ChemicalBook > CAS DataBase List > CATHEPSIN L

CATHEPSIN L

Product Name
CATHEPSIN L
Chemical Name
CATHEPSIN L
Synonyms
CATHEPSIN L;EC 3.4.22.15;Caspases 3&7;Magic Red™HUMAN CATHEPSIN-L;CATHEPSIN L (HUMAN);CATHEPSIN L, HUMAN LIVER
CBNumber
CB8167880
Formula Weight
0
MOL File
Mol file
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CATHEPSIN L Property

storage temp. 
−20°C
form 
solution
biological source
human liver
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Safety

Hazard Codes 
B
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
219402
Product name
Cathepsin L, Human Liver
Packaging
25μg
Price
$456
Updated
2025/07/31
Usbiological
Product number
144288
Product name
Cathepsin L
Packaging
100ug
Price
$490
Updated
2021/12/16
Usbiological
Product number
C2097-70
Product name
Cathepsin L
Packaging
1ml
Price
$596
Updated
2021/12/16
Usbiological
Product number
024015
Product name
Cathepsin L
Packaging
96Tests
Price
$809
Updated
2021/12/16
Usbiological
Product number
153936
Product name
Cathepsin L
Packaging
10ug
Price
$350
Updated
2021/12/16
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CATHEPSIN L Chemical Properties,Usage,Production

Uses

life science and biopharma

Biological Activity

Cathepsin L (CTSL) has higher activity than cathepsins B and H in the degradation of a variety of physiological protein substrates. It is believed to be responsible for the generation of endostatin from the NC1 domain in collagen XVII. It is responsible for regulating cell cycle, nucleotide-binding domain, leucine-rich–containing family, pyrin domain–containing-3 (NLRP3) inflammasome activation, proteolytic processing of Bid during apoptosis, and TGF-β signaling. It can degrade a wide range of proteins, encompassing enzymes, receptors, and transcription factors. Additionally, it produces active enzymes, receptors, and biologically active peptides through controlled proteolysis. Moreover, Cathepsin L has been observed to enhance tumor cell migration by lowering cell-cell adhesion and breaking down elements of the extracellular matrix. The expression of CTSL escalates in several types of cancers, including glioma, melanoma, pancreatic, prostate, and breast cancer. It plays a major role in the proteolysis of both cellular and endocytosed macromolecules.

CATHEPSIN L Preparation Products And Raw materials

Raw materials

Preparation Products

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CATHEPSIN L Suppliers

Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51395
Advantage
80
Shanghai Huzhen Industrial Co., LTD
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021-60345367 13916550749
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sales@shzbio.com
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China
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Merck Millipore
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1-400-889-1988 400-889-1988
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bioscience@merckgroup.com
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China
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Bio Rad Laboratories Inc
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Merck KGaA
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China
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CATHEPSIN LRelated Search:


  • HUMAN CATHEPSIN-L
  • EC 3.4.22.15
  • CATHEPSIN L
  • CATHEPSIN L (HUMAN)
  • CATHEPSIN L, HUMAN LIVER
  • Magic Red&#8482
  • Caspases 3&7
  • BioChemical
  • Cathepsins and Granzymes
  • Cell Signaling and Neuroscience
  • Cell Biology
  • Apoptosis and Cell Cycle
  • Enzymes