2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA

Physical Form

Product Name: 2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA
CAS No.: 71432-55-8
Chemical Name: 2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA
Synonyms: 2-TERT-BUTYL-1;3-DIISOPROPYLISOUREA;2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA;O-tert-Butyl-N,N'-diisopropylisourea;O-tert-Butyl-N,N'-diisopropylisourea;O-tert-Butyl-N,N'-diisopropylisourea >tert-Butyl N,N'-diisopropylcarbamimidate;tert-Butyl N,N'-diisopropylimidocarbamate;N,N'-diisopropyltert-butoxymethanimidamide;tert-butyl N,N'-bis(1-methylethyl)imidocarbamate
CBNumber: CB8239657
Molecular Formula: C11H24N2O
Formula Weight: 200.32
MOL File: 71432-55-8.mol

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2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA Property

Boiling point:: 61°C/10mmHg(lit.)
Density: 0.89±0.1 g/cm3(Predicted)
refractive index: 1.4240-1.4280
storage temp.: Keep in dark place,Inert atmosphere,2-8°C
pka: 9.54±0.50(Predicted)
form: clear liquid
color: Colorless to Almost colorless
InChI: InChI=1S/C11H24N2O/c1-8(2)12-10(13-9(3)4)14-11(5,6)7/h8-9H,1-7H3,(H,12,13)
InChIKey: FESDUDPSRMWIDL-UHFFFAOYSA-N
SMILES: C(=NC(C)C)(OC(C)(C)C)NC(C)C

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Safety

HS Code: 2925290090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: B4178
Product name: O-tert-Butyl-N,N'-diisopropylisourea
Purity: >98.0%(T)
Packaging: 1g
Price: $75
Updated: 2025/07/31

TCI Chemical

Product number: B4178
Product name: O-tert-Butyl-N,N'-diisopropylisourea
Purity: >98.0%(T)
Packaging: 5g
Price: $255
Updated: 2025/07/31

TRC

Product number: B692565
Product name: 2-tert-Butyl-1,3-diisopropylisourea
Packaging: 2.5g
Price: $160
Updated: 2021/12/16

TRC

Product number: B692565
Product name: 2-tert-Butyl-1,3-diisopropylisourea
Packaging: 25g
Price: $1260
Updated: 2021/12/16

Chem-Impex

Product number: 24355
Product name: 2-tert-Butyl-1,3-diisopropylisourea,96%(Assay)
Purity: 96%(Assay)
Packaging: 1G
Price: $39.2
Updated: 2021/12/16

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2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA Chemical Properties,Usage,Production

Physical Form

liquid

Uses

2-tert-Butyl-1,3-diisopropylisourea is a useful synthetic intermediate in the synthesis of 5-Oxo Atorvastatin tert-Butyl Ester (O847160) which is a Boc-protected derivative of Atorvastatin. 2-tert-Butyl-1,3-diisopropylisourea is also used as a reagent in the total synthesis of Citrafungin A which is an antifungal natural product.

Synthesis

693-13-0

75-65-0

71432-55-8

GENERAL STEPS: CuCl (63.4 mg, 0.64 mmol, 1 mol%) was added to a solution of N,N'-diisopropylcarbodiimide (10.0 mL, 63.9 mmol, 1.0 equiv) in tert-butanol (6.97 mL, 73.5 mmol, 1.15 equiv). The reaction mixture was stirred at room temperature for 14 hours. After completion of the reaction, purification was carried out by distillation under reduced pressure (80°C, 25 mmHg). 2-tert-butyl-1,3-diisopropylisourea was obtained as a colorless oil (10.4 g, 51.9 mmol, 81% yield). The product was characterized by 1H NMR (300 MHz, CDCl3): δ 3.80-3.58 (1H, m, CH), 3.31-2.97 (1H, m, CH), 1.44 (9H, s, tBu), 1.19-1.01 (12H, m, Me2×2).

References

[1] Organic Letters, 2005, vol. 7, # 13, p. 2615 - 2618
[2] Chemistry - A European Journal, 2007, vol. 13, # 30, p. 8543 - 8563
[3] Beilstein Journal of Organic Chemistry, 2011, vol. 7, p. 1486 - 1493
[4] Journal of Medicinal Chemistry, 2015, vol. 58, # 10, p. 4204 - 4219
[5] Patent: EP2952517, 2015, A1. Location in patent: Paragraph 0217

2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA Preparation Products And Raw materials

Raw materials

Preparation Products

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2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA Suppliers

Americas 1 Belgium 1 Canada 1 CHINA 118 Europe 1 France 1 Germany 4 India 7 Japan 2 United Kingdom 3 United States 25 Global 164

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View Lastest Price from 2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA manufacturers

Career Henan Chemical Co

Product: 2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA 71432-55-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1000KGS
Release date: 2019-12-25

71432-55-8, 2-TERT-BUTYL-1,3-DIISOPROPYLISOUREARelated Search:

NITRIC OXIDE 4-AMINOPHENYLBORONIC ACID HYDROCHLORIDE N,N-DIMETHYLFORMAMIDE DINEOPENTYL ACETAL O-METHYL-N,N'-DIISOPROPYLISOUREA 2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA

2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA

CarbaMiMidic acid, N,N'-bis(1-Methylethyl)-, 1,1-diMethylethyl ester

tert-Butyl N,N'-diisopropylimidocarbamate

tert-butyl N,N'-bis(1-methylethyl)imidocarbamate

O-tert-Butyl-N,N'-diisopropylisourea &gt

3-DIISOPROPYLISOUREA

2-TERT-BUTYL-1

N,N'-bis(propan-2-yl)(tert-butoxy)methanimidamide

1,1-Dimethylethyl N,N'-bis(1-methylethyl)carbamimidate

N,N'-diisopropyltert-butoxymethanimidamide

1-[(2-methylprop-2-yl)oxy]-N-(prop-2-yl)-1-(prop-2-ylamino)methanimine

O-tert-Butyl-N,N'-diisopropylisourea

tert-Butyl N,N'-diisopropylcarbamimidate

2-Methyl-2-propanyl N,N'-diisopropylcarbamimidate

O-tert-Butyl-N,N'-diisopropylisourea

71432-55-8

C11H24N2O