indanol dehydrogenase
Description Source Background- Product Name
- indanol dehydrogenase
- CAS No.
- 55976-95-9
- Chemical Name
- indanol dehydrogenase
- Synonyms
- DDX;DD3;PGFS;HAKRB;HAKRe;HA1753;AKR1C3;hluPGFS;KIAA0119;AKR1C3 human
- CBNumber
- CB81349285
- Formula Weight
- 0
- MOL File
- Mol file
indanol dehydrogenase Property
- storage temp.
- -70°C
- form
- liquid
- Specific Activity
- ≥0.4μmol/mg protein
Safety
- WGK Germany
- 1
N-Bromosuccinimide Price
- Product number
- F7807
- Product name
- Prostaglandin F Synthase human
- Purity
- recombinant, expressed in E. coli, ≥90% (SDS-PAGE)
- Packaging
- 50μg
- Price
- $492
- Updated
- 2025/07/31
- Product number
- orb595312
- Product name
- AKR1C3
- Packaging
- 10μg
- Price
- $290.7
- Updated
- 2021/12/16
- Product number
- orb595311
- Product name
- AKR1C3
- Packaging
- 10μg
- Price
- $290.7
- Updated
- 2021/12/16
indanol dehydrogenase Chemical Properties,Usage,Production
Uses
Prostaglandin F synthase (PGF synthase) is a member of the aldo-keto reductase superfamily of proteins which catalyze the conversion of aldehydes and ketones to thier corresponding alcohols. Prostaglandin F synthase is used in cancer research since it is upregulated in many cancers such as breast and prostate cancer. PGF synthase is also used to study kidney and renal cell carcinoma .
Biological Activity
PGF synthase catalyzes the conversions of 4-androstene-3,17-dione to testosterone, estrone to 17β-estradiol, prostaglandin H2 to PGF2α, and PGD2 to 9α,11β-PGF2. Prostaglandin (PG) F2 is synthesized via three pathways .
Description
AKR1C3 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 323 amino acids (1-323) and having a molecular mass of 36.8 kDa.
AKR1C3 is purified by proprietary chromatographic techniques.
Source
Escherichia Coli
Background
Aldo-keto reductase family 1 member C3 isoform 1 or AKR1C3 is an enzyme, part of the aldo-keto reductase family that promotes conversion of ketones & aldehydes to the alcohol forms while using cofactors such as NADPH & NADH. AKR1C3 promotes the reduction of PG molecule (prostaglandin), PQ (phenanthrenequinone) & PGH2. Another role is oxidation of 9 alpha, 11 beta-PGF2 to PGD2. AKR1C3 holds a crucial part in the pathogenesis of allergic diseases like asthma and can also take part in the regulation of cell growth and differentiation.
indanol dehydrogenase Preparation Products And Raw materials
Raw materials
Preparation Products
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