ChemicalBook > CAS DataBase List > Ac-Arg-Leu-Arg-AMC
Ac-Arg-Leu-Arg-AMC
- Product Name
- Ac-Arg-Leu-Arg-AMC
- CAS No.
- 929903-87-7
- Chemical Name
- Ac-Arg-Leu-Arg-AMC
- Synonyms
- Ac-RLR-AMC;Ac-Arg-Leu-Arg-AMC;Ac-Arg-Leu-Arg-AMC trifluoroacetate salt;N2-Acetyl-L-arginyl-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-argininamide;L-Argininamide,N2-acetyl-L-arginyl-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
- CBNumber
- CB81513176
- Molecular Formula
- C30H46N10O6
- Formula Weight
- 642.75
- MOL File
- 929903-87-7.mol
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Ac-Arg-Leu-Arg-AMC Property
- Density
- 1.39±0.1 g/cm3(Predicted)
- pka
- 13.29±0.46(Predicted)
- color
- Solid lyophilized powder
- Sequence
- Ac-Arg-Leu-Arg-AMC
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N-Bromosuccinimide Price
Usbiological
- Product number
- 226820
- Product name
- Ac-Arg-Leu-Arg-AMC
- Packaging
- 1mg
- Price
- $295
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- PEP0020997
- Product name
- AC-ARG-LEU-ARG-AMC
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $530
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FA110603
- Product name
- Ac-Arg-Leu-Arg-AMC trifluoroacetate salt
- Packaging
- 5mg
- Price
- $570
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FA110603
- Product name
- Ac-Arg-Leu-Arg-AMC trifluoroacetate salt
- Packaging
- 10mg
- Price
- $991.3
- Updated
- 2021/12/16
Adipogen Life Sciences
- Product number
- AG-CP3-0013-M001
- Product name
- Ac-Arg-Leu-Arg-AMC
- Purity
- ≥97%(HPLC)
- Packaging
- 1mg
- Price
- $55
- Updated
- 2021/12/16
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Ac-Arg-Leu-Arg-AMC Chemical Properties,Usage,Production
Uses
Ac-RLR-AMC (Ac-Arg-Leu-Arg-AMC) is a fluorogenic substrate for the 26S proteasome (Ex/Em: 380/440-460 nm). AMC is released upon cleavage, and its fluorescence can be used to quantify the trypsin-like activity of 26S proteasomes[1].
Biological Activity
Fluorogenic tri-peptide substrate for measuring the trypsin-like peptidase activity of the 20S proteasome. It is cleaved exclusively at the amide R-AMC bond to release fluorescent product. Shows low Km and high specific activity. Excitation: 380nm. Emission: 460nm. This substrate is useful for inhibitor screening and kinetic analysis.
storage
+4°C
References
[1] Chang TL. Inhibitory effect of flavonoids on 26S proteasome activity. J Agric Food Chem. 2009 Oct 28;57(20):9706-15. DOI:10.1021/jf9017492
Ac-Arg-Leu-Arg-AMC Preparation Products And Raw materials
Raw materials
Preparation Products
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Ac-Arg-Leu-Arg-AMC Suppliers
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