ChemicalBook > CAS DataBase List > (R)-(-)-3-Chloro-1,2-propanediol

(R)-(-)-3-Chloro-1,2-propanediol

Product Name
(R)-(-)-3-Chloro-1,2-propanediol
CAS No.
57090-45-6
Chemical Name
(R)-(-)-3-Chloro-1,2-propanediol
Synonyms
(R)-3-CHLOROPROPANE-1,2-DIOL;(R)-3-CHLORO-1,2-PROPANEDIOL;2-propanediol;(R)-3-ChL;(R)-3-MCPD;(R)-(-)-3-Chloro-1;R-Chloropropanediol;oro-1,2-propanedioL;(R)-(-)-3-Chloro-1,2;Panthenol 16485-10-2
CBNumber
CB8194510
Molecular Formula
C3H7ClO2
Formula Weight
110.54
MOL File
57090-45-6.mol
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(R)-(-)-3-Chloro-1,2-propanediol Property

Melting point:
-40°C
Boiling point:
213 °C(lit.)
alpha 
-0.9 º (neat)
Density 
1.321 g/mL at 20 °C(lit.)
vapor pressure 
0.04 mm Hg ( 25 °C)
refractive index 
n20/D 1.48(lit.)
Flash point:
>230 °F
storage temp. 
Inert atmosphere,2-8°C
solubility 
soluble in Chloroform, Methanol
form 
clear liquid
pka
13.28±0.20(Predicted)
Specific Gravity
1.322
color 
Colorless to Brown
optical activity
[α]20/D 1°, neat
Water Solubility 
soluble
BRN 
2202928
InChIKey
SSZWWUDQMAHNAQ-VKHMYHEASA-N
LogP
0.5 at 25℃
CAS DataBase Reference
57090-45-6(CAS DataBase Reference)
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Safety

Hazard Codes 
T
Risk Statements 
25-41-68-62-36/37/38-23/25-21
Safety Statements 
26-28-39-45-36/37/39
RIDADR 
UN 2689 6.1/PG 3
WGK Germany 
3
RTECS 
TY4025000
F 
3
HazardClass 
6.1
PackingGroup 
III
HS Code 
29053200
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H290May be corrosive to metals

H301Toxic if swalloed

H315Causes skin irritation

H318Causes serious eye damage

H330Fatal if inhaled

H351Suspected of causing cancer

H370Causes damage to organs

H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P234Keep only in original container.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
540056
Product name
(R)-(?)-3-Chloro-1,2-propanediol
Purity
97%, optical purity ee: 98% (GLC)
Packaging
5g
Price
$34.92
Updated
2024/03/01
TCI Chemical
Product number
M0967
Product name
(R)-(-)-3-Chloro-1,2-propanediol
Purity
>96.0%(GC)
Packaging
10g
Price
$77
Updated
2024/03/01
TCI Chemical
Product number
M0967
Product name
(R)-(-)-3-Chloro-1,2-propanediol
Purity
>96.0%(GC)
Packaging
25g
Price
$138
Updated
2024/03/01
Alfa Aesar
Product number
L18555
Product name
(R)-(-)-3-Chloro-1,2-propanediol, 97%, ee 98%
Packaging
5g
Price
$58.65
Updated
2024/03/01
Alfa Aesar
Product number
L18555
Product name
(R)-(-)-3-Chloro-1,2-propanediol, 97%, ee 98%
Packaging
1g
Price
$23.5
Updated
2021/12/16
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(R)-(-)-3-Chloro-1,2-propanediol Chemical Properties,Usage,Production

Chemical Properties

clear light yellow liquid

Uses

(R)-(-)-3-Chloro-1,2-propanediol is used as a reagent in the synthesis of PA-824, which is a promising antituberculosis drug candidate that has been synthesized. It is also used in the manufacture of L-carnitine, which is a quaternary ammonium compound involved in metabolism in most mammals, plants, and some bacteria.

Definition

ChEBI: The (R)-stereoisomer of 3-chloro-1,2-propanediol.

Health Hazard

The toxicological evaluation revealed that (R)-(-)-3-Chloro-1,2-propanediol was genotoxic in humans and had anti-fertility effects in male rats. The discharge of this compound into wastewater might cause serious environmental hazards[1].

References

[1] Yun‐Xu Yang. “Practical and Efficient Utilisation of (R)-3-chloro-1,2-Propanediol in Synthesis of L-Carnitine.” Journal of Chemical Research-s 93 1 (2011): 371–372.

(R)-(-)-3-Chloro-1,2-propanediol Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-(-)-3-Chloro-1,2-propanediol Suppliers

Americas 1 Canada 2 China 295 Europe 4 France 2 Germany 9 India 13 Japan 9 Norway 1 Slovakia 1 South Korea 5 Switzerland 2 The Netherlands 2 United Kingdom 18 United States 51 Global 415
Interchim SA
Tel
--
Fax
--
Email
him@interchim.com
Country
France
ProdList
2725
Advantage
58
Interchim S.A.
Tel
--
Fax
--
Email
interchim@interchim.com
Country
France
ProdList
6302
Advantage
76
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View Lastest Price from (R)-(-)-3-Chloro-1,2-propanediol manufacturers

hebei hongtan Biotechnology Co., Ltd
Product
(R)-(-)-3-Chloro-1,2-propanediol 57090-45-6
Price
US $30.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
2000kg
Release date
2024-05-14
Hebei Chuanghai Biotechnology Co,.LTD
Product
(R)-3-Chloro-1,2-propanediol 57090-45-6
Price
US $10.00/KG
Min. Order
1KG
Purity
99.%
Supply Ability
10 ton
Release date
2024-07-30
Henan Fengda Chemical Co., Ltd
Product
(R)-3-Chloro-1,2-propanediol 57090-45-6
Price
US $9.00-0.90/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-23

57090-45-6, (R)-(-)-3-Chloro-1,2-propanediolRelated Search:

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