3β-Hydroxyurs-12,19-dien-28-oic acid
- Product Name
- 3β-Hydroxyurs-12,19-dien-28-oic acid
- CAS No.
- 6812-98-2
- Chemical Name
- 3β-Hydroxyurs-12,19-dien-28-oic acid
- Synonyms
- Ursa-12;Sanguisorbigenin;3β-Hydroxyurs-12;Tomentosolic acid;19-dien-28-oic acid;19-Dehydroursolic acid;Ursa-12,19-dien-28-oic acid;3β-Hydroxyurs-12,19-dien-28-oic acid;3β-Hydroxyurs-12,19-dien-28-oic acid;Ursa-12,19-dien-28-oic acid, 3-hydroxy-, (3β)-
- CBNumber
- CB82143356
- Molecular Formula
- C30H46O3
- Formula Weight
- 454.7
- MOL File
- 6812-98-2.mol
3β-Hydroxyurs-12,19-dien-28-oic acid Property
- Melting point:
- 267-268 °C (decomp)
- Boiling point:
- 563.4±50.0 °C(Predicted)
- Density
- 1.11±0.1 g/cm3(Predicted)
- pka
- 4.49±0.70(Predicted)
- form
- Solid
- color
- White to off-white
N-Bromosuccinimide Price
- Product number
- CFN91139
- Product name
- Sanguisorbigenin
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $413
- Updated
- 2021/12/16
3β-Hydroxyurs-12,19-dien-28-oic acid Chemical Properties,Usage,Production
Biological Activity
Sanguisorbigenin is a natural antibacterial agent that inhibits methicillin-resistant S. aureus (MRSA)[1]. The minimal inhibitory concentration values of Sanguisorbigenin against six strains of S. aureus are in the range of 12.5-50 μg/mL[1]. The expression of blaR1, mecA and blaZ is significantly inhibited in MRSA in a dose-dependent manner when it is treated with sub-MIC (1.56-6.25 μg/mL) concentrations of Sanguisorbigenin. Sanguisorbigenin remarkably reduces the gene expression of mecA. Sanguisorbigenin has a potent antibacterial effect and could effectively reverse the sense of antibiotics by inhibiting the mecA expression and decrease PBP2a expression[1].
References
[1]. S Wang, et al. Antibacterial activity and synergy of antibiotics with sanguisorbigenin isolated from Sanguisorba officinalis L. against methicillin-resistant Staphylococcus aureus. Lett Appl Microbiol. 2021 Mar;72(3):238-244.
3β-Hydroxyurs-12,19-dien-28-oic acid Preparation Products And Raw materials
Raw materials
Preparation Products
3β-Hydroxyurs-12,19-dien-28-oic acid Suppliers
- Tel
- 021-51320588
- Fax
- 0086-21-51320502
- tauto@tautobiotech.com
- Country
- China
- ProdList
- 3989
- Advantage
- 66
- Tel
- 028-81700200 18116577057
- Fax
- 028-81705658
- 3003855609@qq.com
- Country
- China
- ProdList
- 7887
- Advantage
- 56
- Tel
- 0510-85629785 18013409632
- Fax
- 051085625359
- sales@reading-chemicals.com
- Country
- China
- ProdList
- 15178
- Advantage
- 58
- Tel
- 18607101326 15172504745
- Fax
- +86-27-84254680
- aileen@chemfaces.com
- Country
- China
- ProdList
- 7057
- Advantage
- 55
- Tel
- 021-65675885 18964387627
- Fax
- 021-65675885
- info@efebio.com
- Country
- China
- ProdList
- 9806
- Advantage
- 58
- Tel
- 4009903999 13395398332
- Fax
- 0539-6365991
- sales@xiyashiji.com
- Country
- China
- ProdList
- 20806
- Advantage
- 60
- Tel
- 028-85370565-229 18080489829
- 3004654993@qq.com
- Country
- China
- ProdList
- 8908
- Advantage
- 60
- Tel
- 021-57127007-6622 17621252073
- Fax
- +86 (21) 5132-0077
- luzh@nature-standard.com
- Country
- China
- ProdList
- 3021
- Advantage
- 58
- Tel
- 025-025-51191215 18013836722
- Fax
- 025-51191215
- 2399235533@qq.com
- Country
- China
- ProdList
- 4933
- Advantage
- 58
- Tel
- 028-87075086 18030859262
- 2851503756@qq.com
- Country
- China
- ProdList
- 1926
- Advantage
- 58