4-(PHENYLAMINO)PYRIDINE
- Product Name
- 4-(PHENYLAMINO)PYRIDINE
- CAS No.
- 22961-45-1
- Chemical Name
- 4-(PHENYLAMINO)PYRIDINE
- Synonyms
- AKOS BC-0724;4-ANILINOPYRIDINE;N-(4-Pyridyl)aniline;4-Anilinopyridine >N-phenyl-4-pyridinamine;phenyl-(4-pyridyl)amine;N-phenylpyridin-4-amine;4-(PHENYLAMINO)PYRIDINE;4-PYRIDINAMINE, N-PHENYL-;N-phenyl-N-(4-pyridinyl)amine
- CBNumber
- CB8172626
- Molecular Formula
- C11H10N2
- Formula Weight
- 170.21
- MOL File
- 22961-45-1.mol
4-(PHENYLAMINO)PYRIDINE Property
- Melting point:
- 177 °C
- Boiling point:
- 324.0±15.0 °C(Predicted)
- Density
- 1.144±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- soluble in Methanol
- form
- powder to crystalline
- pka
- 6.90±0.10(Predicted)
- color
- White to Orange to Green
Safety
- HazardClass
- IRRITANT
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- A2087
- Product name
- 4-Anilinopyridine
- Purity
- >99.0%(T)
- Packaging
- 5g
- Price
- $103
- Updated
- 2025/07/31
- Product number
- B521428
- Product name
- N-Phenylpyridin-4-amine
- Packaging
- 500mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- NP66702
- Product name
- N-Phenylpyridin-4-amine
- Packaging
- 10g
- Price
- $150
- Updated
- 2021/12/16
- Product number
- 063602
- Product name
- N-Phenylpyridin-4-amine
- Packaging
- 500mg
- Price
- $315
- Updated
- 2021/12/16
- Product number
- OR936810
- Product name
- 4-(Phenylamino)pyridine
- Purity
- 95%
- Packaging
- 5g
- Price
- $370
- Updated
- 2021/12/16
4-(PHENYLAMINO)PYRIDINE Chemical Properties,Usage,Production
Synthesis
1120-87-2
62-53-3
22961-45-1
The general procedure for the synthesis of N-phenylpyridin-4-amine from 4-bromopyridine and aniline was as follows: 3.16 g (20.0 mmol) of 4-bromopyridine, 2.79 g (30.0 mmol) of aniline, 0.37 g (0.4 mmol) of Pd2(dba)3, 0.08 g (0.4 mmol) of PtBu3 and 2.88 g (30.0 mmol ) KOtBu were dissolved in 60 mL of toluene to form a homogeneous solution. Subsequently, the reaction mixture was stirred at 85 °C for 4 hours. After completion of the reaction, the reaction solution was cooled to room temperature and extracted three times with 50 mL of water and 50 mL of diethyl ether. The organic phases were combined, dried with magnesium sulfate, and then the solvent was removed by rotary evaporation. Finally, the residue was separated and purified using silica gel column chromatography to afford 1.49 g of intermediate I-3 in 88% yield. The resulting compound was characterized by LC-MS.
References
[1] Patent: CN102850322, 2016, B. Location in patent: Paragraph 0150-0153
[2] Patent: CN108822041, 2018, A. Location in patent: Paragraph 0073; 0074; 0078
4-(PHENYLAMINO)PYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-(PHENYLAMINO)PYRIDINE manufacturers
- Product
- 4-(PHENYLAMINO)PYRIDINE 22961-45-1
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-06-03
- Product
- 4-(PHENYLAMINO)PYRIDINE 22961-45-1
- Price
- US $40.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 10 tons
- Release date
- 2023-09-12