Bromoacetyl bromide Property

Melting point:

148.5°C (estimate)

Boiling point:

147-150 °C(lit.)

Density 

2.324 g/mL at 20 °C

vapor pressure 

3.8 mm Hg ( 25 °C)

refractive index 

n20/D 1.547(lit.)

Flash point:

>105°C

storage temp. 

Refrigerator (+4°C)

solubility 

soluble in Chloroform

form 

Powder

color 

White

Water Solubility 

REACTS

Sensitive 

Moisture Sensitive

BRN 

605440

Dielectric constant

12.6（20℃）

Stability:

Stable, but reacts violently with water. Incompatible with water, moisture, alcohols, strong bases, strong oxidizing agents.

InChIKey

LSTRKXWIZZZYAS-UHFFFAOYSA-N

LogP

-0.04 at 25℃

CAS DataBase Reference

598-21-0(CAS DataBase Reference)

NIST Chemistry Reference

Bromoacetyl bromide(598-21-0)

EPA Substance Registry System

Acetyl bromide, 2-bromo- (598-21-0)

Safety

Hazard Codes 

C

Risk Statements 

34-14

Safety Statements 

26-36/37/39-45-8-30-25

RIDADR 

UN 2513 8/PG 2

WGK Germany 

3

F 

10-19

TSCA 

Yes

HazardClass 

8

PackingGroup 

II

HS Code 

29159080

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

P405Store locked up.

Bromoacetyl bromide Chemical Properties,Usage,Production

Chemical Properties

dark brown-yellow liquid

Uses

Bromoacetyl bromide is widely used in the synthesis of fine chemicals, agrochemicals, dyes and pharmaceuticals. As an acylating agent, it reacts with 10H-phenothiazine to give 10-bromoacetyl-10H-phenothiazine. Similarly, it is also involved in the preparation of bromoactylated starch which is a biodegradable thermoplastic copolymer.

General Description

A water-white liquid with a pungent odor. Denser than water. Irritates skin, eyes and mucous membranes. May be toxic by ingestion, inhalation and skin absorption. Used to make other chemicals.

Air & Water Reactions

Fumes in air. Reacts violently with water to form hydrobromic acid (HBr) (USCG 1991).

Reactivity Profile

Bromoacetyl bromide is incompatible with water, with bases (including amines), with strong oxidizing agents, with alcohols. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291]. Decomposes when heated with evolution of highly toxic and irritating hydrogen bromide and bromophosgene vapors.

Health Hazard

Inhalation causes severe irritation of upper respiratory system. External contact causes severe irritation of eyes and skin. Ingestion causes severe irritation of mouth and stomach.