napyradiomycin A1

Product Name: napyradiomycin A1
CAS No.: 103106-24-7
Chemical Name: napyradiomycin A1
Synonyms: WS-9558A;Napyradiomycin A;napyradiomycin A1;3,4a-Dichloro-6,8-dihydroxy-3,4,4a,10a-tetrahydro-2,2-dimethyl-10a-(3,7-dimethyl-2,6-octadienyl)-2H-naphtho[2,3-b]pyran-5,10-dione;2H-Naphtho[2,3-b]pyran-5,10-dione, 3,4a-dichloro-10a-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-3,4,4a,10a-tetrahydro-6,8-dihydroxy-2,2-dimethyl-, (3R,4aR,10aS)-
CBNumber: CB81373343
Molecular Formula: C25H30Cl2O5
Formula Weight: 481.413
MOL File: 103106-24-7.mol

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napyradiomycin A1 Property

Boiling point:: 642.5±55.0 °C(Predicted)
Density: 1.31±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Dichloromethane: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
form: A solid
pka: 6.14±0.70(Predicted)

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Safety

HS Code: 29419000
Toxicity: mouse,LD50,intraperitoneal,> 250mg/kg (250mg/kg),Journal of Antibiotics. Vol. 39, Pg. 487, 1986.

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 29215
Product name: Napyradiomycin A1
Packaging: 1mg
Price: $189
Updated: 2024/03/01

TRC

Product number: N378705
Product name: NapyradiomycinA1
Packaging: 1mg
Price: $165
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0013137
Product name: NAPYRADIOMYCIN A
Purity: 95.00%
Packaging: 5MG
Price: $505.67
Updated: 2021/12/16

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napyradiomycin A1 Chemical Properties,Usage,Production

Description

Napyradiomycin A₁ is a fungal metabolite originally isolated from C. rubra and has diverse biological activities. It is active against S. aureus, M. luteus, B. anthracis, C. bovis, and M. smegmatis (MICs = 1.56-12.5 μg/ml). Napyradiomycin A₁ is an estrogen receptor antagonist (IC₅₀ = 4.2 μM in rat uterine homogenates). It also inhibits mitochondrial NADH:ubiquinone oxidoreductase (complex I) and succinate:ubiquinone oxidoreductase (complex II) activities in bovine heart homogenates (IC₅₀s = 20 and 9.7 μM, respectively).

Uses

Napyradiomycin derivatives have antibacterial and tumor properties. Napyradiomycin A1 is a secondary metabolite isolated from Streptomyces. It is also an antibacterial antibiotic and an inhibitor of mitochondrial complexes I and II.

Definition

ChEBI: Napyradiomycin A1 is a member of menaquinones.

napyradiomycin A1 Preparation Products And Raw materials

Raw materials

Preparation Products

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napyradiomycin A1 Suppliers

China 7 Germany 1 United Kingdom 1 United States 3 Global 12

Apollo Scientific Ltd.

Tel: --
Fax: --
Email: sales@apolloscientific.co.uk
Country: United Kingdom
ProdList: 6084
Advantage: 88

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napyradiomycin A1

3,4a-Dichloro-6,8-dihydroxy-3,4,4a,10a-tetrahydro-2,2-dimethyl-10a-(3,7-dimethyl-2,6-octadienyl)-2H-naphtho[2,3-b]pyran-5,10-dione

Napyradiomycin A

WS-9558A

2H-Naphtho[2,3-b]pyran-5,10-dione, 3,4a-dichloro-10a-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-3,4,4a,10a-tetrahydro-6,8-dihydroxy-2,2-dimethyl-, (3R,4aR,10aS)-

103106-24-7

C25H30Cl2O5

Antibiotic