ChemicalBook > CAS DataBase List > 1-(2-Bromoethyl)-4-(trifluoromethyl)benzene, 2-(4-Trifluoromethylphenyl)ethyl bromide

1-(2-Bromoethyl)-4-(trifluoromethyl)benzene, 2-(4-Trifluoromethylphenyl)ethyl bromide

Product Name
1-(2-Bromoethyl)-4-(trifluoromethyl)benzene, 2-(4-Trifluoromethylphenyl)ethyl bromide
CAS No.
130365-87-6
Chemical Name
1-(2-Bromoethyl)-4-(trifluoromethyl)benzene, 2-(4-Trifluoromethylphenyl)ethyl bromide
Synonyms
4-TrifluoroMethylphenyl)ethyl broMide;4-(Trifluoromethyl)phenethyl bromide;2-(4-trifluoromethylphenyl)ethyl bromide;4-(TrifluoroMethyl)phenethyl broMide 97%;1-(2-broMoethyl)-4-(trifluoroMethyl)benzene;Benzene, 1-(2-bromoethyl)-4-(trifluoromethyl)-;1-(2-Bromoethyl)-4-(trifluoromethyl)benzene, 2-(4-Trifluoromethylphenyl)ethyl bromide
CBNumber
CB82096863
Molecular Formula
C9H8BrF3
Formula Weight
253.06
MOL File
130365-87-6.mol
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1-(2-Bromoethyl)-4-(trifluoromethyl)benzene, 2-(4-Trifluoromethylphenyl)ethyl bromide Property

Boiling point:
218.0±35.0 °C(Predicted)
Density 
1.499 g/mL at 25 °C
refractive index 
n20/D 1.487
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
liquid
Appearance
Colorless to light yellow Liquid
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Safety

Hazard Codes 
Xn,N
Risk Statements 
22-36-51/53
Safety Statements 
26-61
RIDADR 
UN 3082 9/PG 3
WGK Germany 
3
HS Code 
2903998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
692050
Product name
4-(Trifluoromethyl)phenethyl bromide
Purity
97%
Packaging
1g
Price
$105
Updated
2025/07/31
AK Scientific
Product number
1124AQ
Product name
4-(Trifluoromethyl)phenethyl bromide
Packaging
1g
Price
$110
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0066516
Product name
4-(TRIFLUOROMETHYL)PHENETHYL BROMIDE
Purity
95.00%
Packaging
5G
Price
$610
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0066516
Product name
4-(TRIFLUOROMETHYL)PHENETHYL BROMIDE
Purity
95.00%
Packaging
1G
Price
$648.83
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0066516
Product name
4-(TRIFLUOROMETHYL)PHENETHYL BROMIDE
Purity
95.00%
Packaging
10G
Price
$680
Updated
2021/12/16
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1-(2-Bromoethyl)-4-(trifluoromethyl)benzene, 2-(4-Trifluoromethylphenyl)ethyl bromide Chemical Properties,Usage,Production

Synthesis

2968-93-6

130365-87-6

Step ii: Synthesis of 1-(2-bromoethyl)-4-(trifluoromethyl)benzene To a 50 mL round bottom flask was added 2-(4-(trifluoromethyl)phenyl)ethanol (7.9 g, 0.0415 mol) and phosphorus tribromide (5.6 g, 0.0207 mol). The reaction mixture was stirred at 100 °C for 2 hours. After completion of the reaction, the reaction was quenched by adding ice-cold water to the mixture. The reaction mixture was extracted with hexane and the organic layer was separated. The organic layer was washed with brine and dried over anhydrous sodium sulfate. The solvent was removed by concentration under reduced pressure to give the crude product. The crude product was purified by column chromatography using 60-120 mesh silica gel as stationary phase and 0-5% ethyl acetate in hexane solution as eluent to give 4-(trifluoromethyl)phenylethyl bromide (7.8 g, 74% yield). 1H NMR (300 MHz, CDCl3): δ 7.60 (d, 2H), 7.35 (d, 2H), 3.61 (t, 2H), 3.25 (t, 2H).

References

[1] Patent: WO2015/101928, 2015, A1. Location in patent: Page/Page column 127;
[2] Patent: WO2005/123748, 2005, A1. Location in patent: Page/Page column 97-98
[3] Patent: WO2005/49613, 2005, A1. Location in patent: Page/Page column 48-49
[4] Patent: WO2007/69986, 2007, A1. Location in patent: Page/Page column 87

1-(2-Bromoethyl)-4-(trifluoromethyl)benzene, 2-(4-Trifluoromethylphenyl)ethyl bromide Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(2-Bromoethyl)-4-(trifluoromethyl)benzene, 2-(4-Trifluoromethylphenyl)ethyl bromide Suppliers

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130365-87-6, 1-(2-Bromoethyl)-4-(trifluoromethyl)benzene, 2-(4-Trifluoromethylphenyl)ethyl bromideRelated Search:


  • 1-(2-Bromoethyl)-4-(trifluoromethyl)benzene, 2-(4-Trifluoromethylphenyl)ethyl bromide
  • 2-(4-trifluoromethylphenyl)ethyl bromide
  • 4-(Trifluoromethyl)phenethyl bromide
  • 4-TrifluoroMethylphenyl)ethyl broMide
  • 1-(2-broMoethyl)-4-(trifluoroMethyl)benzene
  • 4-(TrifluoroMethyl)phenethyl broMide 97%
  • Benzene, 1-(2-bromoethyl)-4-(trifluoromethyl)-
  • 130365-87-6
  • 130365876