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RUBRATOXINA

Product Name
RUBRATOXINA
CAS No.
22467-31-8
Chemical Name
RUBRATOXINA
Synonyms
RUBRATOXINA;Rubratoxin A, PP2A inhibitor;10-[(3,6-Dihydro-6-oxo-2H-pyran-2-yl)hydroxymethyl]-4,5,8,9,10,11-hexahydro-4,8-dihydroxy-5-(1-hydroxyheptyl)-1H-cyclonona[1,2-c:5,6-c']difuran-1,3,6-trione;9-[(3,6-Dihydro-6-oxo-2H-pyran-2-yl)hydroxymethyl]-3,4,5,8,9,10-hexahydro-1,5-dihydroxy-4-(1-hydroxyheptyl)-3-oxo-1H-cyclonona[c]furan-6,7-dicarboxylic anhydride;1H-Cyclonona[1,2-c:5,6-c']difuran-1,3,6-trione, 10-[(R)-[(2R)-3,6-dihydro-6-oxo-2H-pyran-2-yl]hydroxymethyl]-4,5,8,9,10,11-hexahydro-4,8-dihydroxy-5-[(1S)-1-hydroxyheptyl]-, (4S,5R,10R)-rel-
CBNumber
CB81405198
Molecular Formula
C26H32O11
Formula Weight
520.528
MOL File
22467-31-8.mol
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RUBRATOXINA Property

Melting point:
210-214℃ (decomposition)
storage temp. 
Store at -20°C
solubility 
Acetonitrile: soluble; DMSO: soluble
form 
A powder
color 
White
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Safety

Hazardous Substances Data
22467-31-8(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
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N-Bromosuccinimide Price

Cayman Chemical
Product number
19605
Product name
Rubratoxin A
Purity
≥95%
Packaging
250μg
Price
$299
Updated
2024/03/01
Cayman Chemical
Product number
19605
Product name
Rubratoxin A
Purity
≥95%
Packaging
500μg
Price
$507
Updated
2024/03/01
TRC
Product number
R701543
Product name
RubratoxinA
Packaging
100μg
Price
$365
Updated
2021/12/16
Usbiological
Product number
207390
Product name
Rubratoxin A
Packaging
250ug
Price
$460
Updated
2021/12/16
Adipogen Life Sciences
Product number
AG-CN2-0092-C500
Product name
RubratoxinA
Purity
≥95%(HPLC)
Packaging
500μg
Price
$540
Updated
2021/12/16
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RUBRATOXINA Chemical Properties,Usage,Production

Description

Rubratoxin A is a natural mycotoxin and competitive inhibitor of protein phosphatase 2A (PP2A; IC50 = 170 nM). It has no significant effect on several other phosphatases, including PP1, PP2B, and protein tyrosine phosphatase 1B. Rubratoxin A drives overphosphorylation of PP2A substrate proteins in cultured cells treated for three hours at 20 μM. It causes suppression of tumor metastasis and reduction of primary tumor volume in mouse xenografts.

Uses

Rubratoxin A is a potent and selective competitive PP2A inhibitor.

storage

-20°C

RUBRATOXINA Preparation Products And Raw materials

Raw materials

Preparation Products

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RUBRATOXINA Suppliers

China 10 United Kingdom 1 United States 7 Global 18
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
52924
Advantage
58
United States Biological
Tel
--
Fax
--
Email
sales@advtechind.com
Country
United States
ProdList
6075
Advantage
58
Abcam
Tel
--
Fax
--
Email
us.orders@abcam.com
Country
United States
ProdList
6001
Advantage
50
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
Santa Cruz Biotechnology, Inc.
Tel
--
Fax
--
Email
scbt@scbt.com
Country
United States
ProdList
3597
Advantage
60

22467-31-8, RUBRATOXINARelated Search:

RUBRATOXINA 2,3-Dimethylmaleic anhydride DIMETHYL DECADIENAL 4-METHYLPENTANOIC ANHYDRIDE 2,4-DIMETHYL-2,6-HEPTADIEN-1-OL (+/-)-LAVANDULOL 2,5-DIMETHYL-1,5-HEXADIEN-3-OL 5-HYDROXY-4-METHYL-2(5H)FURANONE 2-Isopropyl-5-methyl-2-hexenal (CIS)-8-METHYLNON-6-ENOIC ACID GERANIC ACID

  • RUBRATOXINA
  • 10-[(3,6-Dihydro-6-oxo-2H-pyran-2-yl)hydroxymethyl]-4,5,8,9,10,11-hexahydro-4,8-dihydroxy-5-(1-hydroxyheptyl)-1H-cyclonona[1,2-c:5,6-c']difuran-1,3,6-trione
  • 9-[(3,6-Dihydro-6-oxo-2H-pyran-2-yl)hydroxymethyl]-3,4,5,8,9,10-hexahydro-1,5-dihydroxy-4-(1-hydroxyheptyl)-3-oxo-1H-cyclonona[c]furan-6,7-dicarboxylic anhydride
  • 1H-Cyclonona[1,2-c:5,6-c']difuran-1,3,6-trione, 10-[(R)-[(2R)-3,6-dihydro-6-oxo-2H-pyran-2-yl]hydroxymethyl]-4,5,8,9,10,11-hexahydro-4,8-dihydroxy-5-[(1S)-1-hydroxyheptyl]-, (4S,5R,10R)-rel-
  • Rubratoxin A, PP2A inhibitor
  • 22467-31-8