FMRF AMIDE

Product Name: FMRF AMIDE
CAS No.: 152165-14-5
Chemical Name: FMRF AMIDE
Synonyms: FMRF-NH2;FMRF AMIDE;PHE-MET-ARG-PHE-NH2;PHE-MET-ARG-PHE AMIDE;H-PHE-MET-ARG-PHE-NH2;FMRFAMIDE ACETATE SALT;FMRF-AMIDE 1 1/2ACOH 2H2O;H-PHE-MET-ARG-PHE-NH2 ACOH;PHE-MET-ARG-PHE-NH2: FMRF-NH2;H-Phe-Met-Arg-Phe-NH2 acetate
CBNumber: CB8231121
Molecular Formula: C29H42N8O4S
Formula Weight: 598.76
MOL File: 152165-14-5.mol

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FMRF AMIDE Property

storage temp.: −20°C
Sequence: Phe-Met-Arg-Phe-NH2

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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FMRF AMIDE Chemical Properties,Usage,Production

Uses

Phe-Met-Arg-Phe, amide acetate dose dependently (ED50=23 nM) activates a K+ current in the peptidergic caudodorsal neurons[1].

in vivo

Phe-Met-Arg-Phe, amide (FMRFamide) acetate stimulates growth hormone secretion in conscious OVX rats. The presence of Phe-Met-Arg-Phe, amide-like immunoreactivity in neuronal elements in the hypothalamus suggested a role for this in the hypothalamic control of the anterior pituitary function. The injection of 200 ng (313.8 pM) of FMRFamide (in 2 uL) produces a significantly increased plasma GH 15 min after injection. The GH-increasing effect of 400-800 ng (627-1255 pM) of FMRFamide is already developed after 5 min and lasted up to 30 min^[3].

References

[1] Kits KS, et al. Phe-Met-Arg-Phe-amide activates a novel voltage-dependent K+ current through a lipoxygenasepathway in molluscan neurones. J Gen Physiol. 1997 Nov;110(5):611-28. DOI:10.1085/jgp.110.5.611
[2] Sorenson RL, et al. Phe-met-arg-phe-amide (FMRF-NH2) inhibits insulin and somatostatin secretion and anti-FMRF-NH2 sera detects pancreatic polypeptide cells in the rat islet. Peptides. 1984 Jul-Aug;5(4):777-82. DOI:10.1016/0196-9781(84)90021-4
[3] Ottlecz A, et al. Phe-Met-Arg-Phe-amide (FMRFamide) stimulated growth hormone secretion in conscious OVX rats. Neuropeptides. 1987 Feb-Mar;9(2):161-7. DOI:10.1016/0143-4179(87)90054-0

FMRF AMIDE Preparation Products And Raw materials

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FMRF AMIDE Suppliers

China 80 United Kingdom 1 United States 4 Global 85

GL Biochem (Shanghai) Ltd

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Nanjing Peptide Biotech Ltd.

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Hangzhou Peptidego Biotech Co.,Ltd.

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152165-14-5, FMRF AMIDERelated Search:

FMRF-AMIDE LIKE PEPTIDE 1 (LOBSTER),FMRF AMIDE-LIKE PEPTIDE I, LOBSTER FMRF amide (Nle-Arg-Phe-NH2) FMRF amide (Phe-Met-Arg-Phe) FMRF amide-like Peptide II (lobster) (Thr-Asn-Arg-Asn-Phe-Leu-Arg-Phe-NH2) FMRF amide (Tyr-Phe-Met-Arg-Phe-NH2) FMRF amide (Ac-Phe-Nle-Arg-Phe-NH2) FMRF amide (Phe-Met-Arg-Phe-NH2) (Molluscan Cardioexcitatory Neuropeptide) FMRF amide (AF-2) (Lys-His-Glu-Tyr-Leu-Arg-Phe-NH2) FMRF amide (AF-1) (Lys-Asn-Glu-Phe-Ile-Arg-Phe-NH2) FMRF amide (Phe-Leu-Arg-Arg) H-TYR-PHE-MET-ARG-PHE-NH2 [D-MET2]-FMRF-AMIDE FMRF amide (Trp-Nle-Arg-Phe-NH2) FMRF amide (Met-Arg-Phe) H-TYR-GLY-GLY-PHE-MET-ARG-PHE-NH2 TYR-MET-ARG-PHE-NH2 FMRF AMIDE FMRF amide [D-Phe4] (Phe-Met-Arg-D-Phe-NH2)

PHE-MET-ARG-PHE AMIDE

PHE-MET-ARG-PHE-NH2

PHE-MET-ARG-PHE-NH2 1/2ACOH 2H2O

MOLLUSCAN CARDIOEXCITATORY PEPTIDE

MOLLUSCAN CARDIOEXCITATORY NEUROPEPTIDE

MOLLUSCAN CARDIOEXCITATORY NEUROPEPTIDE 1 1/2 ACOH 2H2O

MOLLUSCAN CARDIOEXCITATORY NEUROPEPTIDE ACETATE SALT

H-PHE-MET-ARG-PHE-NH2

H-PHE-MET-ARG-PHE-NH2 ACETATE SALT

H-PHE-MET-ARG-PHE-NH2 ACOH

FMRF-NH2

FMRF AMIDE MOLLUSCAN CARDIOEXCITATORY PEPTIDE

FMRF AMIDE

FMRF-AMIDE 1 1/2ACOH 2H2O

FMRFAMIDE ACETATE SALT

PHE-MET-ARG-PHE-NH2: FMRF-NH2

H-Phe-Met-Arg-Phe-NH2 acetate

152165-14-5

C31H46N8O6S

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