Pyrimidine-5-carboxaldehyde

Product Name: Pyrimidine-5-carboxaldehyde
CAS No.: 10070-92-5
Chemical Name: Pyrimidine-5-carboxaldehyde
Synonyms: PYRIMIDINE-5-CARBALDEHYDE;5-PYRIMIDINECARBOXALDEHYDE;5-FORMYLPYRIMIDINE;RARECHEM AK ML 0565;PyriMidin-5-carbaldehyde;5-Pyrimidinecarbaldehyde;Pyrimidine-5-formaldehyde;PYRIMIDINE-5-CARBOXALDEHYDE;PYRIMIDINE-5-CARBOXYALDEHYDE;Pyrimidine-5-carboxylaldehyde
CBNumber: CB8412180
Molecular Formula: C5H4N2O
Formula Weight: 108.1
MOL File: 10070-92-5.mol

More

Less

Pyrimidine-5-carboxaldehyde Property

Melting point:: 39-43°C
Boiling point:: 80-82°C 4mm
Density: 1.23
storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
pka: 1.15±0.10(Predicted)
form: solid
color: Light yellow to yellow
InChI: InChI=1S/C5H4N2O/c8-3-5-1-6-4-7-2-5/h1-4H
InChIKey: FREJAOSUHFGDBW-UHFFFAOYSA-N
SMILES: C1=NC=C(C=O)C=N1
CAS DataBase Reference: 10070-92-5(CAS DataBase Reference)

More

Less

Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-43-22
Safety Statements: 26-36/37/39-36-36/37
WGK Germany: WGK 3
HazardClass: IRRITANT
HS Code: 2933599590
Storage Class: 11 - Combustible Solids
Hazard Classifications: Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
Skin Sens. 1
STOT SE 3

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: CDS004733
Product name: pyrimidine-5-carboxaldehyde
Purity: Aldrich<SUP>CPR</SUP>
Packaging: 100 mg
Price: $87.5
Updated: 2025/07/31

TRC

Product number: P997265
Product name: 5-Pyrimidinecarboxaldehyde
Packaging: 5g
Price: $925
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: P1680
Product name: 5-Formylpyrimidine
Purity: >97%
Packaging: 25g
Price: $373
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0032010
Product name: PYRIMIDINE-5-CARBOXALDEHYDE
Purity: 95.00%
Packaging: 100MG
Price: $739.2
Updated: 2021/12/16

AK Scientific

Product number: G603
Product name: Pyrimidine-5-carbaldehyde
Packaging: 100g
Price: $1154
Updated: 2021/12/16

More

Less

Pyrimidine-5-carboxaldehyde Chemical Properties,Usage,Production

Uses

Pyrimidine-5-carboxaldehyde is used in the preparation of (S)- and (R)-pyrimidyl alkanol by reacting with diisopropylzinc and (n-butyl)ethyl(n-hexyl)(n-propyl)methane.

Synthesis

Under nitrogen, a solution of 5-bromopyrimidine (1 g, 6.3 mmol) in 60 mL anhydrous THF was added BuLi (2.5 M, 2.6 mL, 6.5 mmol) at -78° C. The resulting yellow solution was stirred for 20 min, after which ethyl formate (0.55 mL, 6.7 mmol) was added dropwise over 5 min. After 20 min, the reaction was quenched with 1.5 M THF/HCl solution (4.5 mL, 6.7 mmol). The cold bath was removed, and the reaction mixture was stirred for 1 h. THF was removed in vacco, 10 mL of water was then added. The mixture was extracted with CHCl3 (2*10 mL), and the combined organics were dried (MgSO4) and concentrated. The crude product was purified via flash column chromatography (5 per cent MeOH/CHCl3) to give 0.35 g (51 per cent) of the titled Pyrimidine-5-carboxaldehyde.

References

[1] Journal of medicinal chemistry, 2004, vol. 47, # 20, p. 4829 - 4837
[2] Patent: US2005/70712, 2005, A1. Location in patent: Page/Page column 42
[3] Patent: US2005/171131, 2005, A1. Location in patent: Page/Page column 41
[4] Patent: US9212138, 2015, B2. Location in patent: Page/Page column 42
[5] ChemMedChem, 2017, vol. 12, # 3, p. 257 - 270

Pyrimidine-5-carboxaldehyde Preparation Products And Raw materials

Raw materials

Nitrogen Ethyl formate Tetrahydrofuran Diethyl ether Ethyl acetate Hydrochloric acid 5-Bromopyrimidine Magnesium sulfate PETROLEUM ETHER n-Butyllithium

Preparation Products

More

Less

Pyrimidine-5-carboxaldehyde Suppliers

Belgium 1 Canada 4 China 230 Europe 1 France 1 Germany 7 India 10 Poland 1 Switzerland 1 The Netherlands 1 United Kingdom 12 United States 46 Global 315

Shanghai Changer Pharmaceutical Technology Co. Ltd.

Tel: 15921595598
Email: qd.yu@pharmachanger.com
Country: China
ProdList: 468
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Shanghai Sinch Parmaceuticals Tech. Co. Ltd.

Tel: +86-21-54098501
Fax: +86-21-54096319
Email: sales@sinch.com.cn
Country: China
ProdList: 11598
Advantage: 64

Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd.

Tel: 21-57721279 18121011378
Fax: QQ：14057904
Email: sales@shydchem.com.cn
Country: China
ProdList: 998
Advantage: 56

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9892
Advantage: 59

More

Less

View Lastest Price from Pyrimidine-5-carboxaldehyde manufacturers

PUSHAN INDUSTRIAL (SHAANXI) CO.,LTD

Product: Pyrimidine-5-carboxaldehyde 10070-92-5
Price: US $0.00/kg
Min. Order: 1kg
Purity: 95%
Supply Ability: 5-10 MTs
Release date: 2024-05-10

Dideu Industries Group Limited

Product: Pyrimidine-5-carboxaldehyde 10070-92-5
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons
Release date: 2022-02-09

Zhuozhou Wenxi import and Export Co., Ltd

Product: Pyrimidine-5-carbaldehyde 10070-92-5
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

10070-92-5, Pyrimidine-5-carboxaldehydeRelated Search:

Formaldehyde Sulfadiazine Fluorocytosine Pyrimidine Uracil Silver sulfadiazine 5-METHYLCYTOSINE PYRIMIDINE-4-CARBOXALDEHYDE Pyrimidine-5-boronic acid pinacol ester 2-Pyrimidinecarboxamide (6CI,7CI,9CI) Pyrimidine-2-carboxylic acid 5-Pyrimidinecarboxylic acid Pyrrole-2-carboxaldehyde PYRROLE-2-CARBONITRILE Pyrrole-2-carboxylic acid 5-PYRIMIDINECARBOXAMIDE PYRIMIDINE-4-CARBOXYLIC ACID METHYL ESTER 4,6-PYRIMIDINE DICARBOXYLIC ACID

5-FORMYLPYRIMIDINE

RARECHEM AK ML 0565

PYRIMIDINE-5-CARBOXYALDEHYDE

PYRIMIDINE-5-CARBALDEHYDE

PYRIMIDINE-5-CARBOXALDEHYDE

5-PYRIMIDINECARBOXALDEHYDE

5-Pyrimidinecarboxaldehyde (7CI,8CI,9CI)

5-Pyrimidinecarbaldehyde

Pyrimidine-5-carboxylaldehyde

PyriMidin-5-carbaldehyde

5-Formylpyrimidine, 5-Formyl-1,3-diazine

PyriMidine-5-carbaldehyde 5-ForMylpyriMidine

Pyrimidine-5-carboxaldehyde ISO 9001：2015 REACH

Pyrimidine-5-formaldehyde

10070-92-5

Heterocycle-Pyrimidine series

Aromatics

Heterocycles

PYRIMIDINE

Aldehyde

Building Blocks

Pyrimidines

Boronic Acid

Heterocyclic Compounds