progranulin
- Product Name
- progranulin
- Chemical Name
- progranulin
- Synonyms
- progranulin
- CBNumber
- CB81381968
- Formula Weight
- 0
- MOL File
- Mol file
N-Bromosuccinimide Price
- Product number
- P9007-34A
- Product name
- Progranulin
- Packaging
- 500ug
- Price
- $819
- Updated
- 2021/12/16
progranulin Chemical Properties,Usage,Production
Enzyme inhibitor
This 93-residue, cysteine-rich granulin precursor (MW = 88 kDa; Symbol: PGRN), also called proepithelin and PC cell-derived growth factor, is a pleiotrophic growth factor with important roles in maintaining and regulating the homeostatic dynamics of normal tissue development, proliferation, regeneration, and host-defense. PGRN also has potent antiinflammatory properties, and its deregulation is associated with rheumatoid arthritis and inflammatory bowel disease. Progranulin plays crucial roles in preserving bone mass by inhibiting TNF-α-induced osteoclastogenesis and promoting osteoblastic differentiation in mice. Recombinant PGRN protein strongly inhibits TNF and the expression of interferon-γ-induced chemokines CXCL9 and CXCL10. Moreover, in PGRNnull mice, many chemokines, including CXCL9 and CXCL10, are significantly induced.
progranulin Preparation Products And Raw materials
Raw materials
Preparation Products
progranulin Suppliers
- Tel
- 027-65279366 18108604356
- products@biolabreagent.com
- Country
- China
- ProdList
- 9868
- Advantage
- 58
- Tel
- 13121935750
- jiaxin.zhao@acrobiosystems.com
- Country
- China
- ProdList
- 1354
- Advantage
- 58
- Tel
- 420-549124185
- info@biovendor.com
- Country
- China
- ProdList
- 1266
- Advantage
- 58