NQ301

Product Name: NQ301
CAS No.: 130089-98-4
Chemical Name: NQ301
Synonyms: NQ301;NQ 301; NQ-301;NQ301 >=98% (HPLC);NQ301 - Compound 211;inhibit,Inhibitor,NQ-301,NQ301,NQ 301,Thrombin;2-(4-Acetylanilino)-3-chloronaphthalene-1,4-dione;2-((4-acetylphenyl)amino)-3-chloronaphthalene-1,4-dione;2-[(4-Acetylphenyl)amino]-3-chloro-1,4-naphthalenedione;1,4-Naphthalenedione, 2-[(4-acetylphenyl)amino]-3-chloro-
CBNumber: CB81352274
Molecular Formula: C18H12ClNO3
Formula Weight: 325.75
MOL File: 130089-98-4.mol

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NQ301 Property

Melting point:: 241-243 °C(Solv: ethanol (64-17-5))
Boiling point:: 476.8±45.0 °C(Predicted)
Density: 1.40±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO:10.0(Max Conc. mg/mL);30.7(Max Conc. mM)
form: powder
pka: -5.25±0.20(Predicted)
color: faint red to dark red

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Safety

RIDADR: UN 3077 9 / PGIII

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

P391Collect spillage. Hazardous to the aquatic environment

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1337
Product name: NQ301
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $118
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML1337
Product name: NQ301
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $370
Updated: 2024/03/01

Cayman Chemical

Product number: 21958
Product name: NQ301
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 21958
Product name: NQ301
Packaging: 5mg
Price: $100
Updated: 2024/03/01

Cayman Chemical

Product number: 21958
Product name: NQ301
Packaging: 10mg
Price: $139
Updated: 2024/03/01

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NQ301 Chemical Properties,Usage,Production

Uses

NQ 301 possess antiplatelet effect, making it an antithrombotic agent. It significantly inhibited the collagen-?, thrombin-?, arachidonic acid-?, thapsigargin- and calcium ionophore A23187-?induced aggregation of washed human platelets.

Biochem/physiol Actions

NQ301 is an antithrombotic agent. Recent study shows that NQ301 (Compound 211) is a highly potent, selective, non-competitive allosteric inhibitor of CD45 that selectively inhibits dephosphorylation of substrate Lck pY-505 versus Lck pY-393. NQ301 prevents T cell receptor-mediated activation of Lck, Zap-70 and MAPK, and IL-2 production in primary T-cells. NQ301 exhibits immunosuppressive activity in mice.

NQ301 Preparation Products And Raw materials

Raw materials

Preparation Products

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NQ301 Suppliers

China 52 United Kingdom 1 United States 9 Global 62

BOC Sciences

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Sigma-Aldrich

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Shanghai Chaolan Chemical Technology Center

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Angel Pharmatech, Ltd.

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130089-98-4, NQ301Related Search:

NQ301

NQ301 - Compound 211

NQ 301; NQ-301

2-((4-acetylphenyl)amino)-3-chloronaphthalene-1,4-dione

2-(4-Acetylanilino)-3-chloronaphthalene-1,4-dione

2-[(4-Acetylphenyl)amino]-3-chloro-1,4-naphthalenedione

1,4-Naphthalenedione, 2-[(4-acetylphenyl)amino]-3-chloro-

NQ301 >=98% (HPLC)

inhibit,Inhibitor,NQ-301,NQ301,NQ 301,Thrombin

130089-98-4