(R)-2-CHLORO-8-CYCLOPENTYL-7-ETHYL-5-METHYL-7,8-DIHYDROPTERIDIN-6(5H)-ONE

Product Name: (R)-2-CHLORO-8-CYCLOPENTYL-7-ETHYL-5-METHYL-7,8-DIHYDROPTERIDIN-6(5H)-ONE
CAS No.: 755039-55-5
Chemical Name: (R)-2-CHLORO-8-CYCLOPENTYL-7-ETHYL-5-METHYL-7,8-DIHYDROPTERIDIN-6(5H)-ONE
Synonyms: 6(5H)-pte;(7R)-2-Ch;BI-2536 parent nucleus;(7R)-2-chloro-8-cyclopentyl-7-ethyl-5-methyl-7H-pteridin-6-one;6(5H)-Pteridinone, 2-chloro-8-cyclopentyl-7-ethyl-7,8-dihydr...;2-Chloro-8-cyclopentyl-7-ethyl-5-Methyl-7,8-dihydro-5H-pteridin-6-one;(R)-2-CHLORO-8-CYCLOPENTYL-7-ETHYL-5-METHYL-7,8-DIHYDROPTERIDIN-6(5H)-ON;(R)-2-CHLORO-8-CYCLOPENTYL-7-ETHYL-5-METHYL-7,8-DIHYDROPTERIDIN-6(5H)-ONE;(R)-2-Chloro-8-cyclopentyl-7-ethyl-5-methyl-7,8-dihydro-5H-pteridin-6-one;(7R)-2-chloro-8-cyclopentyl-7-ethyl-7,8-dihydro-5-Methyl-6(5H)-pteridinone
CBNumber: CB82454722
Molecular Formula: C14H19ClN4O
Formula Weight: 294.78
MOL File: 755039-55-5.mol

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(R)-2-CHLORO-8-CYCLOPENTYL-7-ETHYL-5-METHYL-7,8-DIHYDROPTERIDIN-6(5H)-ONE Property

Boiling point:: 537.5±45.0 °C(Predicted)
Density: 1.263±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 1.45±0.40(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

AK Scientific

Product number: 1735AC
Product name: (R)-2-Chloro-8-cyclopentyl-7-ethyl-5-methyl-7,8-dihydropteridin-6(5H)-one
Packaging: 100mg
Price: $275
Updated: 2021/12/16

AK Scientific

Product number: 1735AC
Product name: (R)-2-Chloro-8-cyclopentyl-7-ethyl-5-methyl-7,8-dihydropteridin-6(5H)-one
Packaging: 250mg
Price: $410
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CCH0032846
Product name: (R)-2-CHLORO-8-CYCLOPENTYL-7-ETHYL-5-METHYL-7,8-DIHYDROPTERIDIN-6(5H)-ONE
Purity: 95.00%
Packaging: 5MG
Price: $495.13
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CCH0032846
Product name: (R)-2-CHLORO-8-CYCLOPENTYL-7-ETHYL-5-METHYL-7,8-DIHYDROPTERIDIN-6(5H)-ONE
Purity: 95.00%
Packaging: 1G
Price: $1253.7
Updated: 2021/12/16

Matrix Scientific

Product number: 122256
Product name: (7R)-2-Chloro-8-cyclopentyl-7-ethyl-7,8-dihydro-5-methyl-6(5H)-pteridinone
Purity: 97.0%
Packaging: 1g
Price: $2344
Updated: 2021/12/16

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(R)-2-CHLORO-8-CYCLOPENTYL-7-ETHYL-5-METHYL-7,8-DIHYDROPTERIDIN-6(5H)-ONE Chemical Properties,Usage,Production

Synthesis

512-56-1

755039-54-4

755039-55-5

(7r)-2-Chloro-8-cyclopentyl-7-ethyl-7,8-dihydro-6(5H)-pteridinone (260 mg, 0.93 mmol) was dissolved in dioxane (5 ml). Trimethyl phosphate (650 mg, 4.6 mmol) and potassium carbonate (192 mg, 1.39 mmol) were added and the reaction mixture was stirred at 90 °C for 6 hours until the ingredients were completely consumed. After completion of the reaction, the mixture was diluted with water and extracted with ethyl acetate. The organic phase was dried over anhydrous sodium sulfate and concentrated under reduced pressure, and the residue was purified by silica gel column chromatography (petroleum ether: ethyl acetate = 1:1) to afford (7R)-2-chloro-8-cyclopentyl-7-ethyl-7,8-dihydro-5-methyl-6(5H)-pteridinone as a white solid (270 mg, 86% yield).1H NMR (CDCl3) δ: 7.7 (s 1H), 4.34 (m, 1H), 4.25 (m, 1H), 3.33 (s, 3H), 2.1-1.6 (m, 10H), 0.86 (t, 3H).

References

[1] Patent: WO2011/79114, 2011, A1. Location in patent: Page/Page column 54; 55

(R)-2-CHLORO-8-CYCLOPENTYL-7-ETHYL-5-METHYL-7,8-DIHYDROPTERIDIN-6(5H)-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-2-CHLORO-8-CYCLOPENTYL-7-ETHYL-5-METHYL-7,8-DIHYDROPTERIDIN-6(5H)-ONE Suppliers

China 65 India 2 United States 5 Global 72

Beijing Ouhe Technology Co., Ltd

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Shanghai Longsheng chemical Co.,Ltd.

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SuZhou ShiYa Biopharmaceuticals, Inc.

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Candia Thamtech Company Limited

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Hubei XinyuanShun Chemical Co., Ltd.

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View Lastest Price from (R)-2-CHLORO-8-CYCLOPENTYL-7-ETHYL-5-METHYL-7,8-DIHYDROPTERIDIN-6(5H)-ONE manufacturers

Career Henan Chemical Co

Product: (7R)-2-chloro-8-cyclopentyl-7-ethyl-5-methyl-7H-pteridin-6-one 755039-55-5
Price: US $3.00/KG
Min. Order: 1KG
Purity: 99
Supply Ability: 100kg
Release date: 2019-07-10

755039-55-5, (R)-2-CHLORO-8-CYCLOPENTYL-7-ETHYL-5-METHYL-7,8-DIHYDROPTERIDIN-6(5H)-ONERelated Search:

(R)-2-CHLORO-8-CYCLOPENTYL-7-ETHYL-5-METHYL-7,8-DIHYDROPTERIDIN-6(5H)-ONE 2-CHLORO-N4,N4-DIMETHYLPYRIMIDINE-4,5-DIAMINE 2-CHLORO-N,N-DIMETHYLPYRIMIDIN-5-AMINE 6(5H)-Pteridinone, 2-chloro-8-cyclopentyl-7-ethyl-7,8-dihydro 2-Chloro-8-methyl-7,8-dihydro-5H-pteridin-6-one 2-Chloro-pteridin

(R)-2-CHLORO-8-CYCLOPENTYL-7-ETHYL-5-METHYL-7,8-DIHYDROPTERIDIN-6(5H)-ONE

6(5H)-Pteridinone, 2-chloro-8-cyclopentyl-7-ethyl-7,8-dihydro-5-Methyl-, (7R)-

2-Chloro-8-cyclopentyl-7-ethyl-5-Methyl-7,8-dihydro-5H-pteridin-6-one

(7R)-2-Ch

6(5H)-pte

6(5H)-Pteridinone, 2-chloro-8-cyclopentyl-7-ethyl-7,8-dihydro-5-Methyl-, (7R)- (7R)-2-Ch

(7R)-2-chloro-8-cyclopentyl-7-ethyl-5-methyl-5,6,7,8-tetrahydropteridin-6-one

(R)-2-Chloro-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropyrimido[4,5-b]pyrazine

(7R)-2-chloro-8-cyclopentyl-7-ethyl-7,8-dihydro-5-Methyl-6(5H)-pteridinone

(R)-2-Chloro-8-cyclopentyl-7-ethyl-5-methyl-7,8-dihydro-5H-pteridin-6-one

(7R)-2-chloro-8-cyclopentyl-7-ethyl-5-methyl-7H-pteridin-6-one

6(5H)-Pteridinone, 2-chloro-8-cyclopentyl-7-ethyl-7,8-dihydr...

BI-2536 parent nucleus

(R)-2-CHLORO-8-CYCLOPENTYL-7-ETHYL-5-METHYL-7,8-DIHYDROPTERIDIN-6(5H)-ON

755039-55-5

755035-55-5

C14H19ClN4O