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CPNQ

Product Name
CPNQ
CAS No.
115687-05-3
Chemical Name
CPNQ
Synonyms
B2;CPNQ;SIRT2-IN-8;SIRT2 Inhibitor, B2;Linazolamide intermediate B impurity 2;5-[4-(4-Chlorobenzoyl)-1-piperazinyl]-8-nitroquinoline;(4-chlorophenyl)-[4-(8-nitroquinolin-5-yl)piperazin-1-yl]methanone;Methanone, (4-chlorophenyl)[4-(8-nitro-5-quinolinyl)-1-piperazinyl]-;Sirtuin,Parkinson’s diseases,Huntington’s diseases,Inhibitor,B2,inhibit,B-2
CBNumber
CB9972382
Molecular Formula
C20H17ClN4O3
Formula Weight
396.83
MOL File
115687-05-3.mol
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CPNQ Property

Melting point:
174-176°C
Boiling point:
645.5±55.0 °C(Predicted)
Density 
1.412±0.06 g/cm3(Predicted)
storage temp. 
Store at +4°C
solubility 
H2O: insoluble <2mg/mL
pka
2.30±0.29(Predicted)
form 
solid
color 
brown
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Safety

Hazard Codes 
T
Risk Statements 
25-36/37/38
Safety Statements 
26-45
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C3118
Product name
CPNQ
Purity
≥98% (HPLC), solid
Packaging
5mg
Price
$193
Updated
2024/03/01
Sigma-Aldrich
Product number
C3118
Product name
CPNQ
Purity
≥98% (HPLC), solid
Packaging
25mg
Price
$719
Updated
2021/12/16
TRC
Product number
B820015
Product name
B2
Packaging
1mg
Price
$200
Updated
2021/12/16
Usbiological
Product number
254701
Product name
B2
Packaging
10mg
Price
$403
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0008461
Product name
CPNQ
Purity
95.00%
Packaging
10MG
Price
$673.08
Updated
2021/12/16
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CPNQ Chemical Properties,Usage,Production

Uses

B2 is a cell permeable inhibitor of SIRT2 (sirtuin 2). Multidrug resistance protein 4 (MRP4) inhibitor in tumors such as neuroblastoma and colorectal cancer.

Definition

ChEBI: (4-chlorophenyl)-[4-(8-nitro-5-quinolinyl)-1-piperazinyl]methanone is a N-arylpiperazine.

Biological Activity

Promotes inclusion formation in cellular models of Huntington's disease and Parkinson's disease. Prevents huntingtin-mediated proteasome dysfunction and reduces α -synuclein-mediated toxicity.

CPNQ Preparation Products And Raw materials

Raw materials

Preparation Products

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CPNQ Suppliers

China 35 Switzerland 1 United Kingdom 1 United States 7 Global 44
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Zhengzhou Guancheng Laboratory equipment Sales
Tel
0371-88888888 272369594
Fax
QQ:272369594
Email
2723695949@qq.com
Country
China
ProdList
4866
Advantage
50
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
15076683720
Fax
022-23754520
Email
klq@cw-bio.com
Country
China
ProdList
4420
Advantage
55
Shanghai Rechem science Co., Ltd.
Tel
21-31433387 15618786686
Fax
QQ:1369748377
Email
sales@rechemscience.com
Country
China
ProdList
2982
Advantage
58
Chengdu MassCale Pharmaceutical Co., Ltd.
Tel
028-84552636 18084815636
Email
chensfsc@126.com
Country
China
ProdList
1445
Advantage
58
Jiangsu aikang biomedical research and development co., LTD
Tel
025-66110311 13155353615
Email
qzhang@aikonchem.com
Country
China
ProdList
15527
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32038
Advantage
58
PCL - Business, Laboratory Pharmaceutical
Tel
19150123681
Fax
QQ:3008022628
Email
Hu.xinyue@purechemland.com
Country
China
ProdList
3566
Advantage
58

115687-05-3, CPNQRelated Search:

Oseltamivir phosphate 1-[4-(4-AMINO-PHENYL)-PIPERAZIN-1-YL]-ETHANONE CPNQ 4-(4-BENZYLPIPERAZINO)ANILINE 1-BENZYL-4-(4-NITROPHENYL)PIPERAZINE (4-CHLOROPHENYL)(PIPERAZIN-1-YL) METHANONE 1-Acetyl-4-(4-nitrophenyl)piperazine 1-(4-Nitrophenyl)piperazine

  • 5-[4-(4-Chlorobenzoyl)-1-piperazinyl]-8-nitroquinoline
  • B2
  • Linazolamide intermediate B impurity 2
  • (4-chlorophenyl)-[4-(8-nitroquinolin-5-yl)piperazin-1-yl]methanone
  • SIRT2 Inhibitor, B2
  • Methanone, (4-chlorophenyl)[4-(8-nitro-5-quinolinyl)-1-piperazinyl]-
  • Sirtuin,Parkinson’s diseases,Huntington’s diseases,Inhibitor,B2,inhibit,B-2
  • SIRT2-IN-8
  • CPNQ
  • 115687-05-3