Amentoflavone 4',4''',7''-trimethyl ether

Product Name: Amentoflavone 4',4''',7''-trimethyl ether
CAS No.: 481-45-8
Chemical Name: Amentoflavone 4',4''',7''-trimethyl ether
Synonyms: Kayaflavone;Amentoflavone 4',4''',7''-trimethyl ether;Amentoflavone 4',4''',7''-trimethyl ether USP/EP/BP;8-[5-(5,7-Dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl]-5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one;2-(4-Methoxyphenyl)-5-hydroxy-7-methoxy-8-[2-methoxy-5-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)phenyl]-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 8-[5-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl]-5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-
CBNumber: CB82256692
Molecular Formula: C33H24O10
Formula Weight: 580.54
MOL File: 481-45-8.mol

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Amentoflavone 4',4''',7''-trimethyl ether Property

Melting point:: 314-315 °C (decomp)(Solv: methanol (67-56-1))
Boiling point:: 815.4±65.0 °C(Predicted)
Density: 1.445±0.06 g/cm3(Predicted)
pka: 6.00±0.40(Predicted)

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Hazard and Precautionary Statements (GHS)

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Amentoflavone 4',4''',7''-trimethyl ether Chemical Properties,Usage,Production

Uses

Kayaflavone is an amentoflavone type biflavonoid. Kayaflavone has an inhibitory activity against amyloid-β42 cytotoxicity in PC-12 cells with an EC50 value of 5.29 μΜ. Kayaflavone is promising for research of Alzheimer’s disease[1].

References

[1] Sasaki H, et al. Inhibitory activities of biflavonoids against amyloid-β peptide 42 cytotoxicity in PC-12 cells. Bioorg Med Chem Lett. 2015 Jul 15;25(14):2831-3. DOI:10.1016/j.bmcl.2015.04.106
[2] Sun CM, et al. Selective cytotoxicity of ginkgetin from Selaginella moellendorffii. J Nat Prod. 1997 Apr;60(4):382-4. DOI:10.1021/np960608e

Amentoflavone 4',4''',7''-trimethyl ether Preparation Products And Raw materials

Raw materials

Preparation Products

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Amentoflavone 4',4''',7''-trimethyl ether Suppliers

China 15 United States 1 Global 16

Sichuan Wei Keqi Biological Technology Co., Ltd.

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481-45-8, Amentoflavone 4',4''',7''-trimethyl etherRelated Search:

Xanthophyll AMENTOFLAVONE Amentoflavone

2-(4-Methoxyphenyl)-5-hydroxy-7-methoxy-8-[2-methoxy-5-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)phenyl]-4H-1-benzopyran-4-one

8-[5-(5,7-Dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl]-5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one

Amentoflavone 4',4''',7''-trimethyl ether

Kayaflavone

4H-1-Benzopyran-4-one, 8-[5-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl]-5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-

Amentoflavone 4',4''',7''-trimethyl ether USP/EP/BP

481-45-8