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CANDOXATRIL

Product Name
CANDOXATRIL
CAS No.
123122-55-4
Chemical Name
CANDOXATRIL
Synonyms
UK-79300;candoxatril;Candoxatril (UK 79300);Candoxatril [usan:inn:ban];4α-[[1-[(S)-2-(Indan-5-yloxycarbonyl)-3-(2-methoxyethoxy)propyl]cyclopentan-1-yl]carbonylamino]cyclohexane-1α-carboxylic acid;4α-[[1-[(S)-2-(Indan-5-yloxycarbonyl)-3-(2-methoxyethoxy)propyl]cyclopentan-1-yl]carbonylamino]cyclohexane-1α-carboxylic acid;cis-4-[[[1-[(2S)-3-[(2,3-Dihydro-1H-inden-5-yl)oxy]-2-[(2-Methoxyethoxy)Methyl]-3-oxopropyl]cyclopentyl]carbonyl]aMino]cyclohexanecarboxylic Acid;Cyclohexanecarboxylic acid, 4-[[[1-[(2S)-3-[(2,3-dihydro-1H-inden-5-yl)oxy]-2-[(2-methoxyethoxy)methyl]-3-oxopropyl]cyclopentyl]carbonyl]amino]-,cis-
CBNumber
CB82280992
Molecular Formula
C29H41NO7
Formula Weight
515.63834
MOL File
123122-55-4.mol
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CANDOXATRIL Property

Melting point:
107-109°
alpha 
D -5.8° (c = 1 in methanol)
Boiling point:
718.4±60.0 °C(Predicted)
Density 
1.21±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
pka
4.84±0.25(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
C175200
Product name
Candoxatril
Packaging
10mg
Price
$7425
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0007547
Product name
CANDOXATRIL
Purity
95.00%
Packaging
10MG
Price
$8373.75
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0007547
Product name
CANDOXATRIL
Purity
95.00%
Packaging
1MG
Price
$2769.9
Updated
2021/12/16
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CANDOXATRIL Chemical Properties,Usage,Production

Uses

Neutral endopeptidase inhibitor. Used in treatment of congestive heart failure.

Uses

Neutral endopeptidase inhibitor. Candoxatril is used in treatment of congestive heart failure.

Definition

ChEBI: The 2,3-dihydro-1H-inden-5-yl ester of the active enantiomer of candoxatrilat. Candoxatril is an orally active prodrug of candoxatrilat, a potent neutral endopeptidase (NEP, neprilysin) inhibitor used in the treatment of chronic heart fa lure.

CANDOXATRIL Preparation Products And Raw materials

Raw materials

Preparation Products

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123122-55-4, CANDOXATRILRelated Search:


  • 4α-[[1-[(S)-2-(Indan-5-yloxycarbonyl)-3-(2-methoxyethoxy)propyl]cyclopentan-1-yl]carbonylamino]cyclohexane-1α-carboxylic acid
  • UK-79300
  • Candoxatril [usan:inn:ban]
  • Candoxatril (UK 79300)
  • Cyclohexanecarboxylic acid, 4-[[[1-[(2S)-3-[(2,3-dihydro-1H-inden-5-yl)oxy]-2-[(2-methoxyethoxy)methyl]-3-oxopropyl]cyclopentyl]carbonyl]amino]-,cis-
  • candoxatril
  • cis-4-[[[1-[(2S)-3-[(2,3-Dihydro-1H-inden-5-yl)oxy]-2-[(2-Methoxyethoxy)Methyl]-3-oxopropyl]cyclopentyl]carbonyl]aMino]cyclohexanecarboxylic Acid
  • 4α-[[1-[(S)-2-(Indan-5-yloxycarbonyl)-3-(2-methoxyethoxy)propyl]cyclopentan-1-yl]carbonylamino]cyclohexane-1α-carboxylic acid
  • 123122-55-4
  • C29H41NO7
  • Aromatics
  • Chiral Reagents
  • Pharmaceuticals
  • Inhibitors
  • Intermediates & Fine Chemicals