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HUMAN IGF-II

Description Source Background
Product Name
HUMAN IGF-II
CAS No.
96081-16-2
Chemical Name
HUMAN IGF-II
Synonyms
IGF-II;RHIGF-II;IGF-2 HUMAN;HUMAN IGF-II;IGF-II, HUMAN;Somatamedin A;RH-IGF-II HUMAN;HUMAN SOMATAMEDIN A;RECOMBINANT HUMAN IGF-II;REC IGF-II (1-67) (HUMAN)
CBNumber
CB8192859
Molecular Formula
C24H36N4O9
Formula Weight
0
MOL File
Mol file
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HUMAN IGF-II Property

storage temp. 
-20°C
form 
lyophilized powder
biological source
human
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Safety

WGK Germany 
3
Storage Class
11 - Combustible Solids
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
I8904
Product name
Insulin-like Growth Factor-II from mouse
Purity
IGF-II, recombinant, expressed in <I>E. coli</I>, lyophilized powder
Packaging
50 μg
Price
$360
Updated
2026/03/19
Sigma-Aldrich
Product number
SRP3070
Product name
IGF-II human
Purity
recombinant, expressed in <I>E. coli</I>, &#8805;98% (SDS-PAGE), &#8805;98% (HPLC), suitable for cell culture
Packaging
50 μg
Price
$402
Updated
2026/03/19
Sigma-Aldrich
Product number
I8904
Product name
Insulin-like Growth Factor-II from mouse
Purity
IGF-II, recombinant, expressed in <I>E. coli</I>, lyophilized powder
Packaging
5 x 50 μg
Price
$1470
Updated
2026/03/19
Sigma-Aldrich
Product number
I2526
Product name
Insulin-like Growth Factor-II human
Purity
IGF-II, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
Packaging
50μG
Price
$327
Updated
2026/03/19
Sigma-Aldrich
Product number
I2526
Product name
Insulin-like Growth Factor-II human
Purity
IGF-II, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
Packaging
5X50μG
Price
$1020
Updated
2023/01/07
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HUMAN IGF-II Chemical Properties,Usage,Production

Biochem/physiol Actions

Insulin-like growth factor II (IGF-II) also known as multiplication stimulating activity (MSA), shows virtually identical bioactivities as IGF-I. Expression of IGF-II is highest in fetal tissues, where it is believed to play a major role in overall growth and development. After birth IGF-II expression decreases to much lower levels in a variety of tissues. IGF-II is produced also in several tumors. IGF-II binds to IGF-II receptor (IGF-IIR), to IGF-IR and weakly to the insulin receptor (IR). All IGF-II bioactivities in adult tissues are generally attributed to its interaction with IGF-IR. However, during embryogenesis the roles of both IGF-IIR and IR may be significant in promoting normal growth.

Description

Insulin-Like Growth Factor- II Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 67 amino acids and having a molecular mass of 7.5k Dalton.                  

IGF-II is purified by proprietary chromatographic techniques.

Source

Escherichia Coli

Background

IGF-2 is a member of the INS family of polypeptide growth factors that is involved in development and growth. It is an imprinted gene and is expressed only from the paternally inherited allele. It is a candidate gene for eating disorders. There is a read-through, INS-IGF2, which aligns to this gene at the 3' region and to the upstream INS gene at the 5' region. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

HUMAN IGF-II Preparation Products And Raw materials

Raw materials

Preparation Products

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HUMAN IGF-II Suppliers

GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
12952
Advantage
65
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51395
Advantage
80
Creative Peptides
Tel
Email
info@creative-peptides.com
Country
United States
ProdList
6083
Advantage
56
Nanjing Peptide Biotech Ltd.
Tel
025-58361106-805 15951641583
Fax
025-58361106-806
Email
zhao.xu@njpeptide.com
Country
China
ProdList
9979
Advantage
55
Gill polypeptide biopharmaceutical (dalian) co., LTD
Tel
021-61263455 13167021076
Email
amy@glschina.com
Country
China
ProdList
9867
Advantage
58
Chengdu Jinglin Biotechnology Co., Ltd.
Tel
17711399154
Email
3211919385@qq.com
Country
China
ProdList
1815
Advantage
58
Shanghai Yingxin Laboratory Equipment Co., Ltd.
Tel
021-59178156 17002132182
Email
3146474380@qq.com
Country
China
ProdList
10000
Advantage
58

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