ChemicalBook > CAS DataBase List > Amodiaquin dihydrochloride dihydrate

Amodiaquin dihydrochloride dihydrate

Product Name
Amodiaquin dihydrochloride dihydrate
CAS No.
6398-98-7
Chemical Name
Amodiaquin dihydrochloride dihydrate
Synonyms
AMODIAQUINE HCL;Amodiaquine HCLr;Amodiaquin Dihydrate;Amodiaquin HCl hydrate;AMODIAQUIN HYDROCHLORIDE;Dihydrochloride dihydrate;AMODIAQUIN DIHYDROCHLORIDE;AMODIAQUINE 2HCL DIHYDRATE;Amodiaquin diHCl dihydrate;AMODIAQUINE DIHYDROCHLORIDE
CBNumber
CB5156036
Molecular Formula
C20H25Cl2N3O2
Formula Weight
410.34
MOL File
6398-98-7.mol
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Amodiaquin dihydrochloride dihydrate Property

RTECS 
GO7300100
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Soluble in DMSO or methanol
color 
White to Yellow to Orange
λmax
342nm(MeOH)(lit.)
Merck 
14,572
Stability:
Hygroscopic
CAS DataBase Reference
6398-98-7(CAS DataBase Reference)
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Safety

WGK Germany 
3
HS Code 
2933492250
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR2344
Product name
AmodiaquineHydrochlorideHydrate
Purity
PharmaceuticalSecondaryStandard;CertifiedReferenceMaterial
Packaging
1G
Price
$200
Updated
2024/03/01
Sigma-Aldrich
Product number
A2799
Product name
Amodiaquin dihydrochloride dihydrate
Purity
analytical standard
Packaging
5g
Price
$40.3
Updated
2024/03/01
Sigma-Aldrich
Product number
1031004
Product name
Amodiaquine hydrochloride
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
500mg
Price
$436
Updated
2024/03/01
TCI Chemical
Product number
A3133
Product name
Amodiaquin Dihydrochloride Dihydrate
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$28
Updated
2024/03/01
TCI Chemical
Product number
A3133
Product name
Amodiaquin Dihydrochloride Dihydrate
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$88
Updated
2024/03/01
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Amodiaquin dihydrochloride dihydrate Chemical Properties,Usage,Production

Chemical Properties

Light yellow powder

Uses

An anti-malarial quinoline derivative that acts as an histamine N-methyltransferase inhibitor

Uses

antimalarial

brand name

Camoquin (Parke-Davis).

Biological Activity

Amodiaquine is a potent, non-competitive inhibitor of histamine N-methyl transferase with estimated Ki of 18.6 nM. It is also used as an antimalarial and anti-inflammatory agent.

in vivo

In vivo administration of a small dose amodiaquine dramatically enhanced the effect of histamine on the gastric secretion in dogs. Amodiaquine prevents severe hepatic injury and high lethality in P. acnes-primed and LPS-induced hepatitis mice. Its treatment enhances the elevation of histamine in the liver of P. acnes-primed and LPS-induced hepatitis mice without accompanying tele-methyl histamine elevation.

Amodiaquin dihydrochloride dihydrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Amodiaquin dihydrochloride dihydrate Suppliers

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View Lastest Price from Amodiaquin dihydrochloride dihydrate manufacturers

Wuhan Xinhao Biotechnology Co., Ltd
Product
Amodiaquine HCL 6398-98-7
Price
US $10.00-100.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000 Metric Ton/Month
Release date
2024-01-17
Career Henan Chemical Co
Product
Amodiaquin dihydrochloride dihydrate 6398-98-7
Price
US $1.00/KG
Min. Order
1KG
Purity
85.0-99.8%
Supply Ability
20tons
Release date
2020-01-08

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