ChemicalBook > CAS DataBase List > Amodiaquin dihydrochloride dihydrate

Amodiaquin dihydrochloride dihydrate

Product Name
Amodiaquin dihydrochloride dihydrate
CAS No.
6398-98-7
Chemical Name
Amodiaquin dihydrochloride dihydrate
Synonyms
AMODIAQUINE HCL;Amodiaquine HCLr;Amodiaquin Dihydrate;Amodiaquin HCl hydrate;AMODIAQUIN HYDROCHLORIDE;Dihydrochloride dihydrate;AMODIAQUIN DIHYDROCHLORIDE;AMODIAQUINE 2HCL DIHYDRATE;Amodiaquin diHCl dihydrate;AMODIAQUINE DIHYDROCHLORIDE
CBNumber
CB5156036
Molecular Formula
C20H25Cl2N3O2
Formula Weight
410.34
MOL File
6398-98-7.mol
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Amodiaquin dihydrochloride dihydrate Property

RTECS 
GO7300100
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Soluble in DMSO or methanol
form 
Solid
color 
White to Yellow to Orange
λmax
342nm(MeOH)(lit.)
Merck 
14,572
Stability:
Hygroscopic
InChI
InChI=1S/C20H22ClN3O.ClH.H2O/c1-3-24(4-2)13-14-11-16(6-8-20(14)25)23-18-9-10-22-19-12-15(21)5-7-17(18)19;;/h5-12,25H,3-4,13H2,1-2H3,(H,22,23);1H;1H2
InChIKey
AOFIMJMWPZOPAJ-UHFFFAOYSA-N
SMILES
N(C1C=CC(O)=C(CN(CC)CC)C=1)C1=CC=NC2=CC(Cl)=CC=C12.Cl.O
CAS DataBase Reference
6398-98-7(CAS DataBase Reference)
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Safety

WGK Germany 
3
HS Code 
2933492250
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR2344
Product name
AmodiaquineHydrochlorideHydrate
Purity
PharmaceuticalSecondaryStandard;CertifiedReferenceMaterial
Packaging
1G
Price
$205.2
Updated
2025/07/31
Sigma-Aldrich
Product number
CDS022953
Product name
Amodiaquin dihydrochloride dihydrate
Packaging
100 mg
Price
$44
Updated
2025/07/31
Sigma-Aldrich
Product number
A2799
Product name
Amodiaquin dihydrochloride dihydrate
Purity
analytical standard
Packaging
5g
Price
$41.1
Updated
2025/07/31
Sigma-Aldrich
Product number
1031004
Product name
Amodiaquine hydrochloride
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
500mg
Price
$393
Updated
2025/07/31
TCI Chemical
Product number
A3133
Product name
Amodiaquin Dihydrochloride Dihydrate
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$28
Updated
2025/07/31
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Amodiaquin dihydrochloride dihydrate Chemical Properties,Usage,Production

Chemical Properties

Light yellow powder

Uses

antimalarial

Uses

An anti-malarial quinoline derivative that acts as an histamine N-methyltransferase inhibitor

brand name

Camoquin (Parke-Davis).

Biological Activity

Amodiaquine is a potent, non-competitive inhibitor of histamine N-methyl transferase with estimated Ki of 18.6 nM. It is also used as an antimalarial and anti-inflammatory agent.

in vivo

In vivo administration of a small dose amodiaquine dramatically enhanced the effect of histamine on the gastric secretion in dogs. Amodiaquine prevents severe hepatic injury and high lethality in P. acnes-primed and LPS-induced hepatitis mice. Its treatment enhances the elevation of histamine in the liver of P. acnes-primed and LPS-induced hepatitis mice without accompanying tele-methyl histamine elevation.

IC 50

Plasmodium; Nurr1/NR4A2

Amodiaquin dihydrochloride dihydrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Amodiaquin dihydrochloride dihydrate Suppliers

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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76
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
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56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
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81
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
15883
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Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
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64
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9815
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Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
18270980682
Fax
021 51613951
Email
mlcheng@sunwaypharm.cn
Country
China
ProdList
8669
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Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
Country
China
ProdList
7247
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62
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
12952
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65
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
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View Lastest Price from Amodiaquin dihydrochloride dihydrate manufacturers

Wuhan Xinhao Biotechnology Co., Ltd
Product
Amodiaquine HCL 6398-98-7
Price
US $10.00-100.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000 Metric Ton/Month
Release date
2024-01-17
Career Henan Chemical Co
Product
Amodiaquin dihydrochloride dihydrate 6398-98-7
Price
US $1.00/KG
Min. Order
1KG
Purity
85.0-99.8%
Supply Ability
20tons
Release date
2020-01-08

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