(2S,3R,E)-2-Amino-4-icosene-1,3-diol
- Product Name
- (2S,3R,E)-2-Amino-4-icosene-1,3-diol
- CAS No.
- 6918-49-6
- Chemical Name
- (2S,3R,E)-2-Amino-4-icosene-1,3-diol
- Synonyms
- C20-Sphingosine;Eicosaphingenine;Eicosasphingenine;Gangliosphingosine;Sphingosine (d20:1);20-Carbon-sphingosine;D-erythro-Sphingosine C-20;(2S,3R,4E)-4-Icosasphingenine;D-erythro-Sphingosine (d20:1);D-erythro-sphingosine (C20 base)
- CBNumber
- CB82148391
- Molecular Formula
- C20H41NO2
- Formula Weight
- 327.55
- MOL File
- 6918-49-6.mol
(2S,3R,E)-2-Amino-4-icosene-1,3-diol Property
- storage temp.
- -20°C
- solubility
- DMF: 10 mg/ml; DMSO: 2 mg/ml; Ethanol: Miscible
- form
- A crystalline solid
- BRN
- 3547228
Safety
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 07768
- Product name
- (2S,3R,4E)-2-Amino-4-eicosene-1,3-diol
- Purity
- ≥98.0% (TLC)
- Packaging
- 10mg
- Price
- $203
- Updated
- 2023/06/20
- Product number
- 07768
- Product name
- (2S,3R,4E)-2-Amino-4-eicosene-1,3-diol
- Purity
- ≥98.0% (TLC)
- Packaging
- 50mg
- Price
- $867
- Updated
- 2023/01/07
- Product number
- 10007903
- Product name
- Sphingosine (d20:1)
- Purity
- ≥98%
- Packaging
- 500μg
- Price
- $33
- Updated
- 2024/03/01
- Product number
- 10007903
- Product name
- Sphingosine (d20:1)
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $62
- Updated
- 2024/03/01
- Product number
- 10007903
- Product name
- Sphingosine (d20:1)
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $176
- Updated
- 2024/03/01
(2S,3R,E)-2-Amino-4-icosene-1,3-diol Chemical Properties,Usage,Production
Description
Sphingosines are long-
Uses
Sphingosine (d20:1) has been used as a reference substance in liquid chromatography/tandem mass spectrometry analysis to quantitatively analyze sphingolipids with C20- long chain bases in human central nervous tissue.
Uses
D-erythro-Sphingosine-C20 is an antagonist in cell-signaling functions however it displays an opposite modulation of cathepsin D.
Definition
ChEBI: C20 sphingosine is a sphingoid that is the C20 analogue of sphingosine. It has a role as a mouse metabolite. It is a sphingoid and an aminodiol. It is a conjugate base of a C20 sphingosine(1+).
General Description
Sphingosine (d20:1), also known as icosasphingosine, is a synthetic sphingosine with 20 carbon long chain bases (LCB). It is directly produced by the sphingolipid de novo synthesis pathway and not by hydrolysis of complex sphingolipids. In higher animals, it is one of the most abundant sphingoid bases of gangliosides.
Biochem/physiol Actions
Sphingosine (d20:1) or C20-sphingosine acts as an intermediate in the synthesis of ceramides, which are vital components of mammalian epidermis. It may be involved in regulation of epidermal differentiation. C20 long chain bases-containing sphingolipids might exhibit detrimental effect on protein homeostasis and neural functions.
(2S,3R,E)-2-Amino-4-icosene-1,3-diol Preparation Products And Raw materials
Raw materials
Preparation Products
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