1-IODO-3,4-METHYLENEDIOXYBENZENE
- Product Name
- 1-IODO-3,4-METHYLENEDIOXYBENZENE
- CAS No.
- 5876-51-7
- Chemical Name
- 1-IODO-3,4-METHYLENEDIOXYBENZENE
- Synonyms
- 5-Iodobenzo[d][1,3]dioxole;5-Iodine Pepper Ring;5-IODO-1,3-BENZODIOXOLE;1,3-Benzodioxole, 5-iodo-;2-iodo-5-nitrobenzenamine;5-iodo-2H-1,3-benzodioxole;3,4-Methylenedioxyiodobenzene;5-Iodo-2-methylbenzotrifluoride;1-IODO-3,4-METHYLENEDIOXYBENZENE;4-Iodo-1,2-(Methylenedioxy)benzene
- CBNumber
- CB8241649
- Molecular Formula
- C7H5IO2
- Formula Weight
- 248.02
- MOL File
- 5876-51-7.mol
1-IODO-3,4-METHYLENEDIOXYBENZENE Property
- Boiling point:
- 94 °C
- Density
- 1,91 g/cm3
- Flash point:
- 111℃
- storage temp.
- 2-8°C(protect from light)
- solubility
- Chloroform, Methanol
- form
- Oil
- color
- Brown
- CAS DataBase Reference
- 5876-51-7(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38-52-41-37/38
- Safety Statements
- 26-36/37/39-39
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29329990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
H412Harmful to aquatic life with long lasting effects
- Precautionary statements
-
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
N-Bromosuccinimide Price
- Product number
- I1251
- Product name
- 5-Iodobenzo[d][1,3]dioxole
- Purity
- min. 98.0 %
- Packaging
- 1G
- Price
- $54
- Updated
- 2025/07/31
- Product number
- I1251
- Product name
- 5-Iodobenzo[d][1,3]dioxole
- Purity
- min. 98.0 %
- Packaging
- 5G
- Price
- $162
- Updated
- 2025/07/31
- Product number
- I708400
- Product name
- 1-Iodo-3,4-methylenedioxybenzene
- Packaging
- 2.5g
- Price
- $100
- Updated
- 2021/12/16
- Product number
- 2H10-H-01
- Product name
- 1-Iodo-3,4-methylenedioxybenzene
- Purity
- 99%
- Packaging
- 1g
- Price
- $63
- Updated
- 2021/12/16
- Product number
- Y6308
- Product name
- 1-Iodo-3,4-methylenedioxybenzene
- Packaging
- 1g
- Price
- $63
- Updated
- 2021/12/16
1-IODO-3,4-METHYLENEDIOXYBENZENE Chemical Properties,Usage,Production
Chemical Properties
Brown Oil
Uses
1-Iodo-3,4-methylenedioxybenzene is an iodinated benzodioxole used in the preparation of various biologically active compounds such as the antiviral and antitumor agents.
Synthesis
274-09-9
5876-51-7
N-iodosuccinimide (14.8 g, 66.0 mmol), 1,3-benzodioxole (6.31 mL, 55.0 mmol) and acetic acid (470 mL) were added to a 1 L flask under argon protection. The reaction mixture was stirred at room temperature for 65 hours. Upon completion of the reaction, the acetic acid was removed by distillation under reduced pressure and the residue was neutralized with saturated aqueous sodium bicarbonate solution. Subsequently, aqueous sodium thiosulfate and chloroform were added to the reaction mixture to separate the organic layer. The aqueous layer was further extracted with chloroform. All organic layers were combined, dried with anhydrous sodium sulfate and concentrated under reduced pressure to give the crude product. The crude product was purified by silica gel column chromatography using hexane as eluent to afford 5-iodo-1,3-benzodioxole (11.3 g, 45.7 mmol, 83% yield) in colorless liquid form.
References
[1] Advanced Synthesis and Catalysis, 2004, vol. 346, # 1, p. 77 - 82
[2] Patent: JP2015/163597, 2015, A. Location in patent: Paragraph 0167; 0168
[3] Synthesis, 1995, # 10, p. 1273 - 1277
[4] Catalysis Science and Technology, 2014, vol. 4, # 12, p. 4308 - 4312
[5] Tetrahedron Letters, 1987, vol. 28, # 41, p. 4879 - 4882
1-IODO-3,4-METHYLENEDIOXYBENZENE Preparation Products And Raw materials
Raw materials
Preparation Products
1-IODO-3,4-METHYLENEDIOXYBENZENE Suppliers
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 86-027-67849912
- Fax
- 86-027-87531808
- sales@chemwish.com
- Country
- China
- ProdList
- 35896
- Advantage
- 56
- Tel
- 010-010-82967028 13522913783
- Fax
- +86-10-82967029
- 2355560935@qq.com
- Country
- China
- ProdList
- 12000
- Advantage
- 60
- Tel
- 13817811078
- Fax
- 86-021-50426522,50426273
- sales@jingyan-chemical.com
- Country
- China
- ProdList
- 9976
- Advantage
- 60
- Tel
- +86-21-54098501
- Fax
- +86-21-54096319
- sales@sinch.com.cn
- Country
- China
- ProdList
- 11598
- Advantage
- 64
- Tel
- 021-50135380
- shchemsky@sina.com
- Country
- China
- ProdList
- 32321
- Advantage
- 50
- Tel
- 021-61551611 13296011611
- Fax
- ＋86 21-50676805
- contact@trustwe.com
- Country
- China
- ProdList
- 9895
- Advantage
- 58
- Tel
- +91-22-26355700
- Fax
- +91-22-26355701
- info@clearsynth.com
- Country
- India
- ProdList
- 9679
- Advantage
- 58
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
View Lastest Price from 1-IODO-3,4-METHYLENEDIOXYBENZENE manufacturers
- Product
- 1-IODO-3,4-METHYLENEDIOXYBENZENE 5876-51-7
- Price
- US $80.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-27
- Product
- 1-IODO-3,4-METHYLENEDIOXYBENZENE 5876-51-7
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2020-03-13