talmapimod

Product Name: talmapimod
CAS No.: 309913-83-5
Chemical Name: talmapimod
Synonyms: SCIO 469;Scios 469;talmapimod;Unii-B1E00kq6nt;TalMapiMod (SCIO-469);SCIO 469 - Talmapimod;SCIO 469 hydrochloride;Talmapimod hydrochloride;TALMAPIMOD;SCIO469;SCIO 469;cytotoxicity,multiple,inhibit,tumor,SCIO 469,SCIO469,cells,Hsp27,Inhibitor,phosphorylation,Talmapimod,p38 MAPK,myeloma
CBNumber: CB81518535
Molecular Formula: C27H30ClFN4O3
Formula Weight: 513
MOL File: 309913-83-5.mol

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talmapimod Property

Boiling point:: 658.0±65.0 °C(Predicted)
Density: 1.29
storage temp.: Desiccate at +4°C
solubility: DMSO: soluble
form: A crystalline solid
pka: 6.52±0.70(Predicted)

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Safety

HS Code: 2924297099

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 29484
Product name: SCIO 469
Packaging: 1mg
Price: $33
Updated: 2024/03/01

Cayman Chemical

Product number: 29484
Product name: SCIO 469
Packaging: 5mg
Price: $120
Updated: 2024/03/01

Cayman Chemical

Product number: 29484
Product name: SCIO 469
Packaging: 10mg
Price: $223
Updated: 2024/03/01

Tocris

Product number: 3528
Product name: SCIO469hydrochloride
Purity: ≥98%(HPLC)
Packaging: 10
Price: $257
Updated: 2021/12/16

Tocris

Product number: 3528
Product name: SCIO469hydrochloride
Purity: ≥98%(HPLC)
Packaging: 50
Price: $1078
Updated: 2021/12/16

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talmapimod Chemical Properties,Usage,Production

Uses

Talmapimod is a p38 mitogen-activated protein (MAP) kinase inhibitor. Talmapimod reduced human myeloma cell growth in vivo both at early and advanced phases of the disease in mouse xenograft models. T almapimod that blocks tumor necrosis factor-α, interleukin-1β, and cyclooxygenase-2 synthesis in patients with active rheumatoid arthritis (RA)

Uses

Talmapimod is a p38 mitogen-activated protein (MAP) kinase inhibitor. Talmapimod reduced human myeloma cell growth in vivo both at early and advanced phases of the disease in mouse xenograft models. Talmapimod that blocks tumor necrosis factor-α, interleukin-1β, and cyclooxygenase-2 synthesis in patients with active rheumatoid arthritis (RA)

Definition

ChEBI: An indolecarboxamide obtained by formal condensation of the carboxy group of 6-chloro-3-[(dimethylamino)(oxo)acetyl]-1-methylindole-5-carboxylic acid with the secondary amino group of (2S,5R)-1-[(4-fluorophenyl)methyl]-2, -dimethylpiperazine. It is a potent inhibitor of MAPK and exhibits anti-cancer properties.

talmapimod Preparation Products And Raw materials

Raw materials

Preparation Products

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talmapimod Suppliers

Canada 1 China 59 India 1 United Kingdom 1 United States 10 Global 72

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2923
Advantage: 55

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15848
Advantage: 69

Chembest Research Laboratories Limited

Tel: 021-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6011
Advantage: 61

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15421
Advantage: 60

Tianjin Derchemist Science & Technology Co., Ltd.

Tel: 22-58627059 13920586291
Fax: 022-58620305
Email: zdcomcon@126.com
Country: China
ProdList: 2918
Advantage: 50

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7553
Advantage: 61

Shanghai Witofly Chemical Co.,Ltd

Tel
Email: sales@witofly.com
Country: China
ProdList: 2867
Advantage: 52

Jinan Mingya Medical Technology Co., Ltd.

Tel: 0531-85828981
Fax: +86-531-85806006
Email: 864598798@qq.com
Country: China
ProdList: 588
Advantage: 58

SPIRO PHARMA

Tel
Fax: -
Email: eric_feng1954@126.com
Country: China
ProdList: 9254
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9709
Advantage: 58

309913-83-5, talmapimodRelated Search:

TALMAPIMOD;SCIO469;SCIO 469

SCIO 469 - Talmapimod

talmapimod

6-Chloro-5-[[(2R,5S)-4-[(4-fluorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]carbonyl]-N,N,1-trimethyl-alpha-oxo-1H-indole-3-acetamide

Unii-B1E00kq6nt

6-Chloro-5-[[(2R,5S)-4-[(4-fluorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]carbonyl]-N,N,1-trimethyl-α-oxo-1H-Indole-3-acetamidehydrochloride

SCIO 469 hydrochloride

6-Chloro-5-[[(2R,5S)-4-[(4-fluorophenyl)Methyl]-2,5-diMethyl-1-piperazinyl]carbonyl]-N,N,1-triMethyl-α-oxo-1H-indole-3-acetaMide

SCIO 469

Scios 469

TalMapiMod (SCIO-469)

Talmapimod hydrochloride

1H-Indole-3-acetamide, 6-chloro-5-[[(2R,5S)-4-[(4-fluorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]carbonyl]-N,N,1-trimethyl-α-oxo-

cytotoxicity,multiple,inhibit,tumor,SCIO 469,SCIO469,cells,Hsp27,Inhibitor,phosphorylation,Talmapimod,p38 MAPK,myeloma

309913-83-5

C27H30ClFN4O3

C27H30ClFN4O3HCl