ChemicalBook > CAS DataBase List > 3-(1,2-DIMETHYL-3-INDOLYL)-3-[4-(DIETHYLAMINO)-2-METHYLPHENYL]PHTHALIDE

3-(1,2-DIMETHYL-3-INDOLYL)-3-[4-(DIETHYLAMINO)-2-METHYLPHENYL]PHTHALIDE

Product Name
3-(1,2-DIMETHYL-3-INDOLYL)-3-[4-(DIETHYLAMINO)-2-METHYLPHENYL]PHTHALIDE
CAS No.
36499-49-7
Chemical Name
3-(1,2-DIMETHYL-3-INDOLYL)-3-[4-(DIETHYLAMINO)-2-METHYLPHENYL]PHTHALIDE
Synonyms
MB3;NC Blue 3;-(1,2-DIMETHYL-3-INDOLYL)-3-[4-(DIETHYLAMINO)-2-METHYLPHENYL]PHTHALIDE;3-(1,2-DIMETHYL-3-INDOLYL)-3-[4-(DIETHYLAMINO)-2-METHYLPHENYL]PHTHALIDE;(2R,3S)-rel-4-Methylene-5-oxo-2-propyltetrahydrofuran-3-carboxylic acid;3-[2-Methyl-4-(diethylamino)phenyl]-3-(1,2-dimethyl-3-indolyl)phthalide;2-(2'-Methyl-4'-diethylaminophenyl)-3-(1',2'-dimethylindol-3'-yl)phthalide;3-(1,2-Dimethyl-3-indolyl)-3-[4-(diethylamino)-2-methylphenyl]phthalide>3-[4-(Diethylamino)-2-methylphenyl]-3-(1,2-dimethyl-1H-indol-3-yl)phthalide;3-[4-(diethylamino)-2-methylphenyl]-3-(1,2-dimethylindol-3-yl)-2-benzofuran-1-one
CBNumber
CB8154725
Molecular Formula
C29H30N2O2
Formula Weight
438.56
MOL File
36499-49-7.mol
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3-(1,2-DIMETHYL-3-INDOLYL)-3-[4-(DIETHYLAMINO)-2-METHYLPHENYL]PHTHALIDE Property

Melting point:
217 °C
Boiling point:
627.3±55.0 °C(Predicted)
Density 
1.14
storage temp. 
-20°C
pka
6.27±0.50(Predicted)
form 
powder to crystal
color 
White to Light yellow
Water Solubility 
H2O: ≥10mg/mL
DMSO: ≥20mg/mL
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Safety

HS Code 
2933.99.8290
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M2449
Product name
MB-3
Purity
≥95% (HPLC)
Packaging
5MG
Price
$206
Updated
2024/03/01
Sigma-Aldrich
Product number
M2449
Product name
MB-3
Purity
≥95% (HPLC)
Packaging
25MG
Price
$812
Updated
2024/03/01
TCI Chemical
Product number
D3201
Product name
3-(1,2-Dimethyl-3-indolyl)-3-[4-(diethylamino)-2-methylphenyl]phthalide
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$42
Updated
2024/03/01
TCI Chemical
Product number
D3201
Product name
3-(1,2-Dimethyl-3-indolyl)-3-[4-(diethylamino)-2-methylphenyl]phthalide
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$213
Updated
2024/03/01
TRC
Product number
D493833
Product name
3-(4-(Diethylamino)-2-methylphenyl)-3-(1,2-dimethyl-1H-indol-3-yl)isobenzofuran-1(3H)-one
Packaging
100mg
Price
$60
Updated
2021/12/16
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3-(1,2-DIMETHYL-3-INDOLYL)-3-[4-(DIETHYLAMINO)-2-METHYLPHENYL]PHTHALIDE Chemical Properties,Usage,Production

Uses

MB-3 has been used as a general control non-repressible 5 (GCN5) inhibitor:

  • to study its effects on lamin A/C-associated pY19-Cav-2-mediated histone H3 acetylations
  • to analyze its effects on the growth of Arabidopsis thaliana seedlings
  • to study its effects on craniofacial chondrocyte maturation

Biological Activity

MB-3 can modify the gene expression in murine embryonic stem cells as well as yeast. It hinders the acetyltransferase activity of general control non-repressible 5 (GCN5) by binding to acetyl CoA pocket present in GCN5.', 'MB-3 is a Gcn5 H at (Histone Acetyltransferase) inhibitor; anti-inflammatory, anti-carcinogenic.

3-(1,2-DIMETHYL-3-INDOLYL)-3-[4-(DIETHYLAMINO)-2-METHYLPHENYL]PHTHALIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-(1,2-DIMETHYL-3-INDOLYL)-3-[4-(DIETHYLAMINO)-2-METHYLPHENYL]PHTHALIDE Suppliers

Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
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View Lastest Price from 3-(1,2-DIMETHYL-3-INDOLYL)-3-[4-(DIETHYLAMINO)-2-METHYLPHENYL]PHTHALIDE manufacturers

Career Henan Chemical Co
Product
3-(1,2-DIMETHYL-3-INDOLYL)-3-[4-(DIETHYLAMINO)-2-METHYLPHENYL]PHTHALIDE 36499-49-7
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2020-02-16

36499-49-7, 3-(1,2-DIMETHYL-3-INDOLYL)-3-[4-(DIETHYLAMINO)-2-METHYLPHENYL]PHTHALIDERelated Search:


  • 3-[4-(Diethylamino)-2-methylphenyl]-3-(1,2-dimethyl-1H-indol-3-yl)phthalide
  • 3-[4-(Diethylamino)-2-methylphenyl]-3-(1,2-dimethyl-1H-indole-3-yl)-1(3H)-isobenzofuranone
  • 3-(4-(diethylaMino)-2-Methylphenyl)-3-(1,2-diMethyl-1H-indol-3-yl)isobenzofuran-1(3H)-one
  • 2-(2'-Methyl-4'-diethylaminophenyl)-3-(1',2'-dimethylindol-3'-yl)phthalide
  • 3-[2-Methyl-4-(diethylamino)phenyl]-3-(1,2-dimethyl-3-indolyl)phthalide
  • MB3
  • 3-[2-Methyl-4-(diethylamino)phenyl]-3-(1,2-dimethyl-3-indolyl)phthalide 2-(2'-Methyl-4'-diethylaminophenyl)-3-(1',2'-dimethylindol-3'-yl)phthalide
  • (2R,3S)-rel-4-Methylene-5-oxo-2-propyltetrahydrofuran-3-carboxylic acid
  • 3-(1,2-DIMETHYL-3-INDOLYL)-3-[4-(DIETHYLAMINO)-2-METHYLPHENYL]PHTHALIDE
  • NC Blue 3
  • 3-[4-(Diethylamino)-2-methylphenyl]-3- (1,2-dimethyl-1H-indol-3-yl)-1(3H)-Isobenzofuranone
  • -(1,2-DIMETHYL-3-INDOLYL)-3-[4-(DIETHYLAMINO)-2-METHYLPHENYL]PHTHALIDE
  • 3-(1,2-Dimethyl-3-indolyl)-3-[4-(diethylamino)-2-methylphenyl]phthalide&gt
  • 1(3H)-Isobenzofuranone, 3-[4-(diethylamino)-2-methylphenyl]-3-(1,2-dimethyl-1H-indol-3-yl)-
  • 3-[4-(diethylamino)-2-methylphenyl]-3-(1,2-dimethylindol-3-yl)-2-benzofuran-1-one
  • 36499-49-7
  • Color Former & Related Compounds
  • Color Former
  • Color Former
  • Color Former & Related Compounds
  • Functional Materials