ChemicalBook > CAS DataBase List > 3-Hydroxy-2-naphthalenecarboxylic acid ethyl ester

3-Hydroxy-2-naphthalenecarboxylic acid ethyl ester

Product Name
3-Hydroxy-2-naphthalenecarboxylic acid ethyl ester
CAS No.
7163-25-9
Chemical Name
3-Hydroxy-2-naphthalenecarboxylic acid ethyl ester
Synonyms
3-Hydroxy-2-naphthoic acid ethyl ester;Ethyl 3-hydroxynaphthalene-2-carboxylate;3-Hydroxy-2-naphthalenecarboxylic acid ethyl ester;3-Hydroxy-naphthalene-2-carboxylic acid ethyl ester;2-Naphthalenecarboxylic acid, 3-hydroxy-, ethyl ester
CBNumber
CB82263942
Molecular Formula
C13H12O3
Formula Weight
216.23
MOL File
7163-25-9.mol
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3-Hydroxy-2-naphthalenecarboxylic acid ethyl ester Property

Melting point:
79.0 to 83.0 °C
Boiling point:
291°C(lit.)
Density 
1.1652 (rough estimate)
refractive index 
1.5090 (estimate)
solubility 
soluble in Toluene
form 
powder to crystal
pka
9.53±0.40(Predicted)
color 
White to Orange to Green
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Safety

HS Code 
2918290090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical
Product number
E1249
Product name
Ethyl 3-Hydroxy-2-naphthoate
Purity
>98.0%(GC)
Packaging
1g
Price
$57
Updated
2024/03/01
TCI Chemical
Product number
E1249
Product name
Ethyl 3-Hydroxy-2-naphthoate
Purity
>98.0%(GC)
Packaging
5g
Price
$284
Updated
2024/03/01
TRC
Product number
E940608
Product name
Ethyl 3-Hydroxy-2-naphthoate
Packaging
50mg
Price
$155
Updated
2021/12/16
Apolloscientific
Product number
OR27972
Product name
Ethyl 3-Hydroxy-2-naphthoate
Packaging
1g
Price
$206
Updated
2021/12/16
SynQuest Laboratories
Product number
2629-1-Z9
Product name
Ethyl 3-hydroxy-2-naphthoate
Packaging
1g
Price
$228
Updated
2021/12/16
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3-Hydroxy-2-naphthalenecarboxylic acid ethyl ester Chemical Properties,Usage,Production

Uses

3-Hydroxy-2-naphthalenecarboxylic acid ethyl ester can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

Synthesis


To a round bottom flask were added 5 g 3-hydroxy-2-naphthalic acidand 16 mL ethanol. The reaction mixture was refluxed for 6 h. After thecompletion of the reaction, the reaction mixture was cooled down to room temperature and washed with distilled water. The organic layerwas recovered and washed with saturated sodium bicarbonate followedby drying with anhydrous MgSO4. The MgSO4 was removed by filtrationand the filtrate was dried under reduced pressure. The resulted solid waspurified by silica chromatography with petroleum ether and ethyl acetate(10:1, v/v) as eluent to give the compound ethyl 3-hydroxy-2-naphthoate(4.1229 g, yield 70.60%).

3-Hydroxy-2-naphthalenecarboxylic acid ethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Hydroxy-2-naphthalenecarboxylic acid ethyl ester Suppliers

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7163-25-9, 3-Hydroxy-2-naphthalenecarboxylic acid ethyl esterRelated Search:


  • 3-Hydroxy-2-naphthalenecarboxylic acid ethyl ester
  • 3-Hydroxy-2-naphthoic acid ethyl ester
  • Ethyl 3-hydroxynaphthalene-2-carboxylate
  • 2-Naphthalenecarboxylic acid, 3-hydroxy-, ethyl ester
  • 3-Hydroxy-naphthalene-2-carboxylic acid ethyl ester
  • 7163-25-9