TYRPHOSTIN B44

Product Name: TYRPHOSTIN B44
CAS No.: 133550-32-0
Chemical Name: TYRPHOSTIN B44
Synonyms: AG 527;Zinc03871437;TYRPHOSTIN B44;TRYPHOSTIN AG 527;TYRPHOSTIN B44(-);TYRPHOSTIN AG 527;Reaxys ID: 4356230;ALPHA-CYANO-(-)-(R)-N-(ALPHA-PHENETHYL)-3,4-DIHYDROXYCINNAMIDE;(-)-(r)-n-(α-methylbenzyl)-3,4-dihydroxybenzylidenecyanoacetamide;(-)-(R)-N-(ALPHA-METHYLBENZYL)-3,4-DIHYDROXYBENZYLIDINECYANOACETAMIDE
CBNumber: CB8197102
Molecular Formula: C18H16N2O3
Formula Weight: 308.33
MOL File: 133550-32-0.mol

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TYRPHOSTIN B44 Property

Boiling point:: 603.0±55.0 °C(Predicted)
Density: 1.299±0.06 g/cm3(Predicted)
storage temp.: −20°C
solubility: DMSO or ethanol: soluble
form: Yellow solid.
pka: 8.81±0.10(Predicted)

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Safety

Safety Statements: 22-24/25
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: T947983
Product name: TyrphostinB44,(-)enantiomer
Packaging: 5mg
Price: $40
Updated: 2021/12/16

TRC

Product number: T947983
Product name: TyrphostinB44,(-)enantiomer
Packaging: 50mg
Price: $255
Updated: 2021/12/16

Usbiological

Product number: 256987
Product name: Tyrphostin B44,
Packaging: 10mg
Price: $366
Updated: 2021/12/16

Usbiological

Product number: 256986
Product name: Tyrphostin B44,
Packaging: 10mg
Price: $366
Updated: 2021/12/16

TRC

Product number: T947983
Product name: TyrphostinB44,(-)enantiomer
Packaging: 100mg
Price: $475
Updated: 2021/12/16

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TYRPHOSTIN B44 Chemical Properties,Usage,Production

Uses

Tyrphostin B44, (-) enantiomer is a potent inhibitor of (EGFR) kinase.

Biological Activity

Potent inhibitor of epidermal growth factor receptor (EGFR) kinase (IC 50 = 0.4 μ M), more active than the (+) enantiomer ((S)-(E)-2-Cyano-3-(3',4'-dihydroxyphenyl)-N-(1-phenylethyl)-2-propenamide ). Selective over ErbB2.

TYRPHOSTIN B44 Preparation Products And Raw materials

Raw materials

Preparation Products

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TYRPHOSTIN B44 Suppliers

China 12 Europe 1 Germany 3 Switzerland 3 United Kingdom 5 United States 11 Global 35

BIOTREND GmbH

Tel: --
Fax: --
Email: jaeger@biotrend.com
Country: Germany
ProdList: 249
Advantage: 65

BIOTREND Chemicals AG

Tel: --
Fax: --
Email: info@biotrend.ch
Country: Germany
ProdList: 1250
Advantage: 62

Service Chemical Inc.

Tel: --
Fax: --
Email: sales@chemos-group.com
Country: Germany
ProdList: 6350
Advantage: 71

133550-32-0, TYRPHOSTIN B44Related Search:

TYRPHOSTIN B44, (+) ENANTIOMER N1-ISOPROPYL-2-CYANOACETAMIDE D,L-N-(ALPHA-PHENYLETHYL) METHACRYLAMIDE AG 99 3-(1-PHENYLETHYLAMINO)PROPANENITRILE TYRPHOSTIN B44 (R)-(+)-N-ALLYL-ALPHA-METHYLBENZYLAMINE& N-ISOPROPYLMETHACRYLAMIDE AG 490 BENZYL-((E)-3-PHENYL-ALLYL)-AMINE

(R)-(E)-2-CYANO-3-(3',4'-DIHYDROXYPHENYL)-N-(1-PHENYLETHYL)-2-PROPENAMIDE

(-)-(R)-N-(ALPHA-METHYLBENZYL)-3,4-DIHYDROXY-BENZYLIDENECYANOACETAMIDE

(-)-(R)-N-(ALPHA-METHYLBENZYL)-3,4-DIHYDROXYBENZYLIDINECYANOACETAMIDE

TYRPHOSTIN AG 527

TYRPHOSTIN B44

TYRPHOSTIN B44(-)

TRYPHOSTIN AG 527

(E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1R)-1-phenylethyl]-2-propenamide

AG 527

ALPHA-CYANO-(-)-(R)-N-(ALPHA-PHENETHYL)-3,4-DIHYDROXYCINNAMIDE

(-)-(r)-n-(α-methylbenzyl)-3,4-dihydroxybenzylidenecyanoacetamide

Tyrphostin B44, (-)-(R)-N-(α-Methylbenzyl)-3,4-dihydroxybenzylidenecyanoacetamide

Zinc03871437

Reaxys ID: 4356230

2-Propenamide, 2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1R)-1-phenylethyl]-, (2E)-

133550-32-0

BioChemical

Cell Signaling and Neuroscience

Cell Biology

Receptor Tyrosine Kinase Inhibitors

Epidermal Growth Factor Receptor (EGFR)

Kinase/Phosphatase Biology

Intracellular Signaling

Protein Kinase