5-AMINOMETHYL INDAZOLE
- Product Name
- 5-AMINOMETHYL INDAZOLE
- CAS No.
- 267413-25-2
- Chemical Name
- 5-AMINOMETHYL INDAZOLE
- Synonyms
- (1H-Indazol-5-yl);5-Indazolylmethanamine;5-AMINOMETHYL INDAZOLE;5-Aminomethyl-1H-indazole;1H-Indazole-5-methanamine;(1H-indazol-5-yl)methanamine;1-(1H-indazol-5-yl)methanamine;C-(1H-Indazol-5-yl)-methylamine
- CBNumber
- CB81494057
- Molecular Formula
- C8H9N3
- Formula Weight
- 147.18
- MOL File
- 267413-25-2.mol
5-AMINOMETHYL INDAZOLE Property
- Boiling point:
- 352.1±17.0 °C(Predicted)
- Density
- 1.278±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C, protect from light
- form
- solid
- pka
- 14.10±0.40(Predicted)
- color
- Tan
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- I509013
- Product name
- (1H-Indazol-5-yl)methanamine
- Packaging
- 25mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- W4997
- Product name
- (1H-Indazol-5-yl)methanamine
- Packaging
- 250mg
- Price
- $107
- Updated
- 2021/12/16
- Product number
- 3H30-1-H9
- Product name
- 5-(Aminomethyl)-1H-indazole
- Packaging
- 250mg
- Price
- $109
- Updated
- 2021/12/16
- Product number
- A11389
- Product name
- 5-(Aminomethyl)-1H-indazole
- Purity
- 95%
- Packaging
- 500mg
- Price
- $235
- Updated
- 2021/12/16
- Product number
- A11389
- Product name
- 5-(Aminomethyl)-1H-indazole
- Purity
- 95%
- Packaging
- 1g
- Price
- $350
- Updated
- 2021/12/16
5-AMINOMETHYL INDAZOLE Chemical Properties,Usage,Production
Synthesis
74626-47-4
267413-25-2
The general procedure for the synthesis of 5-aminomethylindazole from 1H-indazole-5-carbonitrile was as follows: 1H-indazole-5-carbonitrile (100 mg, 0.699 mmol) was dissolved in tetrahydrofuran (4 mL) at room temperature, and this solution was subsequently added slowly to a suspension of lithium aluminum hydride (53 mg, 1.40 mmol) in tetrahydrofuran (4 mL). The reaction mixture was heated to reflux for 2 hours. Upon completion of the reaction, water (0.053 mL), 2 N aqueous lithium hydroxide (0.106 mL) and water (0.212 mL) were sequentially added to the reaction system, stirred and filtered. The filtrate was concentrated under reduced pressure to remove the solvent and the residue was dried under reduced pressure to afford the target product 1-(1H-indazol-5-yl)methylamine (97 mg, 94% yield).
References
[1] Patent: EP1403255, 2004, A1. Location in patent: Page 56
[2] Patent: US6376499, 2002, B1
[3] Bioorganic and Medicinal Chemistry Letters, 2009, vol. 19, # 15, p. 4191 - 4195
[4] Patent: WO2010/47990, 2010, A1. Location in patent: Page/Page column 18; 33
[5] Patent: WO2010/82044, 2010, A1. Location in patent: Page/Page column 34
5-AMINOMETHYL INDAZOLE Preparation Products And Raw materials
Raw materials
Preparation Products
5-AMINOMETHYL INDAZOLE Suppliers
- Tel
- --
- Fax
- --
- info@abcr.de
- Country
- Germany
- ProdList
- 6831
- Advantage
- 75
View Lastest Price from 5-AMINOMETHYL INDAZOLE manufacturers
- Product
- 5-AMINOMETHYL INDAZOLE 267413-25-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-01-09