ChemicalBook > CAS DataBase List > 1,2-NAPHTHOQUINONE

1,2-NAPHTHOQUINONE

Product Name
1,2-NAPHTHOQUINONE
CAS No.
524-42-5
Chemical Name
1,2-NAPHTHOQUINONE
Synonyms
1,2-Naphthaquinone;NSC 9831;SID 8139964;1,2-Naftochinon;o-Naphthoquinone;1,2-NAPHTHOQUINONE;BETA-NAPHTHOQUINONE;1,2-NAPHTHALENEDIONE;NAPHTHOQUINONE, 1,2-;ORTHO-NAPHTHOQUINONE
CBNumber
CB8244488
Molecular Formula
C10H6O2
Formula Weight
158.15
MOL File
524-42-5.mol
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1,2-NAPHTHOQUINONE Property

Melting point:
139-142 °C (dec.) (lit.)
Boiling point:
243.22°C (rough estimate)
Density 
1.450 g/cm3 (25℃)
refractive index 
1.5300 (estimate)
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), DMSO (Slightly)
form 
Crystalline Mass or Waxy Solid
color 
Colorless or white to pale yellow
Merck 
14,6394
BRN 
606546
Stability:
Light Sensitive
CAS DataBase Reference
524-42-5(CAS DataBase Reference)
EPA Substance Registry System
1,2-Naphthoquinone (524-42-5)
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Safety

Hazard Codes 
Xn,Xi,C,F
Risk Statements 
22-36/37/38-34-11-25
Safety Statements 
26-36-45-36/37/39-16-37/39-28A
RIDADR 
2811
WGK Germany 
3
RTECS 
QL7000000
Hazard Note 
Irritant
HS Code 
29146990
Hazardous Substances Data
524-42-5(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
N0041
Product name
1,2-Naphthoquinone
Purity
>95.0%(HPLC)(W)
Packaging
1g
Price
$45
Updated
2024/03/01
TCI Chemical
Product number
N0041
Product name
1,2-Naphthoquinone
Purity
>95.0%(HPLC)(W)
Packaging
5g
Price
$120
Updated
2024/03/01
TRC
Product number
N368485
Product name
1,2-Naphthoquinone(90%)
Packaging
10g
Price
$410
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
97658
Product name
1,2-Naphthquinone
Packaging
5G
Price
$590
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0017187
Product name
1,2-NAPHTHOQUINONE
Purity
95.00%
Packaging
1G
Price
$644.46
Updated
2021/12/16
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1,2-NAPHTHOQUINONE Chemical Properties,Usage,Production

Chemical Properties

brown powder

Uses

Chemical reagent and intermediate.

Uses

1,2-Naphthquinone is a highly reactive quinone species which aids in modulating cellular homeostasis and electrophilic signal transduction pathways.

Uses

1,2-Naphthoquinone was employed as mediator during electrochemical mapping of redox activity in normal human breast (MCF-10A) cells by scanning electrochemical microscopy (SECM).

Definition

ChEBI: 1,2-naphthoquinone is the parent structure of the family of 1,2-naphthoquinones, in which the oxo groups of the quinone moiety are at positions 1 and 2 of the naphthalene ring. It is a metabolite of naphthalene and is found in diesel exhaust particles. It has a role as a carcinogenic agent and an aryl hydrocarbon receptor agonist. It derives from a hydride of a naphthalene.

Synthesis Reference(s)

Tetrahedron Letters, 25, p. 603, 1984 DOI: 10.1016/S0040-4039(00)99949-0
The Journal of Organic Chemistry, 51, p. 5390, 1986 DOI: 10.1021/jo00376a061

General Description

Golden yellow needles or brown powder. Decomposes to a bluish-black color on standing.

Air & Water Reactions

The neat chemical may be sensitive to prolonged exposure to air and light. Insoluble in water.

Reactivity Profile

Ketones, such as 1,2-NAPHTHOQUINONE, are reactive with many acids and bases liberating heat and flammable gases (e.g., H2). The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. They react violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4.

Hazard

Irritant

Health Hazard

ACUTE/CHRONIC HAZARDS: 1,2-NAPHTHOQUINONE is an irritant. When heated to decomposition it emits acrid smoke and fumes.

Fire Hazard

Flash point data for 1,2-NAPHTHOQUINONE are not available. 1,2-NAPHTHOQUINONE is probably combustible.

Purification Methods

Crystallise the quinone from ether (red needles) or *benzene (orange leaflets). [Beilstein 7 IV 2417.]

1,2-NAPHTHOQUINONE Preparation Products And Raw materials

Raw materials

Preparation Products

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1,2-NAPHTHOQUINONE Suppliers

GLR Innovations
Tel
+91 9891111994
Email
info@glrgroup.in
Country
India
ProdList
4542
Advantage
58
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View Lastest Price from 1,2-NAPHTHOQUINONE manufacturers

Ouhuang Engineering Materials (Hubei) Co., Ltd
Product
1,2-NAPHTHOQUINONE 524-42-5
Price
US $50.00/kg
Min. Order
1kg
Purity
99.10%
Supply Ability
50000kg
Release date
2024-04-24
Hebei Guanlang Biotechnology Co., Ltd.
Product
1,2-NAPHTHOQUINONE 524-42-5
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2022-09-23
Hebei Mojin Biotechnology Co., Ltd
Product
1,2-NAPHTHOQUINONE 524-42-5
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000tons
Release date
2023-07-31

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