2,4-DIAMINO-PYRIMIDINE-5-CARBALDEHYDE
- Product Name
- 2,4-DIAMINO-PYRIMIDINE-5-CARBALDEHYDE
- CAS No.
- 20781-06-0
- Chemical Name
- 2,4-DIAMINO-PYRIMIDINE-5-CARBALDEHYDE
- Synonyms
- NSC 211353;AURORA KA-6757;2,4-Diamino-5-formylpyrimidine;2,4-DIAMINO-PYRIMIDINE-5-CARBALDEHYDE;2,6-DiaMino-5-pyriMidinecarboxaldehyde;2,4-DiaMino-5-pyriMidinecarboxaldehyde;2,4-DIAMINOPYRIMIDINE-5-CARBOXALDEHYDE;5-Pyrimidinecarboxaldehyde, 2,4-diamino-;5-Pyrimidinecarboxaldehyde, 2,4-diamino- (6CI,8CI,9CI);2,4-DIAMINO-PYRIMIDINE-5-CARBALDEHYDE ISO 9001：2015 REACH
- CBNumber
- CB8143503
- Molecular Formula
- C5H6N4O
- Formula Weight
- 138.13
- MOL File
- 20781-06-0.mol
2,4-DIAMINO-PYRIMIDINE-5-CARBALDEHYDE Property
- Melting point:
- 274-276°C
- Boiling point:
- 468.3±55.0 °C(Predicted)
- Density
- 1.499±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- solubility
- DMSO, Methanol
- form
- Solid
- pka
- 5.32±0.10(Predicted)
- color
- Yellow
- CAS DataBase Reference
- 20781-06-0(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 36/37/38-43-36-22
- Safety Statements
- 26-36/37/39-36/37
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H317May cause an allergic skin reaction
H319Causes serious eye irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D416750
- Product name
- 2,4-Diaminopyrimidine-5-carboxaldehyde
- Packaging
- 100mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- D416750
- Product name
- 2,4-Diaminopyrimidine-5-carboxaldehyde
- Packaging
- 1g
- Price
- $230
- Updated
- 2021/12/16
- Product number
- FD11505
- Product name
- 2,4-Diaminopyrimidine-5-carboxaldehyde
- Packaging
- 100mg
- Price
- $69
- Updated
- 2021/12/16
- Product number
- FD11505
- Product name
- 2,4-Diaminopyrimidine-5-carboxaldehyde
- Packaging
- 250mg
- Price
- $100
- Updated
- 2021/12/16
- Product number
- FD11505
- Product name
- 2,4-Diaminopyrimidine-5-carboxaldehyde
- Packaging
- 500mg
- Price
- $160
- Updated
- 2021/12/16
2,4-DIAMINO-PYRIMIDINE-5-CARBALDEHYDE Chemical Properties,Usage,Production
Chemical Properties
Yellow Solid
Uses
Intermediate for the preparation of medicines and agrochemicals.
Synthesis
64-18-6
16462-27-4
20781-06-0
The general procedure for the synthesis of 2,4-diaminopyrimidine-5-carboxaldehyde from formic acid and 2,4-diaminopyrimidine-5-carbonitrile is as follows: nickel ruanne (2.5 g, 50% aqueous slurry) was added to a 98-100% solution of formic acid (20 mL) containing 2,4-diaminopyrimidine-5-carbonitrile (2.0 g, 14.8 mmol). The reaction mixture was refluxed for 3-4 hours. Upon completion of the reaction, the reaction mixture was filtered and the solid was washed with formic acid (10 mL). The filtrate and washings were combined and concentrated under reduced pressure. The concentrated residue was stirred in 30% aqueous ammonia solution and subsequently cooled to give a free flowing solid product. The product was collected by filtration, washed with water and dried to give 2,4-diaminopyrimidine-5-carbaldehyde (1.8 g, 78% yield) as an off-white solid.
References
[1] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 7, p. 2428 - 2433
2,4-DIAMINO-PYRIMIDINE-5-CARBALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2,4-DIAMINO-PYRIMIDINE-5-CARBALDEHYDE manufacturers
- Product
- 2,4-DIAMINO-PYRIMIDINE-5-CARBALDEHYDE 20781-06-0
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-12-10
- Product
- 2,4-DIAMINO-PYRIMIDINE-5-CARBALDEHYDE 20781-06-0
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200KG
- Release date
- 2020-03-23