ChemicalBook > CAS DataBase List > TYRPHOSTIN B44

TYRPHOSTIN B44

Product Name
TYRPHOSTIN B44
CAS No.
133550-32-0
Chemical Name
TYRPHOSTIN B44
Synonyms
AG 527;Zinc03871437;TYRPHOSTIN B44;TRYPHOSTIN AG 527;TYRPHOSTIN B44(-);TYRPHOSTIN AG 527;Reaxys ID: 4356230;ALPHA-CYANO-(-)-(R)-N-(ALPHA-PHENETHYL)-3,4-DIHYDROXYCINNAMIDE;(-)-(r)-n-(α-methylbenzyl)-3,4-dihydroxybenzylidenecyanoacetamide;(-)-(R)-N-(ALPHA-METHYLBENZYL)-3,4-DIHYDROXYBENZYLIDINECYANOACETAMIDE
CBNumber
CB8197102
Molecular Formula
C18H16N2O3
Formula Weight
308.33
MOL File
133550-32-0.mol
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TYRPHOSTIN B44 Property

Boiling point:
603.0±55.0 °C(Predicted)
Density 
1.299±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
DMSO or ethanol: soluble
form 
Yellow solid.
pka
8.81±0.10(Predicted)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
T947983
Product name
TyrphostinB44,(-)enantiomer
Packaging
5mg
Price
$40
Updated
2021/12/16
TRC
Product number
T947983
Product name
TyrphostinB44,(-)enantiomer
Packaging
50mg
Price
$255
Updated
2021/12/16
Usbiological
Product number
256987
Product name
Tyrphostin B44,
Packaging
10mg
Price
$366
Updated
2021/12/16
Usbiological
Product number
256986
Product name
Tyrphostin B44,
Packaging
10mg
Price
$366
Updated
2021/12/16
TRC
Product number
T947983
Product name
TyrphostinB44,(-)enantiomer
Packaging
100mg
Price
$475
Updated
2021/12/16
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TYRPHOSTIN B44 Chemical Properties,Usage,Production

Uses

Tyrphostin B44, (-) enantiomer is a potent inhibitor of (EGFR) kinase.

Biological Activity

Potent inhibitor of epidermal growth factor receptor (EGFR) kinase (IC 50 = 0.4 μ M), more active than the (+) enantiomer ((S)-(E)-2-Cyano-3-(3',4'-dihydroxyphenyl)-N-(1-phenylethyl)-2-propenamide ). Selective over ErbB2.

TYRPHOSTIN B44 Preparation Products And Raw materials

Raw materials

Preparation Products

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TYRPHOSTIN B44 Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
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Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35906
Advantage
56
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11605
Advantage
64
VDM Biochemicals
Tel
0330-2528181
Fax
0330-2528171
Email
sales@vdmbio.com
Country
United States
ProdList
510
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64
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9664
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60
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14059
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65
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8449
Advantage
60
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9709
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131981
Advantage
58

133550-32-0, TYRPHOSTIN B44Related Search:


  • (R)-(E)-2-CYANO-3-(3',4'-DIHYDROXYPHENYL)-N-(1-PHENYLETHYL)-2-PROPENAMIDE
  • (-)-(R)-N-(ALPHA-METHYLBENZYL)-3,4-DIHYDROXY-BENZYLIDENECYANOACETAMIDE
  • (-)-(R)-N-(ALPHA-METHYLBENZYL)-3,4-DIHYDROXYBENZYLIDINECYANOACETAMIDE
  • TYRPHOSTIN AG 527
  • TYRPHOSTIN B44
  • TYRPHOSTIN B44(-)
  • TRYPHOSTIN AG 527
  • (E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1R)-1-phenylethyl]-2-propenamide
  • AG 527
  • ALPHA-CYANO-(-)-(R)-N-(ALPHA-PHENETHYL)-3,4-DIHYDROXYCINNAMIDE
  • (-)-(r)-n-(α-methylbenzyl)-3,4-dihydroxybenzylidenecyanoacetamide
  • Tyrphostin B44, (-)-(R)-N-(α-Methylbenzyl)-3,4-dihydroxybenzylidenecyanoacetamide
  • Zinc03871437
  • Reaxys ID: 4356230
  • 2-Propenamide, 2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1R)-1-phenylethyl]-, (2E)-
  • 133550-32-0
  • BioChemical
  • Cell Signaling and Neuroscience
  • Cell Biology
  • Receptor Tyrosine Kinase Inhibitors
  • Epidermal Growth Factor Receptor (EGFR)
  • Kinase/Phosphatase Biology
  • Intracellular Signaling
  • Protein Kinase