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indanol dehydrogenase

Description Source Background
Product Name
indanol dehydrogenase
CAS No.
55976-95-9
Chemical Name
indanol dehydrogenase
Synonyms
DDX;DD3;PGFS;HAKRB;HAKRe;HA1753;AKR1C3;hluPGFS;KIAA0119;AKR1C3 human
CBNumber
CB81349285
Formula Weight
0
MOL File
Mol file
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indanol dehydrogenase Property

storage temp. 
-70°C
form 
liquid
Specific Activity
≥0.4μmol/mg protein
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Safety

WGK Germany 
1
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
F7807
Product name
Prostaglandin F Synthase human
Purity
recombinant, expressed in E. coli, ≥90% (SDS-PAGE)
Packaging
50μg
Price
$492
Updated
2025/07/31
Biorbyt Ltd
Product number
orb595312
Product name
AKR1C3
Packaging
10μg
Price
$290.7
Updated
2021/12/16
Biorbyt Ltd
Product number
orb595311
Product name
AKR1C3
Packaging
10μg
Price
$290.7
Updated
2021/12/16
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indanol dehydrogenase Chemical Properties,Usage,Production

Uses

Prostaglandin F synthase (PGF synthase) is a member of the aldo-keto reductase superfamily of proteins which catalyze the conversion of aldehydes and ketones to thier corresponding alcohols. Prostaglandin F synthase is used in cancer research since it is upregulated in many cancers such as breast and prostate cancer. PGF synthase is also used to study kidney and renal cell carcinoma .

Biological Activity

PGF synthase catalyzes the conversions of 4-androstene-3,17-dione to testosterone, estrone to 17β-estradiol, prostaglandin H2 to PGF2α, and PGD2 to 9α,11β-PGF2. Prostaglandin (PG) F2 is synthesized via three pathways .

Description

AKR1C3 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 323 amino acids (1-323) and having a molecular mass of 36.8 kDa.
AKR1C3 is purified by proprietary chromatographic techniques.

Source

Escherichia Coli

Background

Aldo-keto reductase family 1 member C3 isoform 1 or AKR1C3 is an enzyme, part of the aldo-keto reductase family that promotes conversion of ketones & aldehydes to the alcohol forms while using cofactors such as NADPH & NADH. AKR1C3 promotes the reduction of PG molecule (prostaglandin), PQ (phenanthrenequinone) & PGH2. Another role is oxidation of 9 alpha, 11 beta-PGF2 to PGD2. AKR1C3 holds a crucial part in the pathogenesis of allergic diseases like asthma and can also take part in the regulation of cell growth and differentiation.

indanol dehydrogenase Preparation Products And Raw materials

Raw materials

Preparation Products

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indanol dehydrogenase Suppliers

Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4720
Advantage
55
Shanghai Han-Xiang Chemical Co., Ltd.
Tel
15971444841
Fax
18327183813
Email
amber@biochempartner.com
Country
China
ProdList
3061
Advantage
58
Guangzhou Tomums Life Science Co., Ltd.
Tel
020-31155029 18902330969
Fax
020-31155029
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sales@tomums.cn
Country
China
ProdList
4696
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Wuhan Chemstan Biotechnology Co., Ltd.
Tel
027-65317797 15926423062
Fax
QQ:422450190
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422450190@qq.com
Country
China
ProdList
10308
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Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
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China
ProdList
44918
Advantage
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Merck KGaA
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21-20338288
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ordercn@merckgroup.com
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Cellosaurus STR
Tel
13121892008
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cellosaurus@sib.swiss
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Signalway Antibody LLC
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025-58868422
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Elabscience Biotechnology Co Ltd
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400999210
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marketing@elabscience.cn
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Beijing Biosynthesis Biotechnology Co Ltd
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400-9019800
Email
sales@bioss.com.cn
Country
China
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6102
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55976-95-9, indanol dehydrogenaseRelated Search:


  • indanol dehydrogenase
  • 17-beta-hydroxysteroid dehydrogenase type 5
  • AKR1C3
  • aldo-keto reductase family 1 member C3
  • Prostaglandin F Synthase human
  • AKR1C3 human
  • DD3
  • DDX
  • HA1753
  • HAKRB
  • Prostaglandin F Synthase from human, Recombinant
  • Prostaglandin F Synthase human recombinant, expressed in E. coli, >=90% (SDS-PAGE)
  • Recombinant Human AKR1C3 Protein, His Tag
  • HAKRe
  • hluPGFS
  • KIAA0119
  • PGFS
  • 55976-95-9