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napyradiomycin A1

Product Name
napyradiomycin A1
CAS No.
103106-24-7
Chemical Name
napyradiomycin A1
Synonyms
WS-9558A;Napyradiomycin A;napyradiomycin A1;3,4a-Dichloro-6,8-dihydroxy-3,4,4a,10a-tetrahydro-2,2-dimethyl-10a-(3,7-dimethyl-2,6-octadienyl)-2H-naphtho[2,3-b]pyran-5,10-dione;2H-Naphtho[2,3-b]pyran-5,10-dione, 3,4a-dichloro-10a-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-3,4,4a,10a-tetrahydro-6,8-dihydroxy-2,2-dimethyl-, (3R,4aR,10aS)-
CBNumber
CB81373343
Molecular Formula
C25H30Cl2O5
Formula Weight
481.413
MOL File
103106-24-7.mol
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napyradiomycin A1 Property

Boiling point:
642.5±55.0 °C(Predicted)
Density 
1.31±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Dichloromethane: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
form 
A solid
pka
6.14±0.70(Predicted)
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Safety

HS Code 
29419000
Toxicity
mouse,LD50,intraperitoneal,> 250mg/kg (250mg/kg),Journal of Antibiotics. Vol. 39, Pg. 487, 1986.
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
29215
Product name
Napyradiomycin A1
Packaging
1mg
Price
$189
Updated
2024/03/01
TRC
Product number
N378705
Product name
NapyradiomycinA1
Packaging
1mg
Price
$165
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0013137
Product name
NAPYRADIOMYCIN A
Purity
95.00%
Packaging
5MG
Price
$505.67
Updated
2021/12/16
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napyradiomycin A1 Chemical Properties,Usage,Production

Description

Napyradiomycin A1 is a fungal metabolite originally isolated from C. rubra and has diverse biological activities. It is active against S. aureus, M. luteus, B. anthracis, C. bovis, and M. smegmatis (MICs = 1.56-12.5 μg/ml). Napyradiomycin A1 is an estrogen receptor antagonist (IC50 = 4.2 μM in rat uterine homogenates). It also inhibits mitochondrial NADH:ubiquinone oxidoreductase (complex I) and succinate:ubiquinone oxidoreductase (complex II) activities in bovine heart homogenates (IC50s = 20 and 9.7 μM, respectively).

Uses

Napyradiomycin derivatives have antibacterial and tumor properties. Napyradiomycin A1 is a secondary metabolite isolated from Streptomyces. It is also an antibacterial antibiotic and an inhibitor of mitochondrial complexes I and II.

Definition

ChEBI: Napyradiomycin A1 is a member of menaquinones.

napyradiomycin A1 Preparation Products And Raw materials

Raw materials

Preparation Products

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napyradiomycin A1 Suppliers

China 7 Germany 1 United Kingdom 1 United States 3 Global 12
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14055
Advantage
65
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32063
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11217
Advantage
58
Zhejiang Huida Biotech Co., LTD
Tel
0571-89903882 13626641628
Email
jiangnan@huidabiotech.com
Country
China
ProdList
3656
Advantage
58
Changzhou Furuisi Biotechnology Co., Ltd
Tel
0519-85524369
Email
3477467573@qq.com
Country
China
ProdList
8617
Advantage
58
Zhejiang Huida Biotech Co., LTD
Tel
0571-0571-89903882 15990081639
Email
sunshixuan@huidabiotech.com
Country
China
ProdList
3705
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24648
Advantage
58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
11974
Advantage
58
Guangzhou Yaoguang Technology Co., Ltd.
Tel
13020159086
Email
yangjue@ygfuture.com
Country
China
ProdList
621
Advantage
58

103106-24-7, napyradiomycin A1Related Search:

5-Hydroxy-1-tetralone 2,2'-Dichlorodiethyl ether Geranylacetone 4-Hexanoylresorcinol 2-Methyl-1-tetralone GAMMA-CHLOROBUTYROPHENONE 2',4'-Dichlorovalerophenone 4-CHLORO-4'-HYDROXYBUTYROPHENONE 2-Chloro-2',4'-dihydroxyacetophenone 3-Chloropropiophenone 2-CHLORO-4'-HYDROXYACETOPHENONE 4-Chlorovalerophenone 5-CHLORO-1-(2-METHYLPHENYL)-1-OXOPENTANE SCYTALONE 3-CHLORO-2-METHYL-2-BUTANOL 4-CHLORO-1-(2-METHYLPHENYL)-1-OXOBUTANE 5-chloro-1-phenylpentan-1-one napyradiomycin C1

  • napyradiomycin A1
  • 3,4a-Dichloro-6,8-dihydroxy-3,4,4a,10a-tetrahydro-2,2-dimethyl-10a-(3,7-dimethyl-2,6-octadienyl)-2H-naphtho[2,3-b]pyran-5,10-dione
  • Napyradiomycin A
  • WS-9558A
  • 2H-Naphtho[2,3-b]pyran-5,10-dione, 3,4a-dichloro-10a-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-3,4,4a,10a-tetrahydro-6,8-dihydroxy-2,2-dimethyl-, (3R,4aR,10aS)-
  • 103106-24-7
  • C25H30Cl2O5
  • Antibiotic