polymyxin B(1)

Product Name: polymyxin B(1)
CAS No.: 4135-11-9
Chemical Name: polymyxin B(1)
Synonyms: polymyxin B(1);Polymyxin B1-[13C6,15N] TFA salt;Glucosamine Hydrochloride Impurity 33;polymyxin B1Q: What is polymyxin B1 Q: What is the CAS Number of polymyxin B1;(-)-N2-[[(6S)-6-Methyloctanoyl]-L-A2bu-L-Thr-L-A2bu-]cyclo(L-A2bu*-L-A2bu-D-Phe-L-Leu-L-A2bu-L-A2bu-L-Thr-);(S)-N-((S)-4-amino-1-(((2S,3R)-1-(((S)-4-amino-1-oxo-1-(((3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-((R)-1-hydroxyethyl)-12-isobutyl-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl)amino)butan-2-yl)amino)-3-hydroxy-1-oxobutan-2-yl)amino)-1-oxobutan-2-yl)-6-methyloctanamide;(6S)-N-[(2S)-4-amino-1-[[(2S,3R)-1-[[(2S)-4-amino-1-oxo-1-[[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-[(1R)-1-hydroxyethyl]-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxobutan-2-yl]-6-methyloctanamide
CBNumber: CB81388907
Molecular Formula: C56H98N16O13
Formula Weight: 1203.48
MOL File: 4135-11-9.mol

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polymyxin B(1) Property

Boiling point:: 838.79°C (rough estimate)
Density: 1.0500 (rough estimate)
refractive index: 1.6200 (estimate)
storage temp.: Store at -20°C
solubility: PBS (pH 7.2): 2 mg/ml
form: A crystalline solid
pka: 13.08±0.70(Predicted)
color: White to off-white
Sequence: {Dab(6-methyl-1-oxooctyl)}-Thr-{Dab}-{Dab}-{Dab}-{d-Phe}-Leu-{Dab}-{Dab}-Thr (Lactam bridge: Dab4-Thr10)
InChIKey: WQVJHHACXVLGBL-CTMZAJDNSA-N

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 14074
Product name: Polymyxin B1
Purity: ≥95%
Packaging: 1mg
Price: $120
Updated: 2024/03/01

Cayman Chemical

Product number: 14074
Product name: Polymyxin B1
Purity: ≥95%
Packaging: 5mg
Price: $477
Updated: 2024/03/01

Cayman Chemical

Product number: 14074
Product name: Polymyxin B1
Purity: ≥95%
Packaging: 10mg
Price: $759
Updated: 2024/03/01

American Custom Chemicals Corporation

Product number: API0013125
Product name: POLYMYXIN B(1)
Purity: 95.00%
Packaging: 1MG
Price: $225.75
Updated: 2021/12/16

ChemScene

Product number: CS-0019929
Product name: PolymyxinB1
Purity: ≥96.0%
Packaging: 1mg
Price: $450
Updated: 2021/12/16

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polymyxin B(1) Chemical Properties,Usage,Production

Uses

An antibacterial compound. It has a high volume of distribution and longer elimination half-life in patient with multidrug-resistant gram-negative bacterial infection.

Definition

ChEBI: A polymyxin having a (6R)-6-methyloctanoyl group at the amino terminus.

in vivo

The pharmacokinetics of Polymyxin B1 is investigated in a rat model following intravenous administration (0.8 mg/kg). The area under the concentration-time curve for Polymyxins B1 is greater than those of colistins A and B. Colistin A colistin B. The clearance value of Polymyxins B1 is 2.39 mL/min/kg, the plasma protein binding is 82.3%, the elimination half-life is 79.5 min and the AUC_0-∞ is 365 mg min/L^[5].

polymyxin B(1) Preparation Products And Raw materials

Raw materials

Preparation Products

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polymyxin B(1) Suppliers

Canada 1 China 58 India 1 South Korea 1 United States 8 Global 69

Heyuan broad spectrum Biotechnology Co., Ltd

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Shanghai Macklin Biochemical Co.,Ltd.

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Shanghai YuanYe Biotechnology Co., Ltd.

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Shanghai SuperLan Chemcial Technique Centre

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View Lastest Price from polymyxin B(1) manufacturers

Guangzhou PI PI BIOTECH INC

Product: Polymyxin B1 4135-11-9
Price: US $0.00-0.00/mg
Min. Order: 5mg
Purity: 85~95%
Supply Ability: 100mg
Release date: 2025-12-18

Shaanxi Dideu Medichem Co. Ltd

Product: polymyxin B(1) 4135-11-9
Price: US $1.00-60.00/KG
Min. Order: 1KG
Purity: 99%+
Supply Ability: 10086KG
Release date: 2024-05-17

4135-11-9, polymyxin B(1)Related Search:

Butyl stearate Bromothymol Blue CPNQ Vitamin B series

(6S)-N-[(2S)-4-amino-1-[[(2S,3R)-1-[[(2S)-4-amino-1-oxo-1-[[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-[(1R)-1-hydroxyethyl]-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxobutan-2-yl]-6-methyloctanamide

polymyxin B(1)

(-)-N2-[[(6S)-6-Methyloctanoyl]-L-A2bu-L-Thr-L-A2bu-]cyclo(L-A2bu*-L-A2bu-D-Phe-L-Leu-L-A2bu-L-A2bu-L-Thr-)

polymyxin B1Q: What is polymyxin B1 Q: What is the CAS Number of polymyxin B1

(S)-N-((S)-4-amino-1-(((2S,3R)-1-(((S)-4-amino-1-oxo-1-(((3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-((R)-1-hydroxyethyl)-12-isobutyl-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl)amino)butan-2-yl)amino)-3-hydroxy-1-oxobutan-2-yl)amino)-1-oxobutan-2-yl)-6-methyloctanamide

Polymyxin B1-[13C6,15N] TFA salt

Glucosamine Hydrochloride Impurity 33

4135-11-9

14135-11-9

C56H98N16O13