5-BROMO-2-PHENOXYPYRIMIDINE
- Product Name
- 5-BROMO-2-PHENOXYPYRIMIDINE
- CAS No.
- 257280-25-4
- Chemical Name
- 5-BROMO-2-PHENOXYPYRIMIDINE
- Synonyms
- 5-BROMO-2-PHENOXYPYRIMIDINE;Pyrimidine, 5-bromo-2-phenoxy-;5-BROMO-2-PHENOXYPYRIMIDINE ISO 9001：2015 REACH
- CBNumber
- CB8203520
- Molecular Formula
- C10H7BrN2O
- Formula Weight
- 251.08
- MOL File
- 257280-25-4.mol
5-BROMO-2-PHENOXYPYRIMIDINE Property
- storage temp.
- Sealed in dry,Room Temperature
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B687403
- Product name
- 5-Bromo-2-phenoxypyrimidine
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- 072020
- Product name
- 5-Bromo-2-phenoxypyrimidine
- Purity
- 95+%
- Packaging
- 1g
- Price
- $185
- Updated
- 2021/12/16
- Product number
- W4908
- Product name
- 5-Bromo-2-phenoxypyrimidine
- Packaging
- 25g
- Price
- $280
- Updated
- 2021/12/16
- Product number
- FB140721
- Product name
- 5-Bromo-2-phenoxypyrimidine
- Packaging
- 25g
- Price
- $382
- Updated
- 2021/12/16
- Product number
- 37958
- Product name
- 5-Bromo-2-phenoxypyrimidine
- Purity
- 95+%
- Packaging
- 5G
- Price
- $399
- Updated
- 2021/12/16
5-BROMO-2-PHENOXYPYRIMIDINE Chemical Properties,Usage,Production
Synthesis
183438-24-6
108-95-2
257280-25-4
Step A: Synthesis of 5-bromo-2-phenoxypyrimidine 5-Bromo-2-iodopyrimidine (Bridge Organics, 1.01 g, 3.57 mmol), phenol (Aldrich, 3.35 g, 35.7 mmol) and potassium carbonate (Aldrich, 4.93 g, 35.7 mmol) were mixed under nitrogen protection and the reaction was stirred for 4 hr at 165°C. Upon completion of the reaction, the mixture was cooled to room temperature, followed by liquid-liquid partition extraction with ethyl acetate (250 mL) and 1N hydrochloric acid (4 × 200 mL). The organic phase was washed with 1N hydrochloric acid until the aqueous phase was colorless. The organic phase was separated and washed sequentially with water (100 mL) and saturated saline (100 mL). The organic layer was dried over anhydrous magnesium sulfate and concentrated under reduced pressure to give an orange oily crude product (1.1 g). The crude product was purified by fast silica gel column chromatography using an 80 g Silicycle silica gel column with 10% ethyl acetate in hexane solution as eluent to afford the target compound 5-bromo-2-phenoxypyrimidine as a white solid (0.82 g, 92% yield). Thin layer chromatography (TLC) analysis showed an Rf value of 0.51 (unfolding agent: hexane-ethyl acetate, 8:2 v/v). Product characterization data: 1H-NMR (400 MHz, CDCl3) δ 8.56 (s, 2H), 7.46-7.41 (m, 2H), 7.30-7.24 (m, 1H), 7.20-7.16 (m, 2H); Mass spectrum (APCI+) m/z 252.9 (M + 1).
References
[1] Patent: US2010/75990, 2010, A1. Location in patent: Page/Page column 40
[2] Patent: CN108069974, 2018, A. Location in patent: Paragraph 0194-0196
5-BROMO-2-PHENOXYPYRIMIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-BROMO-2-PHENOXYPYRIMIDINE manufacturers
- Product
- 5-BROMO-2-PHENOXYPYRIMIDINE 257280-25-4
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-12-01
- Product
- 5-BROMO-2-PHENOXYPYRIMIDINE 257280-25-4
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 5-BROMO-2-PHENOXYPYRIMIDINE 257280-25-4
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09