5-AMINOMETHYL INDAZOLE

Product Name: 5-AMINOMETHYL INDAZOLE
CAS No.: 267413-25-2
Chemical Name: 5-AMINOMETHYL INDAZOLE
Synonyms: (1H-Indazol-5-yl);5-Indazolylmethanamine;5-AMINOMETHYL INDAZOLE;5-Aminomethyl-1H-indazole;1H-Indazole-5-methanamine;(1H-indazol-5-yl)methanamine;1-(1H-indazol-5-yl)methanamine;C-(1H-Indazol-5-yl)-methylamine
CBNumber: CB81494057
Molecular Formula: C8H9N3
Formula Weight: 147.18
MOL File: 267413-25-2.mol

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5-AMINOMETHYL INDAZOLE Property

Boiling point:: 352.1±17.0 °C(Predicted)
Density: 1.278±0.06 g/cm3(Predicted)
storage temp.: 2-8°C, protect from light
form: solid
pka: 14.10±0.40(Predicted)
color: Tan

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: I509013
Product name: (1H-Indazol-5-yl)methanamine
Packaging: 25mg
Price: $45
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: A11389
Product name: 5-(Aminomethyl)-1H-indazole
Purity: 95%
Packaging: 500mg
Price: $235
Updated: 2021/12/16

AK Scientific

Product number: W4997
Product name: (1H-Indazol-5-yl)methanamine
Packaging: 250mg
Price: $107
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H30-1-H9
Product name: 5-(Aminomethyl)-1H-indazole
Packaging: 250mg
Price: $109
Updated: 2021/12/16

Matrix Scientific

Product number: 070493
Product name: 5-(Aminomethyl)-1H-indazole
Purity: 97%
Packaging: 1g
Price: $530
Updated: 2021/12/16

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5-AMINOMETHYL INDAZOLE Chemical Properties,Usage,Production

Synthesis

74626-47-4

267413-25-2

The general procedure for the synthesis of 5-aminomethylindazole from 1H-indazole-5-carbonitrile was as follows: 1H-indazole-5-carbonitrile (100 mg, 0.699 mmol) was dissolved in tetrahydrofuran (4 mL) at room temperature, and this solution was subsequently added slowly to a suspension of lithium aluminum hydride (53 mg, 1.40 mmol) in tetrahydrofuran (4 mL). The reaction mixture was heated to reflux for 2 hours. Upon completion of the reaction, water (0.053 mL), 2 N aqueous lithium hydroxide (0.106 mL) and water (0.212 mL) were sequentially added to the reaction system, stirred and filtered. The filtrate was concentrated under reduced pressure to remove the solvent and the residue was dried under reduced pressure to afford the target product 1-(1H-indazol-5-yl)methylamine (97 mg, 94% yield).

References

[1] Patent: EP1403255, 2004, A1. Location in patent: Page 56
[2] Patent: US6376499, 2002, B1
[3] Bioorganic and Medicinal Chemistry Letters, 2009, vol. 19, # 15, p. 4191 - 4195
[4] Patent: WO2010/47990, 2010, A1. Location in patent: Page/Page column 18; 33
[5] Patent: WO2010/82044, 2010, A1. Location in patent: Page/Page column 34

5-AMINOMETHYL INDAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-AMINOMETHYL INDAZOLE Suppliers

China 73 Germany 1 India 1 United Kingdom 1 United States 14 Global 90

J & K SCIENTIFIC LTD.

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View Lastest Price from 5-AMINOMETHYL INDAZOLE manufacturers

Career Henan Chemical Co

Product: 5-AMINOMETHYL INDAZOLE 267413-25-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2020-01-09

267413-25-2, 5-AMINOMETHYL INDAZOLERelated Search:

5-AMINOMETHYL INDAZOLE 1-METHYL-3-PROPYL-4-NITRO-INDAZOLE-5-CARBOXAMIDE 3-AMINO-5-AMINOMETHYL-1H-INDAZOLE HYDROCHLORIDE

5-AMINOMETHYL INDAZOLE

5-Aminomethyl-1H-indazole

C-(1H-Indazol-5-yl)-methylamine

(1H-Indazol-5-yl)

(1H-indazol-5-yl)methanamine

1H-Indazole-5-methanamine

1-(1H-indazol-5-yl)methanamine

5-Indazolylmethanamine

267413-25-2

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