Lancovutide
- Product Name
- Lancovutide
- CAS No.
- 1391-36-2
- Chemical Name
- Lancovutide
- Synonyms
- Moli1901;DURAMYCIN;lancovutide;leucopeptin;Duramycin (~90%);cyclic6-19)-imine;antibioticpa48009;Lancovutide USP/EP/BP;duramycin from streptoverticillium*ci·Namoneus;duramycin from streptoverticillium*cinnamoneus
- CBNumber
- CB8177944
- Molecular Formula
- C89H125N23O25S3
- Formula Weight
- 2013.28
- MOL File
- 1391-36-2.mol
Lancovutide Property
- Melting point:
- 271-273 ºC
- Density
- 1.0238 (rough estimate)
- refractive index
- 1.6680 (estimate)
- storage temp.
- 2-8°C
- solubility
- 0.1 M HCl: soluble10mg/mL
- form
- powder
- pka
- 3.15±0.11(Predicted)
- color
- Off-White to Pale Yellow
- Sequence
- Cys-Lys-Gln-Cys-Cys-Ala-Phe-Gly-Pro-Phe-{Abu}-Phe-Val-Cys-Asp-Gly-Asn-{Abu}-Lys-NH2 (Disulfide bridge: Cys1-Abu18, Cys4-Cys14, Cys5-Abu11)
- Stability:
- Hygroscopic
- InChIKey
- BPIFGBWRBGTMHX-OHSSMEBINA-N
Safety
- WGK Germany
- 3
- RTECS
- BV7100000
N-Bromosuccinimide Price
- Product number
- D3168
- Product name
- Duramycin from Streptoverticillium cinnamoneus
- Purity
- ≥90.0%
- Packaging
- 10mg
- Price
- $535.6
- Updated
- 2025/07/31
- Product number
- D735023
- Product name
- Duramycin(~90%)
- Packaging
- 1mg
- Price
- $250
- Updated
- 2021/12/16
- Product number
- CHM0072930
- Product name
- DURAMYCIN
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496.31
- Updated
- 2021/12/16
Lancovutide Chemical Properties,Usage,Production
Uses
Duramycin is a chloride secretion enhancer in airway epithelium.
Synthesis
Duramycin is a natural product produced by certain bacteria that binds to phosphatidylethanolamine (PE). We report here the genes that are involved in duramycin biosynthesis, and we produced duramycin by expressing those genes in Escherichia coli. We show that duramycin analogs can also be produced.
in vivo
Evaluation of [68Ga]NODAGA-Duramycin as a positron emission tomography (PET) tracer of cell death for whole-body detection of chemotherapy-induced organ toxicity. Organ uptake is analyzed in untreated and doxorubicin, busulfan, and cisplatin-treated mice 2 h after intravenous injection of [68Ga]NODAGA-Duramycin. [68Ga]NODAGA-Duramycin PET/CT is successfully applied to non-invasively detect chemotherapy-induced organ toxicity with high sensitivity in mice[3].
Lancovutide Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Lancovutide manufacturers
- Product
- Lancovutide 1391-36-2
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-07-19