3-[(TERT-BUTYLDIMETHYLSILYL)OXY]-1-PROPANAL

Product Name: 3-[(TERT-BUTYLDIMETHYLSILYL)OXY]-1-PROPANAL
CAS No.: 89922-82-7
Chemical Name: 3-[(TERT-BUTYLDIMETHYLSILYL)OXY]-1-PROPANAL
Synonyms: DK948;DKSI074;DKFELEX0254;3-TBDMSO-propionaldehyde;3-tert-Butyldimethylsiloxy)propanal;3-tert-Butyldimethylsilyloxypropanal;3-(tert-Butyldimethylsiloxy)propionaldehyde;3-[(TERT-BUTYLDIMETHYLSILYL)OXY]-1-PROPANAL;3-t-Butyldimethylsilanyloxy Propionaldehyde;3-Tert-butyldiMethylsilyloxy)propionaldehyde
CBNumber: CB8218649
Molecular Formula: C9H20O2Si
Formula Weight: 188.34
MOL File: 89922-82-7.mol

More

Less

3-[(TERT-BUTYLDIMETHYLSILYL)OXY]-1-PROPANAL Property

Boiling point:: 95 °C(Press: 23 Torr)
Density: 0.892 g/mL at 25 °C
refractive index: n20/D1.431
Flash point:: 84℃
storage temp.: Inert atmosphere,Store in freezer, under -20°C
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Oil
color: Colourless to Pale Yellow
InChI: InChI=1S/C9H20O2Si/c1-9(2,3)12(4,5)11-8-6-7-10/h7H,6,8H2,1-5H3
InChIKey: WGWCJTNWUFFGFH-UHFFFAOYSA-N
SMILES: C(=O)CCO[Si](C(C)(C)C)(C)C

More

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: D6297
Product name: 3-[(tert-Butyldimethylsilyl)oxy]propanal
Purity: min. 95.0 %
Packaging: 1G
Price: $133
Updated: 2025/07/31

TCI Chemical

Product number: D6297
Product name: 3-[(tert-Butyldimethylsilyl)oxy]propanal
Purity: min. 95.0 %
Packaging: 5G
Price: $399
Updated: 2025/07/31

TRC

Product number: B691565
Product name: 3-[(tert-Butyldimethylsilyl)oxy]-1-propanal
Packaging: 25g
Price: $2190
Updated: 2021/12/16

TRC

Product number: B691565
Product name: 3-[(tert-Butyldimethylsilyl)oxy]-1-propanal
Packaging: 2g
Price: $190
Updated: 2021/12/16

TRC

Product number: B691565
Product name: 3-[(tert-Butyldimethylsilyl)oxy]-1-propanal
Packaging: 1g
Price: $100
Updated: 2021/12/16

More

Less

3-[(TERT-BUTYLDIMETHYLSILYL)OXY]-1-PROPANAL Chemical Properties,Usage,Production

Chemical Properties

Brown Oil

Uses

3-[(tert-Butyldimethylsilyl)oxy]-1-propanal is useful for preparing EGFR inhibitors for the treatment of cancer.

Preparation

3-(tert-Butyldimethylsilyloxy)propanol (1.90 g, 10 mmol) was dissolved in dichloromethane (20 mL), and Dess-Martin reagent (6.36 g, 15 mmol) was added under ice bath. After stirring at room temperature for 4 hours, saturated aqueous sodium bicarbonate solution was added to quench, and the mixture was diluted with dichloromethane (100 mL). The mixture was washed twice with saturated aqueous sodium bicarbonate solution and once with brine. The organic layer was dried over sodium sulfate, filtered and concentrated in vacuo. The mixture was purified by silica gel column chromatography to obtain 1.55 g of 3-[(tert-Butyldimethylsilyl)oxy]-1-propanal with a yield of 82%.

Chemical Reactivity

3-[(tert-Butyldimethylsilyl)oxy]-1-propanal is stable under normal conditions, it reacts with oxidizing agents.

3-[(TERT-BUTYLDIMETHYLSILYL)OXY]-1-PROPANAL Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

3-[(TERT-BUTYLDIMETHYLSILYL)OXY]-1-PROPANAL Suppliers

Canada 1 China 90 India 4 United States 8 Global 103

Zhuangming New Material Technology Jiangsu Co., Ltd.

Tel: 021-0513-86936896 18116363706
Email: sales@zhuangming.net
Country: China
ProdList: 583
Advantage: 58

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: (5)02557626880
Email: dt3@aikonchem.com
Country: China
ProdList: 15493
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15838
Advantage: 69

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14101
Advantage: 59

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11035
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Shanghai Topbiochem Technology Co., Ltd

Tel: +86-21-60341587
Fax: +86-21-61294319
Email: sales@topbiochem.com
Country: China
ProdList: 6175
Advantage: 58

Shanghai Gileader Advanced Material Technology Co.,Ltd

Tel: 18516111942
Email: 823898732@qq.com
Country: China
ProdList: 1328
Advantage: 56

More

Less

View Lastest Price from 3-[(TERT-BUTYLDIMETHYLSILYL)OXY]-1-PROPANAL manufacturers

Career Henan Chemical Co

Product: 3-[(TERT-BUTYLDIMETHYLSILYL)OXY]-1-PROPANAL 89922-82-7
Price: US $2.00/KG
Min. Order: 1KG
Purity: 98%MIN
Supply Ability: ASK
Release date: 2019-12-25

89922-82-7, 3-[(TERT-BUTYLDIMETHYLSILYL)OXY]-1-PROPANALRelated Search:

Side chain for imipenem 3,5-Di-O-(tert-butyldimethylsilyl)-2-deoxy-D-ribonolactone (3S,4R)-4-Acetoxy-3-[(R)-1-(tert-butyldimethylsilyloxy)ethyl]azetidin-2-one METHYL (R)-(+)-3-(TERT-BUTYLDIMETHYLSILYLOXY)-5-OXO-1-CYCLOPENTENE-1-HEPTANOATE 3-(tert-Butyldimethylsilyloxy)glutaric anhydride Propionaldehyde 3,6-DI-O-(TERT-BUTYLDIMETHYLSILYL)-D-GLUCAL FMOC-THR(TBDMS)-OH FMOC-SER(BSI)-OH (4S)-(-)-T-BUTYLDIMETHYLSILOXY-2-CYCLOPENTEN-1-ONE 3'-O-(T-BUTYLDIMETHYLSILYL)-5'-OXO-8,5'-CYCLO-2'-DEOXYADENOSINE N,N-DIBENZYL-O-(T-BUTYLDIMETHYLSILYL)-L-SERINE METHYL ESTER 4-TERT-BUTYLDIMETHYLSILYLOXY-2-DIETHYLAMINOMETHYL-2-CYCLOPENTENE-1-ONE METHYL (S)-(-)-4-BROMO-3-TERT-BUTYLDIMETHYLSILYLOXYBUTANOATE 4-O-ACETYL-3,6-DI-O-(TERT-BUTYLDIMETHYLSILYL)-D-GLUCAL (4R)-(+)-T-BUTYLDIMETHYLSILOXY-2-CYCLOPENTEN-1-ONE 2-METHYLIDENE-3-(R)-(3-(S)-T-BUTYLDIMETHYLSILOXY-OCT-1-(E)-ENE-1-YL)-4-(R)-T-BUTYL-DIMETHYLSILOXY-CYCLOPENTANONE 2-METHYLIDENE-3-(R)-(3-(S)-T-BUTYLDIMETHYLSILOXY-5-(S)-METHYL-NON-1-ENYL)-4-(R)-T-BUTYL-DIMETHYLSILOXY-CYCLOPENTANONE

3-[(TERT-BUTYLDIMETHYLSILYL)OXY]-1-PROPANAL

3-(TERT-BUTYL-DIMETHYL-SILANYLOXY)-PROPIONALDEHYDE

3-Tert-butyldiMethylsilyloxy)propionaldehyde

3-[[(1,1-DiMethylethyl)diMethylsilyl]oxy]propanal

Propanal,3-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-

3-(tert-Butyldimethylsiloxy)propionaldehyde

3-[Dimethyl(1,1-dimethylethyl)siloxy]propanal

3-TBDMSO-propionaldehyde

3-tert-Butyldimethylsiloxy)propanal

3-tert-Butyldimethylsilyloxypropanal

3-(tert-Butyldimethylsiloxy)propionaldehyde 96%

3-t-Butyldimethylsilanyloxy Propionaldehyde

DK948

DKFELEX0254

DKSI074

3-(<i>tert</i>-Butyldimethylsiloxy)propionaldehyde

89922-82-7

Miscellaneous Reagents