Amodiaquin dihydrochloride dihydrate
- Product Name
- Amodiaquin dihydrochloride dihydrate
- CAS No.
- 6398-98-7
- Chemical Name
- Amodiaquin dihydrochloride dihydrate
- Synonyms
- AMODIAQUINE HCL;Amodiaquine HCLr;Amodiaquin Dihydrate;Amodiaquin HCl hydrate;AMODIAQUIN HYDROCHLORIDE;Dihydrochloride dihydrate;AMODIAQUIN DIHYDROCHLORIDE;AMODIAQUINE 2HCL DIHYDRATE;Amodiaquin diHCl dihydrate;AMODIAQUINE DIHYDROCHLORIDE
- CBNumber
- CB5156036
- Molecular Formula
- C20H25Cl2N3O2
- Formula Weight
- 410.34
- MOL File
- 6398-98-7.mol
Amodiaquin dihydrochloride dihydrate Property
- RTECS
- GO7300100
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Soluble in DMSO or methanol
- form
- Solid
- color
- White to Yellow to Orange
- λmax
- 342nm(MeOH)(lit.)
- Merck
- 14,572
- Stability:
- Hygroscopic
- InChI
- InChI=1S/C20H22ClN3O.ClH.H2O/c1-3-24(4-2)13-14-11-16(6-8-20(14)25)23-18-9-10-22-19-12-15(21)5-7-17(18)19;;/h5-12,25H,3-4,13H2,1-2H3,(H,22,23);1H;1H2
- InChIKey
- AOFIMJMWPZOPAJ-UHFFFAOYSA-N
- SMILES
- N(C1C=CC(O)=C(CN(CC)CC)C=1)C1=CC=NC2=CC(Cl)=CC=C12.Cl.O
- CAS DataBase Reference
- 6398-98-7(CAS DataBase Reference)
Safety
- WGK Germany
- 3
- HS Code
- 2933492250
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
N-Bromosuccinimide Price
- Product number
- PHR2344
- Product name
- AmodiaquineHydrochlorideHydrate
- Purity
- PharmaceuticalSecondaryStandard;CertifiedReferenceMaterial
- Packaging
- 1G
- Price
- $205.2
- Updated
- 2025/07/31
- Product number
- CDS022953
- Product name
- Amodiaquin dihydrochloride dihydrate
- Packaging
- 100 mg
- Price
- $44
- Updated
- 2025/07/31
- Product number
- A2799
- Product name
- Amodiaquin dihydrochloride dihydrate
- Purity
- analytical standard
- Packaging
- 5g
- Price
- $41.1
- Updated
- 2025/07/31
- Product number
- 1031004
- Product name
- Amodiaquine hydrochloride
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 500mg
- Price
- $393
- Updated
- 2025/07/31
- Product number
- A3133
- Product name
- Amodiaquin Dihydrochloride Dihydrate
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $28
- Updated
- 2025/07/31
Amodiaquin dihydrochloride dihydrate Chemical Properties,Usage,Production
Chemical Properties
Light yellow powder
Uses
antimalarial
Uses
An anti-malarial quinoline derivative that acts as an histamine N-methyltransferase inhibitor
brand name
Camoquin (Parke-Davis).
Biological Activity
Amodiaquine is a potent, non-competitive inhibitor of histamine N-methyl transferase with estimated Ki of 18.6 nM. It is also used as an antimalarial and anti-inflammatory agent.
in vivo
In vivo administration of a small dose amodiaquine dramatically enhanced the effect of histamine on the gastric secretion in dogs. Amodiaquine prevents severe hepatic injury and high lethality in P. acnes-primed and LPS-induced hepatitis mice. Its treatment enhances the elevation of histamine in the liver of P. acnes-primed and LPS-induced hepatitis mice without accompanying tele-methyl histamine elevation.
IC 50
Plasmodium; Nurr1/NR4A2
Amodiaquin dihydrochloride dihydrate Preparation Products And Raw materials
Raw materials
Preparation Products
Amodiaquin dihydrochloride dihydrate Suppliers
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View Lastest Price from Amodiaquin dihydrochloride dihydrate manufacturers
- Product
- Amodiaquine HCL 6398-98-7
- Price
- US $10.00-100.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 5000 Metric Ton/Month
- Release date
- 2024-01-17
- Product
- Amodiaquin dihydrochloride dihydrate 6398-98-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 85.0-99.8%
- Supply Ability
- 20tons
- Release date
- 2020-01-08