghai Standard Technology Co., Ltd.
- Product
- Shikalkin 54952-43-1
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2019-09-16
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