talmapimod

Product Name: talmapimod
CAS No.: 309913-83-5
Chemical Name: talmapimod
Synonyms: SCIO 469;Scios 469;talmapimod;Unii-B1E00kq6nt;TalMapiMod (SCIO-469);SCIO 469 - Talmapimod;SCIO 469 hydrochloride;Talmapimod hydrochloride;TALMAPIMOD;SCIO469;SCIO 469;cytotoxicity,multiple,inhibit,tumor,SCIO 469,SCIO469,cells,Hsp27,Inhibitor,phosphorylation,Talmapimod,p38 MAPK,myeloma
CBNumber: CB81518535
Molecular Formula: C27H30ClFN4O3
Formula Weight: 513
MOL File: 309913-83-5.mol

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talmapimod Property

Boiling point:: 658.0±65.0 °C(Predicted)
Density: 1.29
storage temp.: Desiccate at +4°C
solubility: DMSO: soluble
form: A crystalline solid
pka: 6.52±0.70(Predicted)
color: Pink to red

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Safety

HS Code: 2924297099

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 29484
Product name: SCIO 469
Packaging: 1mg
Price: $33
Updated: 2024/03/01

Cayman Chemical

Product number: 29484
Product name: SCIO 469
Packaging: 5mg
Price: $120
Updated: 2024/03/01

Cayman Chemical

Product number: 29484
Product name: SCIO 469
Packaging: 10mg
Price: $223
Updated: 2024/03/01

Tocris

Product number: 3528
Product name: SCIO469hydrochloride
Purity: ≥98%(HPLC)
Packaging: 10
Price: $257
Updated: 2021/12/16

Tocris

Product number: 3528
Product name: SCIO469hydrochloride
Purity: ≥98%(HPLC)
Packaging: 50
Price: $1078
Updated: 2021/12/16

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talmapimod Chemical Properties,Usage,Production

Uses

Talmapimod is a p38 mitogen-activated protein (MAP) kinase inhibitor. Talmapimod reduced human myeloma cell growth in vivo both at early and advanced phases of the disease in mouse xenograft models. Talmapimod that blocks tumor necrosis factor-α, interleukin-1β, and cyclooxygenase-2 synthesis in patients with active rheumatoid arthritis (RA)

Definition

ChEBI: An indolecarboxamide obtained by formal condensation of the carboxy group of 6-chloro-3-[(dimethylamino)(oxo)acetyl]-1-methylindole-5-carboxylic acid with the secondary amino group of (2S,5R)-1-[(4-fluorophenyl)methyl]-2, -dimethylpiperazine. It is a potent inhibitor of MAPK and exhibits anti-cancer properties.

talmapimod Preparation Products And Raw materials

Raw materials

Preparation Products

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talmapimod Suppliers

Canada 1 China 63 India 1 United Kingdom 1 United States 11 Global 77

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4660
Advantage: 60

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
Advantage: 58

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6391
Advantage: 58

TargetMol Chemicals Inc.

Tel
Email: support@targetmol.com
Country: United States
ProdList: 38631
Advantage: 58

Alfa Chemistry

Tel: --
Fax: --
Email: info@Alfa-Chemistry.com
Country: United States
ProdList: 6814
Advantage: 0

NE Scientific

Tel: --
Fax: --
Country: United States
ProdList: 5030
Advantage: 55

Cayman Chemical Company

Tel: --
Fax: --
Email: cayman@caymanchem.com
Country: United States
ProdList: 6213
Advantage: 81

United States Biological

Tel: --
Fax: --
Email: chemicals@usbio.net
Country: United States
ProdList: 6214
Advantage: 80

MedChemExpress

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Fax: --
Email: sales@medchemexpress.com
Country: United States
ProdList: 6398
Advantage: 58

Axon Medchem LLC

Tel: --
Fax: --
Email: info@axonmedchem.com
Country: United States
ProdList: 763
Advantage: 58

Santa Cruz Biotechnology, Inc.

Tel: --
Fax: --
Email: scbt@scbt.com
Country: United States
ProdList: 3597
Advantage: 60

309913-83-5, talmapimodRelated Search:

TALMAPIMOD;SCIO469;SCIO 469

SCIO 469 - Talmapimod

talmapimod

6-Chloro-5-[[(2R,5S)-4-[(4-fluorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]carbonyl]-N,N,1-trimethyl-alpha-oxo-1H-indole-3-acetamide

Unii-B1E00kq6nt

6-Chloro-5-[[(2R,5S)-4-[(4-fluorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]carbonyl]-N,N,1-trimethyl-α-oxo-1H-Indole-3-acetamidehydrochloride

SCIO 469 hydrochloride

6-Chloro-5-[[(2R,5S)-4-[(4-fluorophenyl)Methyl]-2,5-diMethyl-1-piperazinyl]carbonyl]-N,N,1-triMethyl-α-oxo-1H-indole-3-acetaMide

SCIO 469

Scios 469

TalMapiMod (SCIO-469)

Talmapimod hydrochloride

1H-Indole-3-acetamide, 6-chloro-5-[[(2R,5S)-4-[(4-fluorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]carbonyl]-N,N,1-trimethyl-α-oxo-

cytotoxicity,multiple,inhibit,tumor,SCIO 469,SCIO469,cells,Hsp27,Inhibitor,phosphorylation,Talmapimod,p38 MAPK,myeloma

309913-83-5

C27H30ClFN4O3

C27H30ClFN4O3HCl