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kakkalide

Product Name
kakkalide
CAS No.
58274-56-9
Chemical Name
kakkalide
Synonyms
kakkalide;CID 14037245;kakkalide USP/EP/BP;Kakkalide,Inhibitor,inhibit;4H-1-Benzopyran-4-one, 5-hydroxy-6-methoxy-3-(4-methoxyphenyl)-7-[(6-O-β-D-xylopyranosyl-β-D-glucopyranosyl)oxy]-;5-Hydroxy-6-methoxy-3-(4-methoxyphenyl)-7-[(6-O-beta-D-xylopyranosyl-beta-D-glucopyranosyl)oxy]-4H-1-benzopyran-4-one;5-Hydroxy-6-methoxy-3-(4-methoxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one
CBNumber
CB81377280
Molecular Formula
C28H32O15
Formula Weight
608.54
MOL File
58274-56-9.mol
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kakkalide Property

Melting point:
250-252 °C
Boiling point:
902.0±65.0 °C(Predicted)
Density 
1?+-.0.1 g/cm3(Predicted)
pka
6.08±0.20(Predicted)
form 
Solid
color 
White to off-white
LogP
-0.292 (est)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
PXT0003486
Product name
KAKKALIDE
Purity
95.00%
Packaging
5MG
Price
$500.37
Updated
2021/12/16
ChemScene
Product number
CS-0032520
Product name
Kakkalide
Packaging
5mg
Price
$504
Updated
2021/12/16
ChemScene
Product number
CS-0032520
Product name
Kakkalide
Packaging
10mg
Price
$857
Updated
2021/12/16
Arctom
Product number
CFN95052
Product name
Kakkalide
Packaging
10mg
Price
$260
Updated
2021/12/16
Arctom
Product number
SY232560
Product name
kakkalide
Purity
≥95%
Packaging
10mg
Price
$441.82
Updated
2021/12/16
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kakkalide Chemical Properties,Usage,Production

Uses

Kakkalide is an isoflavone derived from the flowers of Pueraria lobata. Kakkalide ameliorates endothelial insulin resistance by suppressing reactive oxygen species (ROS)-associated inflammation[1].

Synthesis

Kudzu flowers were crushed and weighed 300g, respectively, extracted with 900 mL of methanol in cold soak for three times, and the combined extracts were concentrated under reduced pressure. The methanol extract was suspended in appropriate amount of distilled water, firstly extracted with benzene to degrease, then extracted with n-butanol, the n-butanol extract was concentrated to dryness, eluted by silica gel column chromatography with CHCl3:CH3OH ( 10:1), and obtained light yellow snowflake crystals (methanol recrystallization), that is, to obtain the kudzuoside.

References

[1] Zhang D, et al. Kakkalide ameliorates endothelial insulin resistance by suppressing reactive oxygen species-associated inflammation. J Diabetes. 2013 Mar;5(1):13-24. DOI:10.1111/1753-0407.12017

kakkalide Preparation Products And Raw materials

Raw materials

Preparation Products

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kakkalide Suppliers

Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
Fax
+86-28-82633165
Email
cwb1@biopurify.cn
Country
China
ProdList
2376
Advantage
60
Shanghai Winherb Medical Technology Co., Ltd.
Tel
17301719108 13341702378
Fax
QQ:190129269
Email
winherb@126.com
Country
China
ProdList
1245
Advantage
58
Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Fax
0086-21-51320502
Email
tauto@tautobiotech.com
Country
China
ProdList
3988
Advantage
66
Cheng Du Pufeide Biotechnology Co., Ltd.
Tel
028-82610909 13388174823
Fax
8171-1798
Email
scglp@glp-china.com
Country
China
ProdList
1064
Advantage
58
Shanghai Aspire Biological Technology Co., Ltd.
Tel
021-61317773
Fax
021-61486878
Email
sales@aspirebio.com
Country
China
ProdList
2880
Advantage
58
Wuhan ChemFaces Biochemical Co., Ltd.
Tel
18607101326 15172504745
Fax
+86-27-84254680
Email
aileen@chemfaces.com
Country
China
ProdList
6905
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
Email
sales@xiyashiji.com
Country
China
ProdList
20794
Advantage
60
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Shanghai Yihe Biological Technology Co., Ltd.
Tel
021-68882955 17721395025
Email
2423903095@qq.com
Country
China
ProdList
5000
Advantage
58
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View Lastest Price from kakkalide manufacturers

Career Henan Chemical Co
Product
kakkalide 58274-56-9
Price
US $8.00/KG
Min. Order
1KG
Purity
>98% HPLC
Supply Ability
20 tons
Release date
2020-02-17

58274-56-9, kakkalideRelated Search:


  • kakkalide
  • 5-Hydroxy-6-methoxy-3-(4-methoxyphenyl)-7-[(6-O-beta-D-xylopyranosyl-beta-D-glucopyranosyl)oxy]-4H-1-benzopyran-4-one
  • 4H-1-Benzopyran-4-one, 5-hydroxy-6-methoxy-3-(4-methoxyphenyl)-7-[(6-O-β-D-xylopyranosyl-β-D-glucopyranosyl)oxy]-
  • kakkalide USP/EP/BP
  • 5-Hydroxy-6-methoxy-3-(4-methoxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one
  • Kakkalide,Inhibitor,inhibit
  • CID 14037245
  • 58274-56-9