6-BROMO-2-PYRIDINEMETHANAMINE

Application

Product Name: 6-BROMO-2-PYRIDINEMETHANAMINE
CAS No.: 188637-63-0
Chemical Name: 6-BROMO-2-PYRIDINEMETHANAMINE
Synonyms: (6-BroMopyridin-2-yl)MethanaMine;(6-Bromopyridin-2-yl);6-Bromo-2-pyridinethylamine;6-Bromo-2-pyridinemethanamin;6-BROMO-2-PYRIDINEMETHANAMINE;6-bromo-2-pyridinenethanamine;6-BROMO-2-PYRIDINEMETHANEAMINE;2-(Aminomethyl)-6-bromopyridine;2-Pyridinemethanamine, 6-bromo-;1-(6-bromopyridin-2-yl)methanamine
CBNumber: CB8235477
Molecular Formula: C6H7BrN2
Formula Weight: 187.04
MOL File: 188637-63-0.mol

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6-BROMO-2-PYRIDINEMETHANAMINE Property

Boiling point:: 266.9±25.0 °C(Predicted)
Density: 1.574±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 8.42±0.39(Predicted)
form: liquid
color: Colourless to light yellow
InChI: InChI=1S/C6H7BrN2/c7-6-3-1-2-5(4-8)9-6/h1-3H,4,8H2
InChIKey: WNUXZPQIGBMHSI-UHFFFAOYSA-N
SMILES: C1(CN)=NC(Br)=CC=C1

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Safety

Hazard Codes: T
Risk Statements: 25
Safety Statements: 45
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: B428093
Product name: (6-bromopyridin-2-yl)methanamine
Packaging: 500mg
Price: $220
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB142299
Product name: (6-Bromopyridin-2-yl)methanamine
Packaging: 500mg
Price: $250
Updated: 2021/12/16

AK Scientific

Product number: X7041
Product name: 6-Bromo-2-aminomethylpyridine
Packaging: 250mg
Price: $266
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB142299
Product name: (6-Bromopyridin-2-yl)methanamine
Packaging: 1g
Price: $390
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 38076
Product name: (6-Bromopyridin-2-yl)methanamine
Purity: 95+%
Packaging: 250mg
Price: $406
Updated: 2021/12/16

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6-BROMO-2-PYRIDINEMETHANAMINE Chemical Properties,Usage,Production

Application

The molecular structure of 6-bromo-2-pyridinemethylamine contains a bromine atom at position 6 and a methylamine functional group at position 2. Both positions are relatively easy sites for functional group transformation. The bromine atom in this substance can participate in a variety of coupling reactions, making it widely applicable in organic synthesis.

Synthesis

521917-57-7

188637-63-0

The general procedure for the synthesis of 6-bromo-2-pyridinemethanamine from the compound (CAS: 521917-57-7) is as follows: A214.1 (214.1 g) was suspended in anhydrous ethanol (420 mL) and heated at 70 °C for 30 min. To this non-homogeneous solution was slowly added hydrazine monohydrate. The reaction mixture became homogeneous within 1 min. Heating of the reaction mixture was continued for 3 hours, during which time the mixture gradually solidified to a white solid. Subsequently, 100 mL of ethanol was added to the reaction system and the mixture was filtered. The precipitate was washed well with ethanol and the filtrate was partially concentrated. The solid was collected by vacuum filtration. The filtrate was further concentrated to dryness and then ground with methanol. The product A214.2 was collected by vacuum filtration to give 14.3 g (93% yield) of white solid. The compound was analyzed by HPLC under the following conditions: retention time = 0.395 min (column: Chromolith SpeedROD 4.6 x 50 mm; run time: 4 min; mobile phase A: 10% methanol, 90% water with 0.1% trifluoroacetic acid; mobile phase B: 90% methanol, 10% water with 0.1% trifluoroacetic acid).LC/MS analysis showed [M+1]+ peaks of 187.12 and 189.12.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2011, vol. 21, # 23, p. 7006 - 7012
[2] Patent: WO2006/122137, 2006, A1. Location in patent: Page/Page column 158
[3] Organic Letters, 2013, vol. 15, # 9, p. 2290 - 2293
[4] Journal of Organic Chemistry, 2017, vol. 82, # 10, p. 5046 - 5067
[5] Patent: WO2006/122137, 2006, A1. Location in patent: Page/Page column 158

6-BROMO-2-PYRIDINEMETHANAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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6-BROMO-2-PYRIDINEMETHANAMINE Suppliers

China 103 India 1 United Kingdom 2 United States 13 Global 119

Andxi Pharm Co., Ltd.

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View Lastest Price from 6-BROMO-2-PYRIDINEMETHANAMINE manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: (6-Bromopyridin-2-yl)methanamine 188637-63-0
Price: US $1.10-9.90/kg
Min. Order: 1kg
Purity: 99%min
Supply Ability: 100kg
Release date: 2025-08-14

Zhuozhou Wenxi import and Export Co., Ltd

Product: 6-BROMO-2-PYRIDINEMETHANAMINE 188637-63-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 6-BROMO-2-PYRIDINEMETHANAMINE 188637-63-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

188637-63-0, 6-BROMO-2-PYRIDINEMETHANAMINERelated Search:

5-BROMO-3-PYRIDINEMETHANAMINE 6-BROMO-2-PYRIDINEMETHANAMINE, HYDROCHLORIDE 6-Bromopyridine-2-carboxamide 98% Sodium 2-diazo-1-naphthol-5-sulfonate 6-BROMO-N-METHOXY-N-METHYLPYRIDINE-2-CARBOXAMIDE [1-(6-BROMOPYRIDIN-2-YL)-2,2,2-TRIFLUOROETHYL]AMINE 6-BROMO-2-PYRIDINEMETHANAMINE 6-BROMO-N-METHYLPYRID-2-YLMETHYLAMINE 4-(TERT-BUTOXYCARBONYLAMINO)-1-[(6-BROMOPYRIDIN-2-YL)METHYL]PIPERIDINE RARECHEM AL BZ 0877 SALOR-INT L481343-1EA [[(6-BROMO)-2-PYRIDINYL]METHYL]-CARBAMIC ACID, 1,1-DIMETHYLETHYL ESTER CHEMPACIFIC 38207

6-bromo-2-pyridinenethanamine

6-BROMO-2-PYRIDINEMETHANAMINE

6-BROMO-2-PYRIDINEMETHANEAMINE

6-Bromo-2-pyridinemethanamin

6-Bromo-2-pyridinethylamine

1-(6-bromopyridin-2-yl)methanamine

2-Pyridinemethanamine, 6-bromo-

(6-BroMopyridin-2-yl)MethanaMine

C-(6-Bromo-pyridin-2-yl)-methylamine

(6-Bromopyridin-2-yl)

2-(Aminomethyl)-6-bromopyridine

(6-Bromopyridin-2-yl)methanamine - [B90246]

188637-63-0

Pyridine series