Maduramycin ammonium
Description- Product Name
- Maduramycin ammonium
- CAS No.
- 84878-61-5
- Chemical Name
- Maduramycin ammonium
- Synonyms
- Cygro;Maduramycin 1%;Maduramycin 90%;princin ammonoum;Prinicin ammonium;Madumixing ammonium;MADURAMYCIN AMMONIUM;MADURAMICIN AMMONIUM;Madubamycin ammonium;Maduraminic Ammonium
- CBNumber
- CB9703623
- Molecular Formula
- C47H83NO17
- Formula Weight
- 934.17
- MOL File
- 84878-61-5.mol
Maduramycin ammonium Property
- Melting point:
- 173-176 °C
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- DMF: 1 mg/ml
- form
- Solid
- color
- White to light yellow
- InChIKey
- WQGJEAMPBSZCIF-TVBLMVRVNA-N
Safety
- Hazard Codes
- T+
- Risk Statements
- 25-27-36
- Safety Statements
- 26-28-36/37-45
- RIDADR
- UN 2811
- WGK Germany
- 3
- HazardClass
- 6.1
- PackingGroup
- III
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H319Causes serious eye irritation
- Precautionary statements
-
P262Do not get in eyes, on skin, or on clothing.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 34069
- Product name
- Maduramicin ammonium
- Purity
- VETRANAL?, analytical standard
- Packaging
- 100mg
- Price
- $115
- Updated
- 2025/07/31
- Product number
- M110000
- Product name
- Maduramicin ammonium
- Packaging
- 100mg
- Price
- $135
- Updated
- 2021/12/16
- Product number
- 257343
- Product name
- Maduramicin ammonium
- Packaging
- 10mg
- Price
- $326
- Updated
- 2021/12/16
- Product number
- PST0000321
- Product name
- MADURAMICIN AMMONIUM
- Purity
- 95.00%
- Packaging
- 100MG
- Price
- $704.55
- Updated
- 2021/12/16
- Product number
- PST0000321
- Product name
- MADURAMICIN AMMONIUM
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $1593.9
- Updated
- 2021/12/16
Maduramycin ammonium Chemical Properties,Usage,Production
Description
Maduramycin ammonium salt is a white crystalline powder with a melting point of 165-167°C. It is insoluble in water and soluble in organic solvents. Because of its broad anticoccidial spectrum and not easy to develop drug resistance, it is widely used. The dosage is very small. At present, our country stipulates that the amount of maduramycin ammonium salt added to the feed for preventing chicken coccidiosis is 5mg/kg.
Chemical Properties
White Solid
Uses
Maduramcin ammonium is prepared from maduramicin by taking advantage of the acidic carboxylic acid which ionises and readily forms the salt in ammonium hydroxide solutions. The ammonium salt is the preferred formulation in animals to prevent coccidiosis and to promote growth. Maduramicin is also active against Treponema and Cryptosporidium. Maduramicin is an ionophore, forming complexes with monovalent cations, with a higher affinity for K+ than Na+.
Uses
Maduramicin ammonium is prepared from maduramicin by taking advantage of the acidic carboxylic acid which ionises and readily forms the salt in ammonium hydroxide solutions. The ammonium salt is the preferred formulation in animals to prevent coccidiosis and to promote growth. Maduramicin is also active against Treponema and Cryptosporidium. Maduramicin is an ionophore, forming complexes with monovalent cations, with a higher affinity for K+ than Na+.
Uses
Polyether antibiotic chemically related to the lonomycins. Coccidiostat
Definition
ChEBI: Maduramicin is a glycoside.
in vivo
| Animal Model: | ICR mouse (Maduramicin-induced rhabdomyolysis model)[3] |
| Dosage: | 3.5, 7 mg/kg |
| Administration: | Oral gavage (p.o.), once daily for 7 days |
| Result: | Significantly reduced body weight, increased AST, ALT, LDH, BUN, and CK levels; Caused that liver exhibited vacuolar degeneration, kidney showed renal tubular epithelial cell shedding, and myocardial and skeletal muscle fibers were disorganized and partially lysed. |
| Animal Model: | Wistar rats (Maduramicin-induced skeletal muscle injury model) |
| Dosage: | 1.75, 3.5, 7 mg/kg |
| Administration: | Oral gavage (p.o.), once daily for 7 days |
| Result: | Dose-dependently increased LC3-II and p62 protein levels in skeletal muscle, indicating impaired autophagic flux; Upregulated eIF2α phosphorylation and ATF4 expression, activating endoplasmic reticulum stress; Increased AMPK phosphorylation, suggesting activation of the AMPK signaling pathway. |
Maduramycin ammonium Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Maduramycin ammonium manufacturers
- Product
- Maduramycin ammonium 84878-61-5
- Price
- US $1.00-4.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1KG 100K
- Release date
- 2025-05-19
- Product
- Maduramycin ammonium 84878-61-5
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-10-25
- Product
- Maduramycin Ammonium 84878-61-5
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1000kg
- Release date
- 2024-04-07