2-bromo-1-(4-bromo-2-fluorophenyl)ethanone
- Product Name
- 2-bromo-1-(4-bromo-2-fluorophenyl)ethanone
- CAS No.
- 869569-77-7
- Chemical Name
- 2-bromo-1-(4-bromo-2-fluorophenyl)ethanone
- Synonyms
- 4-Bromo-2-fluorophenacyl bromide;2-bromo-1-(4-bromo-2-fluorophenyl)ethanone;Ethanone, 2-bromo-1-(4-bromo-2-fluorophenyl)-;1-(4-Bromo-2-fluorophenyl)-2-bromo-1-ethanone
- CBNumber
- CB81557666
- Molecular Formula
- C8H5Br2FO
- Formula Weight
- 295.93
- MOL File
- 869569-77-7.mol
2-bromo-1-(4-bromo-2-fluorophenyl)ethanone Property
- Boiling point:
- 306.7±32.0 °C(Predicted)
- Density
- 1.914±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- crystalline powder
- color
- White
Safety
- HS Code
- 2914790090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H317May cause an allergic skin reaction
H319Causes serious eye irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B689548
- Product name
- 2-Bromo-1-(4-bromo-2-fluorophenyl)ethanone
- Packaging
- 100mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- B689548
- Product name
- 2-Bromo-1-(4-bromo-2-fluorophenyl)ethanone
- Packaging
- 500mg
- Price
- $175
- Updated
- 2021/12/16
- Product number
- B689548
- Product name
- 2-Bromo-1-(4-bromo-2-fluorophenyl)ethanone
- Packaging
- 1g
- Price
- $250
- Updated
- 2021/12/16
- Product number
- 096946
- Product name
- 2-Bromo-1-(4-bromo-2-fluorophenyl)ethanone
- Purity
- 95+%
- Packaging
- 1g
- Price
- $341
- Updated
- 2021/12/16
- Product number
- 2617-B-23
- Product name
- 4-Bromo-2-fluorophenacyl bromide
- Purity
- 98%
- Packaging
- 1g
- Price
- $192
- Updated
- 2021/12/16
2-bromo-1-(4-bromo-2-fluorophenyl)ethanone Chemical Properties,Usage,Production
Synthesis
625446-22-2
869569-77-7
Step 3: A solution of 2-bromo-1-(4-bromo-2-fluorophenyl)ethanone bromide (1.2 mL, 23.0 mmol) in 10 mL of glacial acetic acid was slowly added dropwise to a solution of 1-(4-bromo-2-fluorophenyl)ethanone (5.0 g, 23.0 mmol) in 150 mL of anhydrous methylene chloride, and the reaction was carried out at 0°C. After dropwise addition, the reaction mixture was slowly warmed up to room temperature. The progress of the reaction was monitored by TLC (unfolding agent: 5% ethyl acetate/hexane) to confirm complete consumption of the feedstock. The reaction mixture was diluted with dichloromethane and washed sequentially with 5% sodium thiosulfate solution and saturated saline. The organic layer was dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to afford 2-bromo-1-(4-bromo-2-fluorophenyl)ethanone (6.6 g, 97% yield) as a light green oil.
References
[1] Patent: US2008/45556, 2008, A1. Location in patent: Page/Page column 32-33
[2] Patent: WO2012/125926, 2012, A2. Location in patent: Page/Page column 79
[3] Patent: WO2012/122716, 2012, A1. Location in patent: Page/Page column 98
[4] Patent: CN107629023, 2018, A. Location in patent: Paragraph 0199; 0202; 0203; 0204
[5] Patent: CN107629022, 2018, A. Location in patent: Paragraph 0311; 0312; 0313; 0314
2-bromo-1-(4-bromo-2-fluorophenyl)ethanone Preparation Products And Raw materials
Raw materials
Preparation Products
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