ChemicalBook > CAS DataBase List > 2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA

2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA

Physical Form

Product Name: 2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA
CAS No.: 71432-55-8
Chemical Name: 2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA
Synonyms: 2-TERT-BUTYL-1;3-DIISOPROPYLISOUREA;2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA;O-tert-Butyl-N,N'-diisopropylisourea;O-tert-Butyl-N,N'-diisopropylisourea;O-tert-Butyl-N,N'-diisopropylisourea >tert-Butyl N,N'-diisopropylcarbamimidate;tert-Butyl N,N'-diisopropylimidocarbamate;N,N'-diisopropyltert-butoxymethanimidamide;tert-butyl N,N'-bis(1-methylethyl)imidocarbamate
CBNumber: CB8239657
Molecular Formula: C11H24N2O
Formula Weight: 200.32
MOL File: 71432-55-8.mol

Less

2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA Property

Boiling point:: 61°C/10mmHg(lit.)
Density: 0.89±0.1 g/cm3(Predicted)
refractive index: 1.4240-1.4280
storage temp.: Keep in dark place,Inert atmosphere,2-8°C
pka: 9.54±0.50(Predicted)
form: clear liquid
color: Colorless to Almost colorless
InChI: InChI=1S/C11H24N2O/c1-8(2)12-10(13-9(3)4)14-11(5,6)7/h8-9H,1-7H3,(H,12,13)
InChIKey: FESDUDPSRMWIDL-UHFFFAOYSA-N
SMILES: C(=NC(C)C)(OC(C)(C)C)NC(C)C

Less

Safety

HS Code: 2925290090

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: B4178
Product name: O-tert-Butyl-N,N'-diisopropylisourea
Purity: >98.0%(T)
Packaging: 1g
Price: $75
Updated: 2025/07/31

TCI Chemical

Product number: B4178
Product name: O-tert-Butyl-N,N'-diisopropylisourea
Purity: >98.0%(T)
Packaging: 5g
Price: $255
Updated: 2025/07/31

TRC

Product number: B692565
Product name: 2-tert-Butyl-1,3-diisopropylisourea
Packaging: 2.5g
Price: $160
Updated: 2021/12/16

TRC

Product number: B692565
Product name: 2-tert-Butyl-1,3-diisopropylisourea
Packaging: 25g
Price: $1260
Updated: 2021/12/16

Chem-Impex

Product number: 24355
Product name: 2-tert-Butyl-1,3-diisopropylisourea,96%(Assay)
Purity: 96%(Assay)
Packaging: 1G
Price: $39.2
Updated: 2021/12/16

Less

2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA Chemical Properties,Usage,Production

Physical Form

liquid

Uses

2-tert-Butyl-1,3-diisopropylisourea is a useful synthetic intermediate in the synthesis of 5-Oxo Atorvastatin tert-Butyl Ester (O847160) which is a Boc-protected derivative of Atorvastatin. 2-tert-Butyl-1,3-diisopropylisourea is also used as a reagent in the total synthesis of Citrafungin A which is an antifungal natural product.

Synthesis

693-13-0

75-65-0

71432-55-8

GENERAL STEPS: CuCl (63.4 mg, 0.64 mmol, 1 mol%) was added to a solution of N,N'-diisopropylcarbodiimide (10.0 mL, 63.9 mmol, 1.0 equiv) in tert-butanol (6.97 mL, 73.5 mmol, 1.15 equiv). The reaction mixture was stirred at room temperature for 14 hours. After completion of the reaction, purification was carried out by distillation under reduced pressure (80°C, 25 mmHg). 2-tert-butyl-1,3-diisopropylisourea was obtained as a colorless oil (10.4 g, 51.9 mmol, 81% yield). The product was characterized by 1H NMR (300 MHz, CDCl3): δ 3.80-3.58 (1H, m, CH), 3.31-2.97 (1H, m, CH), 1.44 (9H, s, tBu), 1.19-1.01 (12H, m, Me2×2).

References

[1] Organic Letters, 2005, vol. 7, # 13, p. 2615 - 2618
[2] Chemistry - A European Journal, 2007, vol. 13, # 30, p. 8543 - 8563
[3] Beilstein Journal of Organic Chemistry, 2011, vol. 7, p. 1486 - 1493
[4] Journal of Medicinal Chemistry, 2015, vol. 58, # 10, p. 4204 - 4219
[5] Patent: EP2952517, 2015, A1. Location in patent: Paragraph 0217

2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA Preparation Products And Raw materials

Raw materials

Preparation Products

Less

2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA Suppliers

Americas 1 Belgium 1 Canada 1 CHINA 118 Europe 1 France 1 Germany 4 India 7 Japan 2 United Kingdom 3 United States 25 Global 164

Yantai Boyun Biological Technology Co. Ltd

Tel: 13793517650; 13793517650
Email: 2767277144@qq.com
Country: China
ProdList: 2856
Advantage: 58

Suzhou Victorypharm Co.,Ltd.

Tel: 512-68242903 13916956214
Email: sales@victory-pharm.com
Country: China
ProdList: 1551
Advantage: 58

Yangzhou modier Electronic Materials Co., Ltd

Tel: 0514-82098883; 13761402923
Email: market@modeltemol.com
Country: China
ProdList: 996
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66113011 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19913
Advantage: 55

Shaoyuan Technology (Shanghai) Co., Ltd.

Tel: 021-50795510 4000665055
Email: sy-c6@accelachem.com
Country: China
ProdList: 10000
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12000
Advantage: 60

shanghai science Bio-Pharmceutical.co,ltd.

Tel: 021-021-57872719 13761402923
Fax: 02157872719
Email: 245662540@qq.com
Country: China
ProdList: 310
Advantage: 60

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 16077
Advantage: 64

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 18270980682
Fax: 021 51613951
Email: mlcheng@sunwaypharm.cn
Country: China
ProdList: 8669
Advantage: 57

Hunan Hui Bai Shi Biotechnology Co., Ltd.

Tel: 0731-85526065 13308475853
Email: ivy@hnhbsj.com
Country: China
ProdList: 7247
Advantage: 62

Hangzhou Sage Chemical Co., Ltd.

Tel: +86057186818502 13588463833
Fax: Pls mail us for more information!
Email: info@sagechem.com
Country: China
ProdList: 10266
Advantage: 58

Shanghai Topbiochem Technology Co., Ltd

Tel: 021-58170097
Email: info@topbiochem.com
Country: China
ProdList: 9510
Advantage: 58

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 22514
Advantage: 55

Suzhou Sino Rare Chemical Co., Ltd.

Tel: 0512-62857507
Fax: +86-512-62857507
Email: sales@sinorarechem.com
Country: China
ProdList: 998
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Suzhou Laing Biological Technology Co., LTD

Tel: 0512-62968256 18550502935
Fax: 0512-62968256
Email: export@laingbiotec.com
Country: China
ProdList: 981
Advantage: 58

Shanghai Xingui Biotechnology Co., Ltd.

Tel: 15121041756
Email: xingui2022@126.com
Country: China
ProdList: 9986
Advantage: 58

Hangzhou J&H Chemical Co., Ltd.

Tel: 0571-87396432
Fax: 0571-87396431
Email: sales@jhechem.com
Country: China
ProdList: 14912
Advantage: 59

Shanghai HuanChuan Industry Co.,Ltd.

Tel: 021-61478794
Fax: 021-61478794
Email: sales@hcshhai.com
Country: China
ProdList: 9793
Advantage: 50

Cool Pharm, Ltd

Tel: 021-60455363 18019463053
Fax: 50966098
Email: sales@coolpharm.com
Country: China
ProdList: 12346
Advantage: 58

Quzhou Rundong Chemical (Technology) Co.

Tel: 0570-8789886 18892685668
Fax: 0570-8789985
Email: info@rundongchemical.com
Country: China
ProdList: 4053
Advantage: 60

Struchem Co., Ltd.

Tel: 0512-63009836 18994340901
Fax: 0512-63006936
Email: helen@struchem.com
Country: China
ProdList: 3981
Advantage: 60

Shanghai Synchem Pharma Co., ltd

Tel: 21-619849051-1 18521059765
Email: synchempharma@aliyun.com
Country: China
ProdList: 6468
Advantage: 55

ShangHai Siyan Biological Technology Co., Ltd.

Tel: 021-50908862，442785678，326799392 18721037013
Fax: 021-50908862
Email: siyansales@126.com
Country: China
ProdList: 9627
Advantage: 58

Shanghai Qiao Chemical Science Co., Ltd

Tel: 021-58892003
Email: info@qiaochem.com
Country: China
ProdList: 6059
Advantage: 65

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Shanghai Changyan Chem & Tech Co., Ltd.

Tel: 021-20242659 18930833303
Fax: +86 (21) 2024-2659
Email: Sales@changyanchem.cn
Country: China
ProdList: 5001
Advantage: 55

parabiochem

Tel: 025-83453382-8005
Fax: 025-83453382
Email: sale@parabiochem.com
Country: China
ProdList: 9595
Advantage: 55

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Shanghai Kangman Biological Technology Co., Ltd.

Tel: 18800375331
Fax: 021-50908862
Email: kangmansales@163.com
Country: China
ProdList: 7570
Advantage: 55

Amatek Scientific Co. Ltd.

Tel: 0512-56316828
Fax: 0512-56316826
Email: info@amateksci.com
Country: China
ProdList: 28785
Advantage: 58

Jiaxing Deyi Chemical Co., Ltd.

Tel: 86-0573-85866609 13325730825
Fax: 0573-85866609
Email: 945717149@qq.com
Country: China
ProdList: 8595
Advantage: 58

Conier Chem & Pharma Limited

Tel: 13368167990
Email: sales@conier.com
Country: China
ProdList: 185
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 400821072
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 25000
Advantage: 58

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400-6387771-6039 18920764717
Email: sales@heowns.com
Country: China
ProdList: 23771
Advantage: 60

Jinan Kabotang Biological Technology Co.,Ltd.

Tel: 0531-61320525 15866703830
Email: figo.gao@foxmail.com
Country: China
ProdList: 5177
Advantage: 58

Shanghai SPAR pharmaceutical technology co., LTD

Tel: 021-000000
Email: admin@jingshipharmatech.com
Country: China
ProdList: 9853
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Shanghai Han-Xiang Chemical Co., Ltd.

Tel: 15971444841
Fax: 18327183813
Email: amber@biochempartner.com
Country: China
ProdList: 3061
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57422
Advantage: 58

Henan Alpha Chemical Co., Ltd.

Tel: 0371-55055611 18137792234
Fax: QQ：3002694073
Email: 3002694073@qq.com
Country: China
ProdList: 9987
Advantage: 58

Suzhou Victorypharm Co.,Ltd.

Tel: +86-13916956214
Email: sales@victory-pharm.com
Country: China
ProdList: 1299
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418684 +8618949823763
Fax: 0086-551-65418684
Email: sales@tnjchem.com
Country: China
ProdList: 25356
Advantage: 58

Yangzhou Model Electronic Materials Co., Ltd.

Tel: +8613761402923
Email: sales@modeltemol.com
Country: CHINA
ProdList: 571
Advantage: 58

Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30229
Advantage: 58

Guangdong Wengjiang Chemical Reagent Co., Ltd.

Tel: 0751-2886766 13927870850
Fax: 0751-2886756
Email: 3001267247@qq.com
Country: China
ProdList: 9941
Advantage: 58

Shandong chuangyingchemical Co., Ltd.

Tel: 18853181302
Email: sale@chuangyingchem.com
Country: CHINA
ProdList: 5906
Advantage: 58

Less

View Lastest Price from 2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA manufacturers

Career Henan Chemical Co

Product: 2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA 71432-55-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1000KGS
Release date: 2019-12-25

71432-55-8, 2-TERT-BUTYL-1,3-DIISOPROPYLISOUREARelated Search:

NITRIC OXIDE 4-AMINOPHENYLBORONIC ACID HYDROCHLORIDE N,N-DIMETHYLFORMAMIDE DINEOPENTYL ACETAL O-METHYL-N,N'-DIISOPROPYLISOUREA 2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA

2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA

CarbaMiMidic acid, N,N'-bis(1-Methylethyl)-, 1,1-diMethylethyl ester

tert-Butyl N,N'-diisopropylimidocarbamate

tert-butyl N,N'-bis(1-methylethyl)imidocarbamate

O-tert-Butyl-N,N'-diisopropylisourea &gt

3-DIISOPROPYLISOUREA

2-TERT-BUTYL-1

N,N'-bis(propan-2-yl)(tert-butoxy)methanimidamide

1,1-Dimethylethyl N,N'-bis(1-methylethyl)carbamimidate

N,N'-diisopropyltert-butoxymethanimidamide

1-[(2-methylprop-2-yl)oxy]-N-(prop-2-yl)-1-(prop-2-ylamino)methanimine

O-tert-Butyl-N,N'-diisopropylisourea

tert-Butyl N,N'-diisopropylcarbamimidate

2-Methyl-2-propanyl N,N'-diisopropylcarbamimidate

O-tert-Butyl-N,N'-diisopropylisourea

71432-55-8

C11H24N2O