ChemicalBook > CAS DataBase List > 2-HYDROXY-3''-NITRO-BIPHENYL-3-CARBOXYLIC ACID

2-HYDROXY-3''-NITRO-BIPHENYL-3-CARBOXYLIC ACID

Product Name
2-HYDROXY-3''-NITRO-BIPHENYL-3-CARBOXYLIC ACID
CAS No.
376591-95-6
Chemical Name
2-HYDROXY-3''-NITRO-BIPHENYL-3-CARBOXYLIC ACID
Synonyms
Eltrombopag o;4,5,9,16-Pyrenetetrone;Nalbuphine Impurity 11;Eltrombopag Impurity 21;Eltrombopag Impurity 44;Eltrombopag Impurity 13;Eltrombopag olamine Intermediate 2;3-(2-hydroxy-3-nitrophenyl)benzoicaci;3-(2-hydroxy-3-nitrophenyl)benzoic acid;2'-hydroxy-3'-nitro-3-biphenylcarboxylic acid
CBNumber
CB81501917
Molecular Formula
C13H9NO5
Formula Weight
259.21
MOL File
376591-95-6.mol
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2-HYDROXY-3''-NITRO-BIPHENYL-3-CARBOXYLIC ACID Property

Boiling point:
452.2±40.0 °C(Predicted)
Density 
1.460±0.06 g/cm3(Predicted)
storage temp. 
Room Temperature
solubility 
Tetrahydrofuran; Methanol;
form 
Solid
pka
3.96±0.10(Predicted)
color 
Yellow
InChI
InChI=1S/C13H9NO5/c15-12-10(5-2-6-11(12)14(18)19)8-3-1-4-9(7-8)13(16)17/h1-7,15H,(H,16,17)
InChIKey
JCFPSTQCDAZKJN-UHFFFAOYSA-N
SMILES
C1(C2=CC=CC([N+]([O-])=O)=C2O)=CC=CC(C(O)=O)=C1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TRC
Product number
N527820
Product name
3’-Nitro-2’-hydroxy[1,1’]-biphenyl-3-carboxylicAcid
Packaging
50mg
Price
$180
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0381774
Product name
2-HYDROXY-3'-NITRO-BIPHENYL-3-CARBOXYLIC ACID
Purity
95.00%
Packaging
5MG
Price
$504.48
Updated
2021/12/16
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2-HYDROXY-3''-NITRO-BIPHENYL-3-CARBOXYLIC ACID Chemical Properties,Usage,Production

Uses

3’-Nitro-2’-hydroxy[1,1’]-biphenyl-3-carboxylic Acid is an intermediate used in the synthesis of N-Hydroxy Eltrombopag (H825795), which is a derivative compound of Eltrombopag (508000), an agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia.

2-HYDROXY-3''-NITRO-BIPHENYL-3-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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2-HYDROXY-3''-NITRO-BIPHENYL-3-CARBOXYLIC ACID Suppliers

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View Lastest Price from 2-HYDROXY-3''-NITRO-BIPHENYL-3-CARBOXYLIC ACID manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
2-Hydroxy-3''-Nitro-Biphenyl-3-Carboxylic Acid 376591-95-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-30
Shanghai Joiny Pharmaceutical Co.,LTD
Product
2'-Hydroxy-3'-nitro-[1,1'-biphenyl]-3-carboxylic acid 376591-95-6
Price
US $0.00/kg
Min. Order
1kg
Purity
98%~102%
Supply Ability
1000kg
Release date
2024-01-16
ShenZhen H&D Pharmaceutical Technology Co., LTD
Product
Eltrombopag Impurity 44
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
0.98
Supply Ability
10g
Release date
2024-04-16

376591-95-6, 2-HYDROXY-3''-NITRO-BIPHENYL-3-CARBOXYLIC ACIDRelated Search:

4-Nitrobiphenyl Benzoic acid Sodium iodide Poly(vinyl alcohol) Monoethanolamine Dimethyl phthalate L-Arabinopyranose Trimethylolpropane 2-N-BUTOXYETHYL METHACRYLATE Potassium pyrophosphate 3H-Pyrazol-3-one, 1-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl- 2-Bromo-6-nitrophenol Eltrombopag Impurity 49 Pyromellitic Dianhydride Biphenyl-4,4'-dicarboxylic acid 4-Chlorophthalic anhydride 1,2,3,4-Butanetetracarboxylic acid 1,2,3,4-Cyclobutanetetracarboxylic Dianhydride

  • 2'-hydroxy-3'-nitro-3-biphenylcarboxylic acid
  • 2'-Hydroxy-3'-nitro-[1,1'-biphenyl]-3-carboxylic acid
  • 2-HYDROXY-3''-NITRO-BIPHENYL-3-CARBOXYLIC ACID
  • Eltrombopag o
  • 3-(2-hydroxy-3-nitrophenyl)benzoic acid
  • Eltrombopag olamine Intermediate 2
  • 3’-Nitro-2’-hydroxy[1,1’]-biphenyl-3-carboxylic Acid
  • Eltrombopag Impurity 13
  • [1,1'-Biphenyl]-3-carboxylic acid, 2'-hydroxy-3'-nitro-
  • Eltrombopag Impurity 44
  • Eltrombopag Impurity 21
  • 4,5,9,16-Pyrenetetrone
  • 3-(2-hydroxy-3-nitrophenyl)benzoicaci
  • 2'- hydroxy -3'- nitrobiphenyl -3- carboxylic acid
  • 2'-hydroxy-3'-nitro-3- biphenylcarboxylic acid
  • Nalbuphine Impurity 11
  • 376591-95-6