PYRIMIDINE-4-CARBOXALDEHYDE
Uses- Product Name
- PYRIMIDINE-4-CARBOXALDEHYDE
- CAS No.
- 2435-50-9
- Chemical Name
- PYRIMIDINE-4-CARBOXALDEHYDE
- Synonyms
- 4-Pyrimidinecarboxaldehyde;RARECHEM AK ML 0567;4-PYRIMIDINE CARBALDEHYDE;PYRIMIDINE-4-CARBOXALDEHYDE;4-Formylpyrimidine, 4-Formyl-1,3-diazine;4-Pyrimidinecarboxaldehyde (7CI,8CI,9CI);PYRIMIDINE-4-CARBOXALDEHYDE ISO 9001：2015 REACH
- CBNumber
- CB6382911
- Molecular Formula
- C5H4N2O
- Formula Weight
- 108.1
- MOL File
- 2435-50-9.mol
PYRIMIDINE-4-CARBOXALDEHYDE Property
- Boiling point:
- 225.3±13.0 °C(Predicted)
- Density
- 1.234±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- pka
- -0.14±0.10(Predicted)
- form
- liquid
- color
- Clear, faint yellow
- InChI
- InChI=1S/C5H4N2O/c8-3-5-1-2-6-4-7-5/h1-4H
- InChIKey
- OKULHRWWYCFJAB-UHFFFAOYSA-N
- SMILES
- C1=NC=CC(C=O)=N1
Safety
- RIDADR
- 1993
- HazardClass
- 3
- PackingGroup
- Ⅲ
- HS Code
- 2933599590
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
N-Bromosuccinimide Price
- Product number
- 4H15-1-Z1
- Product name
- Pyrimidine-4-carboxaldehyde
- Packaging
- 250mg
- Price
- $85
- Updated
- 2021/12/16
- Product number
- 072216
- Product name
- Pyrimidine-4-carbaldehyde
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $138
- Updated
- 2021/12/16
- Product number
- 4H15-1-Z1
- Product name
- Pyrimidine-4-carboxaldehyde
- Packaging
- 1g
- Price
- $253
- Updated
- 2021/12/16
- Product number
- 072216
- Product name
- Pyrimidine-4-carbaldehyde
- Purity
- 95+%
- Packaging
- 1g
- Price
- $347
- Updated
- 2021/12/16
- Product number
- CHM0975051
- Product name
- PYRIMIDINE-4-CARBOXALDEHYDE
- Purity
- 95.00%
- Packaging
- 250MG
- Price
- $791.18
- Updated
- 2021/12/16
PYRIMIDINE-4-CARBOXALDEHYDE Chemical Properties,Usage,Production
Uses
Pyrimidine-4-carboxaldehyde is an aldehyde derivative that can be used as a pharmaceutical intermediate.
Synthesis
3438-46-8
2435-50-9
Method G: Synthesis of the intermediate 7(1-7) - pyrimidine-4-carbaldehyde. To a 10 mL solution of dioxane containing 1.0 g (10 mmol, 1.0 eq.) of 4-methylpyrimidine was added 1.2 g (10 mmol, 1.0 eq.) of selenium dioxide. The reaction mixture was heated at 100 °C for 5 hours and subsequently cooled to room temperature. After the addition of 0.25 g (2.3 mmol, 0.23 eq.) of selenium dioxide was made up, the heating was continued at 100 °C for 1 hour. After completion of the reaction, the mixture was cooled to room temperature and filtered through Celite. The filter cake was washed with 200 mL of ethyl acetate, and the filtrates were combined and concentrated under vacuum. The resulting dark brown oil was suspended with 200 mL of dichloromethane and filtered. Finally, the solvent was removed by vacuum to give 0.3 g (2.8 mmol, 28% yield) of pyrimidine-4-carbaldehyde (1-7) as a dark brown oily product.
References
[1] Heterocycles, 2003, vol. 60, # 4, p. 953 - 957
[2] Patent: WO2007/104053, 2007, A2. Location in patent: Page/Page column 36
[3] Patent: US2003/125339, 2003, A1
[4] Patent: EP150984, 1991, B1
[5] Patent: US4826833, 1989, A
PYRIMIDINE-4-CARBOXALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
PYRIMIDINE-4-CARBOXALDEHYDE Suppliers
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View Lastest Price from PYRIMIDINE-4-CARBOXALDEHYDE manufacturers
- Product
- PYRIMIDINE-4-CARBOXALDEHYDE 2435-50-9
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons
- Release date
- 2022-02-09
- Product
- pyriMidine-4-carboxaldehyde 2435-50-9
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27
- Product
- PYRIMIDINE-4-CARBOXALDEHYDE 2435-50-9
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 200kg
- Release date
- 2018-12-24