1-(2-Bromoethyl)-4-(trifluoromethyl)benzene, 2-(4-Trifluoromethylphenyl)ethyl bromide
- Product Name
- 1-(2-Bromoethyl)-4-(trifluoromethyl)benzene, 2-(4-Trifluoromethylphenyl)ethyl bromide
- CAS No.
- 130365-87-6
- Chemical Name
- 1-(2-Bromoethyl)-4-(trifluoromethyl)benzene, 2-(4-Trifluoromethylphenyl)ethyl bromide
- Synonyms
- 4-TrifluoroMethylphenyl)ethyl broMide;4-(Trifluoromethyl)phenethyl bromide;2-(4-trifluoromethylphenyl)ethyl bromide;4-(TrifluoroMethyl)phenethyl broMide 97%;1-(2-broMoethyl)-4-(trifluoroMethyl)benzene;Benzene, 1-(2-bromoethyl)-4-(trifluoromethyl)-;1-(2-Bromoethyl)-4-(trifluoromethyl)benzene, 2-(4-Trifluoromethylphenyl)ethyl bromide
- CBNumber
- CB82096863
- Molecular Formula
- C9H8BrF3
- Formula Weight
- 253.06
- MOL File
- 130365-87-6.mol
1-(2-Bromoethyl)-4-(trifluoromethyl)benzene, 2-(4-Trifluoromethylphenyl)ethyl bromide Property
- Boiling point:
- 218.0±35.0 °C(Predicted)
- Density
- 1.499 g/mL at 25 °C
- refractive index
- n20/D 1.487
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- liquid
- Appearance
- Colorless to light yellow Liquid
Safety
- Hazard Codes
- Xn,N
- Risk Statements
- 22-36-51/53
- Safety Statements
- 26-61
- RIDADR
- UN 3082 9/PG 3
- WGK Germany
- 3
- HS Code
- 2903998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 692050
- Product name
- 4-(Trifluoromethyl)phenethyl bromide
- Purity
- 97%
- Packaging
- 1g
- Price
- $105
- Updated
- 2025/07/31
- Product number
- 1124AQ
- Product name
- 4-(Trifluoromethyl)phenethyl bromide
- Packaging
- 1g
- Price
- $110
- Updated
- 2021/12/16
- Product number
- HCH0066516
- Product name
- 4-(TRIFLUOROMETHYL)PHENETHYL BROMIDE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $610
- Updated
- 2021/12/16
- Product number
- HCH0066516
- Product name
- 4-(TRIFLUOROMETHYL)PHENETHYL BROMIDE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $648.83
- Updated
- 2021/12/16
- Product number
- HCH0066516
- Product name
- 4-(TRIFLUOROMETHYL)PHENETHYL BROMIDE
- Purity
- 95.00%
- Packaging
- 10G
- Price
- $680
- Updated
- 2021/12/16
1-(2-Bromoethyl)-4-(trifluoromethyl)benzene, 2-(4-Trifluoromethylphenyl)ethyl bromide Chemical Properties,Usage,Production
Synthesis
2968-93-6
130365-87-6
Step ii: Synthesis of 1-(2-bromoethyl)-4-(trifluoromethyl)benzene To a 50 mL round bottom flask was added 2-(4-(trifluoromethyl)phenyl)ethanol (7.9 g, 0.0415 mol) and phosphorus tribromide (5.6 g, 0.0207 mol). The reaction mixture was stirred at 100 °C for 2 hours. After completion of the reaction, the reaction was quenched by adding ice-cold water to the mixture. The reaction mixture was extracted with hexane and the organic layer was separated. The organic layer was washed with brine and dried over anhydrous sodium sulfate. The solvent was removed by concentration under reduced pressure to give the crude product. The crude product was purified by column chromatography using 60-120 mesh silica gel as stationary phase and 0-5% ethyl acetate in hexane solution as eluent to give 4-(trifluoromethyl)phenylethyl bromide (7.8 g, 74% yield). 1H NMR (300 MHz, CDCl3): δ 7.60 (d, 2H), 7.35 (d, 2H), 3.61 (t, 2H), 3.25 (t, 2H).
References
[1] Patent: WO2015/101928, 2015, A1. Location in patent: Page/Page column 127;
[2] Patent: WO2005/123748, 2005, A1. Location in patent: Page/Page column 97-98
[3] Patent: WO2005/49613, 2005, A1. Location in patent: Page/Page column 48-49
[4] Patent: WO2007/69986, 2007, A1. Location in patent: Page/Page column 87
1-(2-Bromoethyl)-4-(trifluoromethyl)benzene, 2-(4-Trifluoromethylphenyl)ethyl bromide Preparation Products And Raw materials
Raw materials
Preparation Products
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