ChemicalBook > CAS DataBase List > PROTOPORPHYRINATO ZINC

PROTOPORPHYRINATO ZINC

Product Name: PROTOPORPHYRINATO ZINC
CAS No.: 15442-64-5
Chemical Name: PROTOPORPHYRINATO ZINC
Synonyms: ZnPP;PROTOPORPHYRINATO ZINC;Protoporphyrin IX Zinc;Zinc protoporphyrin trihydrate;Zinc Protoporphyrin, 10 mM in DMSO;Zinc protoporphyrin trihydrate, 95+%;PROTOPORPHYRINATO ZINC ISO 9001：2015 REACH;Zinc Protoporphyrin IX DISCONTINUED, offer Z439970;Zinc (II) Protoporphyrin IX - CAS 15442-64-5 - Calbiochem;Zinc(II) 3,3'-(3,8,13,17-tetramethyl-7,12-divinylporphyrin-2,18-diyl)dipropionate
CBNumber: CB8208833
Molecular Formula: C34H31N4O4Zn-
Formula Weight: 625.03
MOL File: 15442-64-5.mol

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PROTOPORPHYRINATO ZINC Property

RTECS: ZG9210300
storage temp.: Inert atmosphere,2-8°C
solubility: DMSO : 50 mg/mL (79.87 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form: Crystalline
color: Dark red to purple
Water Solubility: Insoluble in water. Soluble in ethanol, and DMSO, pyridine, or dimethyl formamide.
λmax: 426 nm
ε(extinction coefficient): ≥10000 at 585-591nm in pyridine
≥12000 at 548-554nm in pyridine
≥135000 at 423-429nm in pyridine
Stability:: Hygroscopic
InChIKey: FUTVBRXUIKZACV-RGGAHWMASA-K
SMILES: C(C1C(=C2C=C3C(C=C)=C(C)C4C=C5C(C=C)=C(C)C6=CC7C(C)=C(CCC(=O)[O-])C8N=7[Zn+2]([N-]56)(N3=4)[N-]2C=1C=8)C)CC(=O)[O-].[H+]
EPA Substance Registry System: Zincate(2-), [7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-.kappa.N21,.kappa.N22,.kappa.N23,.kappa.N24]-, dihydrogen, (SP-4-2)- (15442-64-5)

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Safety

WGK Germany: 3
TSCA: Yes

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 691550-M
Product name: Zinc (II) Protoporphyrin IX - CAS 15442-64-5 - Calbiochem
Purity: A potent and selective inhibitor of heme oxygenase, the enzyme which generates carbon monoxide (CO) and biliverdin.
Packaging: 25mg
Price: $103
Updated: 2025/07/31

Sigma-Aldrich

Product number: 282820
Product name: Protoporphyrin IX zinc(II)
Purity: guanylate cyclase inhibitor
Packaging: 50mg
Price: $227
Updated: 2025/07/31

Sigma-Aldrich

Product number: 282820
Product name: Protoporphyrin IX zinc(II)
Purity: guanylate cyclase inhibitor
Packaging: 250mg
Price: $739.44
Updated: 2025/07/31

Cayman Chemical

Product number: 14483
Product name: Zinc Protoporphyrin-9
Purity: ≥98%
Packaging: 10mg
Price: $34
Updated: 2024/03/01

Cayman Chemical

Product number: 14483
Product name: Zinc Protoporphyrin-9
Purity: ≥98%
Packaging: 25mg
Price: $71
Updated: 2024/03/01

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PROTOPORPHYRINATO ZINC Chemical Properties,Usage,Production

Uses

Zinc Protoporphyrin is a metabolite formed during biosynthesis and is used to evaluate iron nutrition and metabolism.

General Description

A potent and selective inhibitor of heme oxygenase, the enzyme which generates carbon monoxide (CO) and biliverdin. Inhibits soluble guanylyl cyclase and produces a time- and concentration-dependent inactivation of all three isoforms of nitric oxide synthase (IC₅₀ = 800 nM, 4 μM, and 5 μM for nNOS, iNOS, and eNOS, respectively). Inhibits relaxation induced by acetylcholine, ANP, and VIP in isolated rat aorta. Blocks interleukin-1 and prevents induction of long-term potentiation. Also useful as an indicator of iron-deficient erythropoiesis. Does not cross the blood-brain barrier.

Biological Activity

Inhibitor of heme oxygenase, which generates the putative neurotransmitter CO.

Biochem/physiol Actions

Primary Targetheme oxygenase

in vivo

Zinc Protoporphyrin (12.5, 25, 50 mg/kg for i.p.; 12.5, 50 mg/kg for p.o.; from day 7 to 19) exerts dose-dependent antitumor effects manifested by the retardation of tumor growth^[3].

Animal Model:	BALB/c mice inoculated with C-26 cells^[3]
Dosage:	12.5, 25, 50 mg/kg for i.p.; 12.5, 50 mg/kg for p.o.
Administration:	IP or PO; from day 7 to 19
Result:	Exerted dose-dependent antitumor effects manifested by the retardation of tumor growth.

IC 50

Human Endogenous Metabolite

PROTOPORPHYRINATO ZINC Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from PROTOPORPHYRINATO ZINC manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: Zinc protoporphyrin 15442-64-5
Price: US $18.00-48.00/KG
Min. Order: 0.01KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2025-06-19

Shaanxi Dideu Medichem Co. Ltd

Product: Zinc protoporphyrin 15442-64-5
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99.0%+
Supply Ability: 100 tons
Release date: 2019-12-30

15442-64-5, PROTOPORPHYRINATO ZINCRelated Search:

Protoporphyrin IX 2,3,4,5-TETRAMETHYLPYRROLE Allylacetic acid ZINC NITRATE, TETRAHYDRATE 2,4-Dimethylpyrrole 2,5-Dimethyl-1H-pyrrole PROTOPORPHYRINATO ZINC 4-HEXENOIC ACID 3-BUTEN-1-AMINE 6-Heptenoic acid 3-METHYL-2-BUTEN-1-AMINE 1,3,6-HEPTATRIENE N-PROPYLETHYLIDENEAMINE 3,4-DIMETHYLPYRROLE 5-METHYL-4-HEXENOIC ACID 2,4-OCTADIENE HEPTA-4,6-DIENOIC ACID 3-ETHYL-2-METHYL-2-PENTENE

PROTOPORPHYRINATO ZINC

dihydrogen [3,8,13,17-tetramethyl-7,12-divinyl-21H,23H-porphine-2,18-dipropionato(4-)-N21,N22,N23,N24]zincate(4-)

Zinc protoporphyrin trihydrate

Zinc protoporphyrin trihydrate, 95+%

Zinc (II) Protoporphyrin IX - CAS 15442-64-5 - Calbiochem

ZnPP

PROTOPORPHYRINATO ZINC ISO 9001：2015 REACH

Zinc Protoporphyrin IX DISCONTINUED, offer Z439970

Zinc(II) 3,3'-(3,8,13,17-tetramethyl-7,12-divinylporphyrin-2,18-diyl)dipropionate

screening,Zinc Protoporphyrin9,heme,iron,inhibit,Phloroglucinol,deficiency,anti-cancer,Reactive Oxygen Species,Inhibitor,marker,Zinc Protoporphyrin,Apoptosis,H2O2,Endogenous Metabolite,HO-1,oxygenase-1,Zinc Protoporphyrin 9

Zinc Protoporphyrin, 10 mM in DMSO

3-[18-(2-carboxyethyl)-8,13-bis(ethenyl)-3,7,12,17-tetramethylporphyrin-21,24-diid-2-yl]propanoic acid

Protoporphyrin IX Zinc

15442-64-5

C34H32N4O4Zn

Natural Porphyrins and Derivitives

Porphyrins

metal porphine (porphyrin) complex