2-chloro-5H-pyrrolo[2,3-b]pyrazine

Uses

Product Name: 2-chloro-5H-pyrrolo[2,3-b]pyrazine
CAS No.: 889447-19-2
Chemical Name: 2-chloro-5H-pyrrolo[2,3-b]pyrazine
Synonyms: 2-chloro-5H-pyrrolo[2;2-Chloro-5H-pyrrolo[2,3-b...;2-chloro-5H-pyrrolo[2,3-b]pyrazine;2-chloro-5H-pyrrolo[3,2-b]pyrazine;5H-Pyrrolo[2,3-b]pyrazine, 2-chloro-
CBNumber: CB81856095
Molecular Formula: C6H4ClN3
Formula Weight: 153.57
MOL File: 889447-19-2.mol

More

Less

2-chloro-5H-pyrrolo[2,3-b]pyrazine Property

Density: 1.531±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 10.63±0.50(Predicted)
Appearance: yellow solid
InChI: InChI=1S/C6H4ClN3/c7-5-3-9-6-4(10-5)1-2-8-6/h1-3H,(H,8,9)
InChIKey: RORAIVYFQFAIAF-UHFFFAOYSA-N
SMILES: C12NC=CC1=NC(Cl)=CN=2

More

Less

Safety

HS Code: 2933998090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TRC

Product number: C384408
Product name: 2-Chloro-5H-pyrrolo[2,3-B]pyrazine
Packaging: 100mg
Price: $130
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC144247
Product name: 2-Chloro-5H-pyrrolo[2,3-b]pyrazine
Packaging: 50mg
Price: $150
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC144247
Product name: 2-Chloro-5H-pyrrolo[2,3-b]pyrazine
Packaging: 10mg
Price: $50
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC144247
Product name: 2-Chloro-5H-pyrrolo[2,3-b]pyrazine
Packaging: 25mg
Price: $100
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H32-5-C5
Product name: 2-Chloro-5H-pyrrolo[2,3-b]pyrazine
Packaging: 250mg
Price: $225
Updated: 2021/12/16

More

Less

2-chloro-5H-pyrrolo[2,3-b]pyrazine Chemical Properties,Usage,Production

Uses

2-Chloro-5H-pyrrolo[2,3-B]pyrazine is a common pyrrolo[2,3-B]pyrazine bicyclic compound, widely used in the preparation of pharmaceutical and chemical intermediates.

Synthesis

875781-43-4

889447-19-2

General procedure for the synthesis of 2-chloro-5H-pyrrolo[2,3-b]pyrazine from 5-bromo-4,7-diazaindole: 2-bromo-5H-pyrrolo[2,3-b]pyrazine (3.1 g, 16 mmol) was dissolved in 1,4-dioxane (20 mL), and phosphorochloridic acid (2.27 mL, 24.1 mmol) was added. Subsequently, triethylamine (220 μL, 1.58 mmol) was added and the reaction was carried out at 110 °C for 6 hours. After completion of the reaction, the reaction mixture was dried with anhydrous sodium sulfate and concentrated. Purification by column chromatography (petroleum ether/ethyl acetate, v/v=2/1) gave 1.3 g of gray solid product in 54% yield.

References

[1] Patent: CN106336413, 2017, A. Location in patent: Paragraph 0379; 0380; 0381

2-chloro-5H-pyrrolo[2,3-b]pyrazine Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

2-chloro-5H-pyrrolo[2,3-b]pyrazine Suppliers

China 87 Germany 1 India 1 United Kingdom 1 United States 8 Global 98

Changzhou Xuanye Technology Co., Ltd

Tel: 15195022192
Email: 279776773@qq.com
Country: China
ProdList: 1996
Advantage: 58

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Shangchem Co., Ltd.

Tel: +86-21-68182121
Fax: +86-21-68182121
Country: China
ProdList: 882
Advantage: 52

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11035
Advantage: 64

Kohn & Shawn Pharmatech Co.,Ltd

Tel: 0931-4190454 13893344397
Fax: +86-931-8506154
Email: sales@kyxpharma.com
Country: China
ProdList: 310
Advantage: 55

Dtchem Laboratories,（Gan Su）Co.,Ltd.

Tel: 18993966060
Fax: 0943-8288977
Email: sales@techbiochem.com
Country: China
ProdList: 806
Advantage: 61

NovoChemy Ltd.

Tel: 021-31261262/ 49 (0)17662837245
Fax: (0)21-33250524
Email: sales@novochemy.com
Country: Germany
ProdList: 6328
Advantage: 58

Nanjing Norris-Pharm Technology Co., Ltd

Tel: 18652989687
Fax: +86-25-52131256
Email: sales@norris-pharm.com
Country: China
ProdList: 8878
Advantage: 55

More

Less

View Lastest Price from 2-chloro-5H-pyrrolo[2,3-b]pyrazine manufacturers

Career Henan Chemical Co

Product: 2-chloro-5H-pyrrolo[2,3-b]pyrazine 889447-19-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2020-01-03

889447-19-2, 2-chloro-5H-pyrrolo[2,3-b]pyrazineRelated Search:

2-chloro-5H-pyrrolo[2,3-b]pyrazine

2-Chloro-5H-pyrrolo[2,3-b...

2-chloro-5H-pyrrolo[2

5H-Pyrrolo[2,3-b]pyrazine, 2-chloro-

2-chloro-5H-pyrrolo[3,2-b]pyrazine

889447-19-2

CHIRAL CHEMICALS